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Human language is one of the most expressive tools for conveying intent, yet most artificial or biological systems lack mechanisms to interpret or respond meaningfully to it. Bridging this gap could enable more natural forms of control over…

Artificial Intelligence · Computer Science 2025-09-16 Nam H. Le , Patrick Erickson , Yanbo Zhang , Michael Levin , Josh Bongard

Large language models (LLMs) are transforming cellular biology by enabling the development of "virtual cells"--computational systems that represent, predict, and reason about cellular states and behaviors. This work provides a comprehensive…

Computation and Language · Computer Science 2025-10-10 Krinos Li , Xianglu Xiao , Shenglong Deng , Lucas He , Zijun Zhong , Yuanjie Zou , Zhonghao Zhan , Zheng Hui , Weiye Bao , Guang Yang

Simulation is an invaluable tool for developing and evaluating controllers for self-driving cars. Current simulation frameworks are driven by highly-specialist domain specific languages, and so a natural language interface would greatly…

Artificial Intelligence · Computer Science 2023-10-27 Antonio Valerio Miceli-Barone , Alex Lascarides , Craig Innes

The evolution of Large Language Models (LLMs) has showcased remarkable capacities for logical reasoning and natural language comprehension. These capabilities can be leveraged in solutions that semantically and textually model complex…

Human-Computer Interaction · Computer Science 2024-04-17 Syed Mekael Wasti , Ken Q. Pu , Ali Neshati

Large language models (LLMs) enable system builders today to create competent NLP systems through prompting, where they only need to describe the task in natural language and provide a few examples. However, in other ways, LLMs are a step…

Computation and Language · Computer Science 2023-08-24 Vijay Viswanathan , Chenyang Zhao , Amanda Bertsch , Tongshuang Wu , Graham Neubig

In this paper, we present a groundbreaking paradigm for human-computer interaction that revolutionizes the traditional notion of an operating system. Within this innovative framework, user requests issued to the machine are handled by an…

Machine Learning · Computer Science 2023-10-10 Gabriele Tolomei , Cesare Campagnano , Fabrizio Silvestri , Giovanni Trappolini

Prompting has become a practical method for utilizing pre-trained language models (LMs). This approach offers several advantages. It allows an LM to adapt to new tasks with minimal training and parameter updates, thus achieving efficiency…

Audio and Speech Processing · Electrical Eng. & Systems 2024-08-26 Kai-Wei Chang , Haibin Wu , Yu-Kai Wang , Yuan-Kuei Wu , Hua Shen , Wei-Cheng Tseng , Iu-thing Kang , Shang-Wen Li , Hung-yi Lee

Traditional psychological experiments utilizing naturalistic stimuli face challenges in manual annotation and ecological validity. To address this, we introduce a novel paradigm leveraging multimodal large language models (LLMs) as proxies…

Artificial Intelligence · Computer Science 2025-02-27 Xin Liu , Ziyue Zhang , Jingxin Nie

Since the advent of GPT, large language models (LLMs) have brought about revolutionary advancements in all walks of life. As a superior natural language processing (NLP) technology, LLMs have consistently achieved state-of-the-art…

Networking and Internet Architecture · Computer Science 2024-06-26 Danshi Wang , Yidi Wang , Xiaotian Jiang , Yao Zhang , Yue Pang , Min Zhang

Simulated Students offer a valuable methodological framework for evaluating pedagogical approaches and modelling diverse learner profiles, tasks which are otherwise challenging to undertake systematically in real-world settings. Recent…

Computers and Society · Computer Science 2025-11-11 Luis Marquez-Carpintero , Alberto Lopez-Sellers , Miguel Cazorla

Large Language Models (LLMs) have gained widespread popularity due to their ability to perform ad-hoc Natural Language Processing (NLP) tasks with a simple natural language prompt. Part of the appeal for LLMs is their approachability to the…

Human-Computer Interaction · Computer Science 2025-02-25 Aditi Mishra , Utkarsh Soni , Anjana Arunkumar , Jinbin Huang , Bum Chul Kwon , Chris Bryan

While Large Language Models (LLMs) are being quickly adapted to many domains, including healthcare, their strengths and pitfalls remain under-explored. In our study, we examine the effects of prompt engineering to guide Large Language…

Computation and Language · Computer Science 2024-09-04 Daniil Filienko , Yinzhou Wang , Caroline El Jazmi , Serena Xie , Trevor Cohen , Martine De Cock , Weichao Yuwen

Recent developments in large language models (LLMs) have unlocked new opportunities for healthcare, from information synthesis to clinical decision support. These new LLMs are not just capable of modeling language, but can also act as…

Human-Computer Interaction · Computer Science 2023-09-21 Nikita Mehandru , Brenda Y. Miao , Eduardo Rodriguez Almaraz , Madhumita Sushil , Atul J. Butte , Ahmed Alaa

Large Language models (LLMs) have emerged as powerful tools for addressing challenges across diverse domains. Notably, recent studies have demonstrated that large language models significantly enhance the efficiency of biomolecular analysis…

Computation and Language · Computer Science 2025-03-07 Jiyue Jiang , Zikang Wang , Yuheng Shan , Heyan Chai , Jiayi Li , Zixian Ma , Xinrui Zhang , Yu Li

Large language models (LLMs), inspired by neuroscience, exhibit behaviors that often evoke a sense of personality and intelligence-yet the mechanisms behind these effects remain elusive. Here, we operationalize Conceptual Blending Theory…

Computation and Language · Computer Science 2025-05-19 Makoto Sato

Recent advances in Generative Artificial Intelligence, particularly Large Language Models (LLMs), have stimulated growing interest in automating or assisting Business Process Modeling tasks using natural language. Several approaches have…

Software Engineering · Computer Science 2026-04-16 João Bettencourt , Sérgio Guerreiro

Prompt engineering has emerged as an indispensable technique for extending the capabilities of large language models (LLMs) and vision-language models (VLMs). This approach leverages task-specific instructions, known as prompts, to enhance…

Artificial Intelligence · Computer Science 2025-03-18 Pranab Sahoo , Ayush Kumar Singh , Sriparna Saha , Vinija Jain , Samrat Mondal , Aman Chadha

Large Language Models (LLMs) are trained and aligned to follow natural language instructions with only a handful of examples, and they are prompted as task-driven autonomous agents to adapt to various sources of execution environments.…

Computation and Language · Computer Science 2023-10-03 Yang Su

Prompt engineering has emerged as a powerful technique for guiding large language models (LLMs) toward desired responses, significantly enhancing their performance across diverse tasks. Beyond their role as static predictors, LLMs…

Machine Learning · Computer Science 2025-03-27 Ryumei Nakada , Wenlong Ji , Tianxi Cai , James Zou , Linjun Zhang

Large language models (LLMs) are increasingly seen as assistants, copilots, and consultants, capable of supporting a wide range of tasks through natural conversation. However, most systems remain constrained by a linear request-response…

Computation and Language · Computer Science 2026-05-05 Jiaqi Chen , Yanzhe Zhang , Yutong Zhang , Yijia Shao , Diyi Yang
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