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Automated interpretation of chest X-rays (CXR) is a critical task with the potential to significantly improve clinical workflow and patient care. While recent advances in multimodal foundation models have shown promise, effectively…

Computer Vision and Pattern Recognition · Computer Science 2025-05-06 Alexander Davis , Rafael Souza , Jia-Hao Lim

Chest X-ray (CXR) imaging is one of the most widely used diagnostic modalities in clinical practice, encompassing a broad spectrum of diagnostic tasks. Recent advancements have seen the extensive application of reasoning-based multimodal…

Artificial intelligence (AI)-based chest X-ray (CXR) interpretation assistants have demonstrated significant progress and are increasingly being applied in clinical settings. However, contemporary medical AI models often adhere to a…

Computer Vision and Pattern Recognition · Computer Science 2025-05-30 Jinquan Guan , Qi Chen , Lizhou Liang , Yuhang Liu , Vu Minh Hieu Phan , Minh-Son To , Jian Chen , Yutong Xie

Recent advances in reasoning-enhanced large language models (LLMs) and multimodal LLMs (MLLMs) have significantly improved performance in complex tasks, yet medical AI models often overlook the structured reasoning processes inherent in…

Artificial Intelligence · Computer Science 2025-05-22 Ziqing Fan , Cheng Liang , Chaoyi Wu , Ya Zhang , Yanfeng Wang , Weidi Xie

Following the impressive development of LLMs, vision-language alignment in LLMs is actively being researched to enable multimodal reasoning and visual IO. This direction of research is particularly relevant to medical imaging because…

Computer Vision and Pattern Recognition · Computer Science 2024-03-19 Suhyeon Lee , Won Jun Kim , Jinho Chang , Jong Chul Ye

Multimodal medical large language models have shown substantial progress in chest X-ray interpretation but continue to face challenges in spatial reasoning and anatomical understanding. Although existing grounding techniques improve overall…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Anees Ur Rehman Hashmi , Numan Saeed , Christoph Lippert

The rapid evolution of artificial intelligence, especially in large language models (LLMs), has significantly impacted various domains, including healthcare. In chest X-ray (CXR) analysis, previous studies have employed LLMs, but with…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Jonggwon Park , Soobum Kim , Byungmu Yoon , Jihun Hyun , Kyoyun Choi

Vision-language models (VLMs) have shown strong promise for medical image analysis, but most remain opaque, offering predictions without the transparent, stepwise reasoning clinicians rely on. We present a framework that brings…

Computer Vision and Pattern Recognition · Computer Science 2025-10-31 Andriy Myronenko , Dong Yang , Baris Turkbey , Mariam Aboian , Sena Azamat , Esra Akcicek , Hongxu Yin , Pavlo Molchanov , Marc Edgar , Yufan He , Pengfei Guo , Yucheng Tang , Daguang Xu

The rapid advancements in large language models (LLMs) have unlocked their potential for multimodal tasks, where text and visual data are processed jointly. However, applying LLMs to medical imaging, particularly for chest X-rays (CXR),…

Image and Video Processing · Electrical Eng. & Systems 2025-02-11 Nicholas Evans , Stephen Baker , Miles Reed

Medical report generation automates radiology descriptions from images, easing the burden on physicians and minimizing errors. However, current methods lack structured outputs and physician interactivity for clear, clinically relevant…

Artificial Intelligence · Computer Science 2024-04-18 Hongzhao Li , Hongyu Wang , Xia Sun , Hua He , Jun Feng

Longitudinal chest X-ray (CXR) interpretation requires reasoning over disease evolution across multiple patient visits, yet most existing medical VQA benchmarks focus on single images or short-horizon image pairs. We introduce MI-CXR, a…

Computer Vision and Pattern Recognition · Computer Science 2026-05-18 Sunghwan Steve Cho , Yunseok Han , Jaeyoung Do

Chest X-rays (CXRs) are among the most frequently performed imaging examinations worldwide, yet rising imaging volumes increase radiologist workload and the risk of diagnostic errors. Although artificial intelligence (AI) systems have shown…

Multimodal Large Language Models (MLLMs) have shown success in various general image processing tasks, yet their application in medical imaging is nascent, lacking tailored models. This study investigates the potential of MLLMs in improving…

Computer Vision and Pattern Recognition · Computer Science 2024-05-13 Ling Yang , Zhanyu Wang , Zhenghao Chen , Xinyu Liang , Luping Zhou

Chest X-ray imaging is crucial for diagnosing pulmonary and cardiac diseases, yet its interpretation demands extensive clinical experience and suffers from inter-observer variability. While deep learning models offer high diagnostic…

Computer Vision and Pattern Recognition · Computer Science 2025-08-19 Chee Ng , Liliang Sun , Shaoqing Tang

Multimodal artificial intelligence (AI) systems have the potential to enhance clinical decision-making by interpreting various types of medical data. However, the effectiveness of these models across all medical fields is uncertain. Each…

Precise spatial modeling in the operating room (OR) is foundational to many clinical tasks, supporting intraoperative awareness, hazard avoidance, and surgical decision-making. While existing approaches leverage large-scale multimodal…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Peiqi He , Zhenhao Zhang , Yixiang Zhang , Xiongjun Zhao , Shaoliang Peng

Large Vision Language Models (LVLMs) show promise in medical applications, but their inability to faithfully ground responses in visual evidence raises serious concerns about clinical trustworthiness. While visual attribution methods are…

Computer Vision and Pattern Recognition · Computer Science 2026-05-20 Guangzhi Xiong , Qiao Jin , Sanchit Sinha , Zhiyong Lu , Aidong Zhang

Significant methodological strides have been made toward Chest X-ray (CXR) understanding via modern vision-language models (VLMs), demonstrating impressive Visual Question Answering (VQA) and CXR report generation abilities. However,…

Artificial Intelligence · Computer Science 2024-04-01 Seil Kang , Donghyun Kim , Junhyeok Kim , Hyo Kyung Lee , Seong Jae Hwang

Cross-modal reasoning (CMR), the intricate process of synthesizing and drawing inferences across divergent sensory modalities, is increasingly recognized as a crucial capability in the progression toward more sophisticated and…

Computation and Language · Computer Science 2024-10-01 Shengsheng Qian , Zuyi Zhou , Dizhan Xue , Bing Wang , Changsheng Xu

Chest X-ray (CXR) plays a pivotal role in clinical diagnosis, and a variety of task-specific and foundation models have been developed for automatic CXR interpretation. However, these models often struggle to adapt to new diagnostic tasks…

Artificial Intelligence · Computer Science 2025-10-27 Jinhui Lou , Yan Yang , Zhou Yu , Zhenqi Fu , Weidong Han , Qingming Huang , Jun Yu
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