English
Related papers

Related papers: Correcting Multiple Substitutions in Nanopore-Sequ…

200 papers

Motivation: New long read sequencers promise to transform sequencing and genome assembly by producing reads tens of kilobases long. However their high error rate significantly complicates assembly and requires expensive correction steps to…

Genomics · Quantitative Biology 2017-07-18 Antoine Recanati , Thomas Brüls , Alexandre d'Aspremont

In this work, we investigate the problem of constructing codes capable of correcting two deletions. In particular, we construct a code that requires redundancy approximately 8 log n + O(log log n) bits of redundancy, where n is the length…

Information Theory · Computer Science 2018-05-02 Ryan Gabrys , Frederic Sala

Recent work by Smagloy et al. (ISIT 2020) shows that the redundancy of a single-deletion $s$-substitution correcting code is asymptotically at least $(s+1)\log n+o(\log n)$, where $n$ is the length of the codes. They also provide a…

Information Theory · Computer Science 2020-11-24 Wentu Song , Nikita Polyanskii , Kui Cai , Xuan He

Due to its high data density and longevity, DNA is considered a promising medium for satisfying ever-increasing data storage needs. However, the diversity of errors that occur in DNA sequences makes efficient error-correction a challenging…

Information Theory · Computer Science 2020-11-12 Yuanyuan Tang , Farzad Farnoud

We first give a construction of binary $t_1$-deletion-$t_2$-insertion-burst correcting codes with redundancy at most $\log(n)+(t_1-t_2-1)\log\log(n)+O(1)$, where $t_1\ge 2t_2$. Then we give an improved construction of binary codes capable…

Information Theory · Computer Science 2022-11-23 Zuo Ye , Ohad Elishco

Nanopore sequencing can read substantially longer sequences of nucleic acid molecules, called reads, than other sequencing methods, which has led to advances in genomic analysis such as the gapless human genome assembly. By analyzing the…

Genomics · Quantitative Biology 2026-05-21 Simon Ambrozak , Ulysse McConnell , Bhargav Srinivasan , Burak Ozkan , Ernest Zhang , Can Firtina

We study deletion-correcting codes for an adversarial nanopore channel in which at most $t$ deletions may occur. We propose an explicit construction of $q$-ary codes of length $n$ for this channel with $2t\log_q n+\Theta(\log\log n)$…

Information Theory · Computer Science 2026-03-03 Huiling Xie , Zitan Chen

Reconstruction codes are generalizations of error-correcting codes that can correct errors by a given number of noisy reads. The study of such codes was initiated by Levenshtein in 2001 and developed recently due to applications in modern…

Information Theory · Computer Science 2023-02-21 Zuo Ye , Xin Liu , Xiande Zhang , Gennian Ge

Quantum error correction is expected to be essential in large-scale quantum technologies. However, the substantial overhead of qubits it requires is thought to greatly limit its utility in smaller, near-term devices. Here we introduce a new…

Quantum Physics · Physics 2020-01-20 David Layden , Mo Chen , Paola Cappellaro

We study segmented burst-deletion channels motivated by the observation that synchronization errors commonly occur in a bursty manner in real-world settings. In this channel model, transmitted sequences are implicitly divided into…

Information Theory · Computer Science 2025-07-21 Yajuan Liu , Tolga M. Duman

Near term quantum computers suffer from the presence of different noise sources. In order to mitigate for this effect and acquire results with significantly better accuracy, there is the urge of designing efficient error correction or error…

The analysis of the decoding failure rate of the bit-flipping algorithm has received increasing attention. For a binary linear code we consider the minimum number of rows in a parity-check matrix such that the bit-flipping algorithm is able…

Information Theory · Computer Science 2024-02-05 Jens Zumbrägel

Error correction is essential for modern computing systems, enabling information to be processed accurately even in the presence of noise. Here, we demonstrate a new approach which exploits an error correcting phase that emerges in a system…

Motivated by the concept of probe storage, we study the problem of information retrieval using a large array of N nano-mechanical probes, N ~ 4000. At the nanometer scale it is impossible to avoid errors in the positioning of the array,…

Information Theory · Computer Science 2015-03-18 Oliver Hambrey , Thomas Parnell , Oleg Zaboronski

In this paper, we consider a recent channel model of a nanopore sequencer proposed by McBain, Viterbo, and Saunderson (2024), termed the noisy nanopore channel (NNC). In essence, an NNC is a duplication channel with structured, Markov…

Information Theory · Computer Science 2025-04-25 V. Arvind Rameshwar , Nir Weinberger

The scaling of high density NOR Flash memory devices with multi level cell (MLC) hits the reliability break wall because of relatively high intrinsic bit error rate (IBER). The chip maker companies offer two solutions to meet the output bit…

Information Theory · Computer Science 2013-06-25 Daniel L. Miller

DNA is an attractive candidate for data storage. Its millennial durability and nanometer scale offer exceptional data density and longevity. Its relevance to medical applications also drives advances in DNA-related biotechnology. To protect…

Information Theory · Computer Science 2025-11-25 Yu-Ting Lin , Hsin-Po Wang , Venkatesan Guruswami

The problem of error correction in both coherent and noncoherent network coding is considered under an adversarial model. For coherent network coding, where knowledge of the network topology and network code is assumed at the source and…

Information Theory · Computer Science 2019-05-07 Danilo Silva , Frank R. Kschischang

Nanopore sequencing technology remains highly error-prone, making efficient error correction essential in DNA-based data storage. Prior work addressed high error rates using convolutional codes with their decoder coupled with the…

Information Theory · Computer Science 2026-04-02 Anisha Banerjee , Roman Sokolovskii , Thomas Heinis , Antonia Wachter-Zeh , Eirik Rosnes , Alexandre Graell i Amat

Adequate read filtering is critical when processing high-throughput data in marker-gene-based studies. Sequencing errors can cause the mis-clustering of otherwise similar reads, artificially increasing the number of retrieved Operational…

Quantitative Methods · Quantitative Biology 2015-06-02 Fernando Puente-Sánchez , Jacobo Aguirre , Víctor Parro