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Predictive coding (PC) is a general theory of cortical function. The local, gradient-based learning rules found in one kind of PC model have recently been shown to closely approximate backpropagation. This finding suggests that this…

Neural and Evolutionary Computing · Computer Science 2021-12-09 Nick Alonso , Emre Neftci

Spiking neural networks (SNN) are delivering energy-efficient, massively parallel, and low-latency solutions to AI problems, facilitated by the emerging neuromorphic chips. To harness these computational benefits, SNN need to be trained by…

Neural and Evolutionary Computing · Computer Science 2021-10-28 Guangzhi Tang , Neelesh Kumar , Ioannis Polykretis , Konstantinos P. Michmizos

Plasticity circuits in the brain are known to be influenced by the distribution of the synaptic weights through the mechanisms of synaptic integration and local regulation of synaptic strength. However, the complex interplay of…

Neural and Evolutionary Computing · Computer Science 2021-04-26 Giorgia Dellaferrera , Stanislaw Wozniak , Giacomo Indiveri , Angeliki Pantazi , Evangelos Eleftheriou

Memory is a key component of biological neural systems that enables the retention of information over a huge range of temporal scales, ranging from hundreds of milliseconds up to years. While Hebbian plasticity is believed to play a pivotal…

Neural and Evolutionary Computing · Computer Science 2022-05-24 Thomas Limbacher , Ozan Özdenizci , Robert Legenstein

Artificial neural networks (ANNs) are typically confined to accomplishing pre-defined tasks by learning a set of static parameters. In contrast, biological neural networks (BNNs) can adapt to various new tasks by continually updating the…

Artificial Intelligence · Computer Science 2022-09-20 Fan Wang , Hao Tian , Haoyi Xiong , Hua Wu , Jie Fu , Yang Cao , Yu Kang , Haifeng Wang

We present results from a new approach to learning and plasticity in neuromorphic hardware systems: to enable flexibility in implementable learning mechanisms while keeping high efficiency associated with neuromorphic implementations, we…

Neurons and Cognition · Quantitative Biology 2016-10-14 Simon Friedmann , Johannes Schemmel , Andreas Gruebl , Andreas Hartel , Matthias Hock , Karlheinz Meier

Gradient-based algorithms are a cornerstone of artificial neural network training, yet it remains unclear whether biological neural networks use similar gradient-based strategies during learning. Experiments often discover a diversity of…

Machine Learning · Computer Science 2026-04-29 Hugo Ninou , Jonathan Kadmon , N. Alex Cayco-Gajic

Continual learning is the problem of sequentially learning new tasks or knowledge while protecting previously acquired knowledge. However, catastrophic forgetting poses a grand challenge for neural networks performing such learning process.…

Machine Learning · Computer Science 2020-07-01 Vithursan Thangarasa , Thomas Miconi , Graham W. Taylor

We introduce a novel, biologically plausible local learning rule that provably increases the robustness of neural dynamics to noise in nonlinear recurrent neural networks with homogeneous nonlinearities. Our learning rule achieves higher…

Neurons and Cognition · Quantitative Biology 2022-10-12 Christopher H. Stock , Sarah E. Harvey , Samuel A. Ocko , Surya Ganguli

Biological neural networks self-organize according to local synaptic modifications to produce stable computations. How modifications at the synaptic level give rise to such computations at the network level remains an open question.…

Neurons and Cognition · Quantitative Biology 2026-01-21 David Lipshutz , Robert J. Lipshutz

Synaptic delays play a crucial role in biological neuronal networks, where their modulation has been observed in mammalian learning processes. In the realm of neuromorphic computing, although spiking neural networks (SNNs) aim to emulate…

Neural and Evolutionary Computing · Computer Science 2025-06-19 Marissa Dominijanni , Alexander Ororbia , Kenneth W. Regan

Deep learning has seen remarkable developments over the last years, many of them inspired by neuroscience. However, the main learning mechanism behind these advances - error backpropagation - appears to be at odds with neurobiology. Here,…

Neurons and Cognition · Quantitative Biology 2018-10-29 João Sacramento , Rui Ponte Costa , Yoshua Bengio , Walter Senn

This study proposes voltage-dependent-synaptic plasticity (VDSP), a novel brain-inspired unsupervised local learning rule for the online implementation of Hebb's plasticity mechanism on neuromorphic hardware. The proposed VDSP learning rule…

Hebbian learning is a key principle underlying learning in biological neural networks. We relate a Hebbian spike-timing-dependent plasticity rule to noisy gradient descent with respect to a non-convex loss function on the probability…

Machine Learning · Computer Science 2026-01-14 Niklas Dexheimer , Sascha Gaudlitz , Johannes Schmidt-Hieber

This paper presents a spike-based model which employs neurons with functionally distinct dendritic compartments for classifying high dimensional binary patterns. The synaptic inputs arriving on each dendritic subunit are nonlinearly…

Neural and Evolutionary Computing · Computer Science 2014-11-26 Shaista Hussain , Shih-Chii Liu , Arindam Basu

Most normative models in computational neuroscience describe the task of learning as the optimisation of a cost function with respect to a set of parameters. However, learning as optimisation fails to account for a time varying environment…

Neurons and Cognition · Quantitative Biology 2020-08-10 Jannes Jegminat , Jean-Pascal Pfister

Backpropagation (BP) has been pivotal in advancing machine learning and remains essential in computational applications and comparative studies of biological and artificial neural networks. Despite its widespread use, the implementation of…

Neurons and Cognition · Quantitative Biology 2025-04-15 Xinhao Fan , Shreesh P Mysore

Memristors have been widely studied as artificial synapses in neuromorphic circuits, due to their functional similarity with biological synapses, low operating power, and high integration density. In this work, a memristive synapse,…

Emerging Technologies · Computer Science 2023-08-29 Y. Liu , D. Wang , Z. Dong , H. Xie , W. Zhao

In many normative theories of synaptic plasticity, weight updates implicitly depend on the chosen parametrization of the weights. This problem relates, for example, to neuronal morphology: synapses which are functionally equivalent in terms…

Neurons and Cognition · Quantitative Biology 2022-02-25 Elena Kreutzer , Walter M. Senn , Mihai A. Petrovici

Understanding how biological neural networks carry out learning using spike-based local plasticity mechanisms can lead to the development of powerful, energy-efficient, and adaptive neuromorphic processing systems. A large number of…

Neural and Evolutionary Computing · Computer Science 2022-11-08 Lyes Khacef , Philipp Klein , Matteo Cartiglia , Arianna Rubino , Giacomo Indiveri , Elisabetta Chicca