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Large language models (LLMs) are rapidly transforming various domains, including biomedicine and healthcare, and demonstrate remarkable potential from scientific research to new drug discovery. Graph-based retrieval-augmented generation…

Quantitative Methods · Quantitative Biology 2025-11-14 Guofeng Meng , Li Shen , Qiuyan Zhong , Wei Wang , Haizhou Zhang , Xiaozhen Wang

Owing to their unprecedented comprehension capabilities, large language models (LLMs) have become indispensable components of modern web search engines. From a technical perspective, this integration represents retrieval-augmented…

Information Retrieval · Computer Science 2026-02-10 Xingyuan Zeng , Zuohan Wu , Yue Wang , Chen Zhang , Quanming Yao , Libin Zheng , Jian Yin

Retrieval-Augmented Generation (RAG) is a promising approach to mitigate hallucinations in Large Language Models (LLMs) for legal applications, but its reliability is critically dependent on the accuracy of the retrieval step. This is…

Computation and Language · Computer Science 2025-10-09 Markus Reuter , Tobias Lingenberg , Rūta Liepiņa , Francesca Lagioia , Marco Lippi , Giovanni Sartor , Andrea Passerini , Burcu Sayin

We present a comprehensive study of answer quality evaluation in Retrieval-Augmented Generation (RAG) applications using vRAG-Eval, a novel grading system that is designed to assess correctness, completeness, and honesty. We further map the…

Computation and Language · Computer Science 2024-11-08 Yang Wang , Alberto Garcia Hernandez , Roman Kyslyi , Nicholas Kersting

We present a new benchmark for evaluating Deep Search--a realistic and complex form of retrieval-augmented generation (RAG) that requires source-aware, multi-hop reasoning over diverse, sparsed, but related sources. These include documents,…

Computation and Language · Computer Science 2025-07-01 Prafulla Kumar Choubey , Xiangyu Peng , Shilpa Bhagavath , Kung-Hsiang Huang , Caiming Xiong , Chien-Sheng Wu

Retrieval-Augmented Generation (RAG) based on Large Language Models (LLMs) is a powerful solution to understand and query the industry's closed-source documents. However, basic RAG often struggles with complex QA tasks in legal and…

Information Retrieval · Computer Science 2025-09-08 Huifeng Lin , Gang Su , Jintao Liang , You Wu , Rui Zhao , Ziyue Li

Despite notable advancements in Retrieval-Augmented Generation (RAG) systems that expand large language model (LLM) capabilities through external retrieval, these systems often struggle to meet the complex and diverse needs of real-world…

Computation and Language · Computer Science 2025-03-13 Jinyu Wang , Jingjing Fu , Rui Wang , Lei Song , Jiang Bian

Recent proprietary large language models (LLMs), such as GPT-4, have achieved a milestone in tackling diverse challenges in the biomedical domain, ranging from multiple-choice questions to long-form generations. To address challenges that…

Computation and Language · Computer Science 2024-06-19 Minbyul Jeong , Jiwoong Sohn , Mujeen Sung , Jaewoo Kang

Retrieval-augmented generation (RAG) can enhance the generation quality of large language models (LLMs) by incorporating external token databases. However, retrievals from large databases can constitute a substantial portion of the overall…

Computation and Language · Computer Science 2024-03-12 Wenqi Jiang , Shuai Zhang , Boran Han , Jie Wang , Bernie Wang , Tim Kraska

Retrieval-Augmented Generation (RAG) encounters efficiency challenges when scaling to massive knowledge bases while preserving contextual relevance. We propose Hash-RAG, a framework that integrates deep hashing techniques with systematic…

Information Retrieval · Computer Science 2025-06-04 Jinyu Guo , Xunlei Chen , Qiyang Xia , Zhaokun Wang , Jie Ou , Libo Qin , Shunyu Yao , Wenhong Tian

Large language models (LLMs) struggle with relation completion (RC), both with and without retrieval-augmented generation (RAG), particularly when the required information is rare or sparsely represented. To address this, we propose a novel…

Computation and Language · Computer Science 2026-04-27 Fahmida Alam , Mihai Surdeanu , Ellen Riloff

In enterprise datasets, documents are rarely pure. They are not just text, nor just numbers; they are a complex amalgam of narrative and structure. Current Retrieval-Augmented Generation (RAG) systems have attempted to address this…

Artificial Intelligence · Computer Science 2026-01-16 Alex Dantart , Marco Kóvacs-Navarro

Although Large Language Models (LLMs) demonstrate significant capabilities, their reliance on parametric knowledge often leads to inaccuracies. Retrieval Augmented Generation (RAG) mitigates this by incorporating external knowledge, but…

Artificial Intelligence · Computer Science 2025-11-04 Hailong Yin , Bin Zhu , Jingjing Chen , Chong-Wah Ngo

We propose a scalable and cost-efficient framework for deploying Graph-based Retrieval-Augmented Generation (GraphRAG) in enterprise environments. While GraphRAG has shown promise for multi- hop reasoning and structured retrieval, its…

Artificial Intelligence · Computer Science 2025-12-19 Congmin Min , Sahil Bansal , Joyce Pan , Abbas Keshavarzi , Rhea Mathew , Amar Viswanathan Kannan

Retrieval-augmented generation (RAG) is a powerful technique that enhances downstream task execution by retrieving additional information, such as knowledge, skills, and tools from external sources. Graph, by its intrinsic "nodes connected…

Recent research in retrieval-augmented generation (RAG) has concentrated on retrieving useful information from candidate documents. However, numerous methodologies frequently neglect the calibration capabilities of large language models…

Computation and Language · Computer Science 2025-06-23 Guanhua Chen , Yutong Yao , Lidia S. Chao , Xuebo Liu , Derek F. Wong

Retrieval-Augmented Generation (RAG) mitigates LLM hallucinations but introduces a critical vulnerability: corpus integrity. We present SilentRetrieval, a two-stage data poisoning attack that hijacks RAG systems through adversarially…

Cryptography and Security · Computer Science 2026-05-28 Jiachen Qian

Purpose: Large Language Models (LLMs) hold significant promise for medical applications. Retrieval Augmented Generation (RAG) emerges as a promising approach for customizing domain knowledge in LLMs. This case study presents the development…

Short answer assessment is a vital component of science education, allowing evaluation of students' complex three-dimensional understanding. Large language models (LLMs) that possess human-like ability in linguistic tasks are increasingly…

Computation and Language · Computer Science 2025-06-05 Yucheng Chu , Peng He , Hang Li , Haoyu Han , Kaiqi Yang , Yu Xue , Tingting Li , Joseph Krajcik , Jiliang Tang

Retrieval-Augmented Generation (RAG) has become a core paradigm in document question answering tasks. However, existing methods have limitations when dealing with multimodal documents: one category of methods relies on layout analysis and…

Computation and Language · Computer Science 2026-03-09 Wang Chen , Wenhan Yu , Guanqiang Qi , Weikang Li , Yang Li , Lei Sha , Deguo Xia , Jizhou Huang