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Quantum computers are often treated as experimental add-ons that are loosely coupled to classical infrastructure through high-level interpreted languages and cloud-like orchestration. However, future deployments in both, high-performance…

Quantum Physics · Physics 2025-07-28 Ralf Ramsauer , Wolfgang Mauerer

To address the growing needs for scalable High Performance Computing (HPC) and Quantum Computing (QC) integration, we present our HPC-QC full stack framework and its hybrid workload development capability with modular…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-10-24 Xin Zhan , K. Grace Johnson , Aniello Esposito , Barbara Chapman , Marco Fiorentino , Kirk M. Bresniker , Raymond G. Beausoleil , Masoud Mohseni

As quantum computing (QC) technologies mature, their integration into established high-performance computing (HPC) infrastructures is becoming a central objective for next-generation computing systems. However, unlocking the potential of…

Quantum computing has the potential to surpass the capabilities of current classical computers when solving complex problems. Combinatorial optimization has emerged as one of the key target areas for quantum computers as problems found in…

Quantum Physics · Physics 2023-07-27 Juan Giraldo , José Ossorio , Norha M. Villegas , Gabriel Tamura , Ulrike Stege

A quantum processing unit (QPU) must contain a large number of high quality qubits to produce accurate results for problems at useful scales. In contrast, most scientific and industry classical computation workloads happen in parallel on…

Emerging Technologies · Computer Science 2025-02-06 Wei Tang , Margaret Martonosi

Quantum computers promise exponential speed ups over classical computers for various tasks. This emerging technology is expected to have its first huge impact in High Performance Computing (HPC), as it can solve problems beyond the reach of…

Quantum Physics · Physics 2024-03-29 Arnaud Gazda , Oceane Koska

Demonstrating quantum advantage has been a pressing challenge in the field. Most claimed quantum speedups rely on a subroutine in which classical information can be accessed in a coherent quantum manner, which imposes a crucial constraint…

Quantum Physics · Physics 2025-11-04 Nhat A. Nghiem

The technology of Quantum Computing (QC) is continuously evolving, as researchers explore new technologies and the public gains access to quantum computers with an increasing number of qubits. In addition, the research community and…

Quantum computing promises to tackle technological and industrial problems insurmountable for classical computers. However, today's quantum computers still have limited demonstrable functionality, and it is expected that scaling up to…

Scientific applications are starting to explore the viability of quantum computing. This exploration typically begins with quantum simulations that can run on existing classical platforms, albeit without the performance advantages of real…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-08-16 Amir Shehata , Thomas Naughton , In-Saeng Suh

Quantum computing is an emerging computational paradigm that leverages the laws of quantum mechanics to perform elementary logic operations. Existing programming models for quantum computing were designed with fault-tolerant hardware in…

Programming Languages · Computer Science 2019-09-06 Tiffany M. Mintz , Alexander J. Mccaskey , Eugene F. Dumitrescu , Shirley V. Moore , Sarah Powers , Pavel Lougovski

Near term quantum devices have the potential to outperform classical computing through the use of hybrid classical-quantum algorithms such as Variational Quantum Eigensolvers. These iterative algorithms use a classical optimiser to update a…

Quantum Physics · Physics 2024-01-17 A. M. Krol , K. Mesman , A. Sarkar , M. Möller , Z. Al-Ars

Hybrid quantum-classical applications pose significant resource management challenges due to heterogeneity and dynamism in both infrastructure and workloads. Quantum-HPC environments integrate quantum processing units (QPUs) with diverse…

Quantum Physics · Physics 2026-04-07 Pradeep Mantha , Florian J. Kiwit , Nishant Saurabh , Shantenu Jha , Andre Luckow

We describe Qonductor, a cloud orchestrator for hybrid quantum-classical applications that run on heterogeneous hybrid resources. Qonductor abstracts away the complexity of hybrid programming and resource management by exposing the…

Integrating quantum mechanics into drug discovery marks a decisive shift from empirical trial-and-error toward quantitative precision. However, the prohibitive cost of ab initio molecular dynamics has historically forced a compromise…

Quantum computing is a promising paradigm based on quantum theory for performing fast computations. Quantum algorithms are expected to surpass their classical counterparts in terms of computational complexity for certain tasks, including…

High-performance computing systems are rapidly evolving into heterogeneous platforms that fuse quantum accelerators with traditional classical processing units (CPUs) and graphical processing units (GPUs). This convergence calls for…

Fault tolerance is a long-term objective driving many companies and research organizations to compete in making current, imperfect quantum computers useful - Quantum Utility (QU). It looks promising to achieve this by leveraging software…

Quantum Physics · Physics 2024-09-27 Markiian Tsymbalista , Ihor Katernyak

Recent computations involving quantum processing units (QPUs) have demonstrated a series of challenges inherent to hybrid classical-quantum programming, compilation, execution, and verification and validation. Despite considerable progress,…

Quantum Physics · Physics 2018-05-24 Alexander McCaskey , Eugene Dumitrescu , Dmitry Liakh , Travis Humble

Quantum computers have demonstrated utility in simulating quantum systems beyond brute-force classical approaches. As the community builds on these demonstrations to explore using quantum computing for applied research, algorithms and…