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One of the grand challenges of cell biology is inferring the gene regulatory network (GRN) which describes interactions between genes and their products that control gene expression and cellular function. We can treat this as a causal…

Machine Learning · Computer Science 2023-12-27 Lazar Atanackovic , Alexander Tong , Bo Wang , Leo J. Lee , Yoshua Bengio , Jason Hartford

Deep generative frameworks including GANs and normalizing flow models have proven successful at filling in missing values in partially observed data samples by effectively learning -- either explicitly or implicitly -- complex,…

Machine Learning · Computer Science 2021-04-06 Edgar A. Bernal

We introduce BatchGFN -- a novel approach for pool-based active learning that uses generative flow networks to sample sets of data points proportional to a batch reward. With an appropriate reward function to quantify the utility of…

Machine Learning · Computer Science 2023-06-28 Shreshth A. Malik , Salem Lahlou , Andrew Jesson , Moksh Jain , Nikolay Malkin , Tristan Deleu , Yoshua Bengio , Yarin Gal

A robust theoretical framework that can describe and predict the generalization ability of deep neural networks (DNNs) in general circumstances remains elusive. Classical attempts have produced complexity metrics that rely heavily on global…

Machine Learning · Computer Science 2020-01-20 Marelie H. Davel , Marthinus W. Theunissen , Arnold M. Pretorius , Etienne Barnard

Despite the widespread practical success of deep learning methods, our theoretical understanding of the dynamics of learning in deep neural networks remains quite sparse. We attempt to bridge the gap between the theory and practice of deep…

Neural and Evolutionary Computing · Computer Science 2014-02-20 Andrew M. Saxe , James L. McClelland , Surya Ganguli

This survey provides a comprehensive review on recent advancements of generative learning models in robotic manipulation, addressing key challenges in the field. Robotic manipulation faces critical bottlenecks, including significant…

We provide a theoretical analysis for end-to-end training Discrete Flow Matching (DFM) generative models. DFM is a promising discrete generative modeling framework that learns the underlying generative dynamics by training a neural network…

Machine Learning · Computer Science 2025-09-29 Maojiang Su , Mingcheng Lu , Jerry Yao-Chieh Hu , Shang Wu , Zhao Song , Alex Reneau , Han Liu

Generative Flow Networks (GFNs) have emerged as a powerful tool for sampling discrete objects from unnormalized distributions, offering a scalable alternative to Markov Chain Monte Carlo (MCMC) methods. While GFNs draw inspiration from…

Machine Learning · Computer Science 2025-02-24 Sobhan Mohammadpour , Emmanuel Bengio , Emma Frejinger , Pierre-Luc Bacon

Residual networks (Resnets) have become a prominent architecture in deep learning. However, a comprehensive understanding of Resnets is still a topic of ongoing research. A recent view argues that Resnets perform iterative refinement of…

Computer Vision and Pattern Recognition · Computer Science 2018-03-09 Stanisław Jastrzębski , Devansh Arpit , Nicolas Ballas , Vikas Verma , Tong Che , Yoshua Bengio

Generative adversarial networks (GANs) provide an algorithmic framework for constructing generative models with several appealing properties: they do not require a likelihood function to be specified, only a generating procedure; they…

Machine Learning · Statistics 2017-02-28 Shakir Mohamed , Balaji Lakshminarayanan

This book develops an effective theory approach to understanding deep neural networks of practical relevance. Beginning from a first-principles component-level picture of networks, we explain how to determine an accurate description of the…

Machine Learning · Computer Science 2022-05-31 Daniel A. Roberts , Sho Yaida , Boris Hanin

Deep generative models have made tremendous progress in modeling complex data, often exhibiting generation quality that surpasses a typical human's ability to discern the authenticity of samples. Undeniably, a key driver of this success is…

Machine Learning · Computer Science 2024-04-03 Quentin Bertrand , Avishek Joey Bose , Alexandre Duplessis , Marco Jiralerspong , Gauthier Gidel

Fitting neural networks often resorts to stochastic (or similar) gradient descent which is a noise-tolerant (and efficient) resolution of a gradient descent dynamics. It outputs a sequence of networks parameters, which sequence evolves…

Machine Learning · Statistics 2021-04-15 Gabriel Turinici

Designing plausible network models typically requires scholars to form a priori intuitions on the key drivers of network formation. Oftentimes, these intuitions are supported by the statistical estimation of a selection of network evolution…

Social and Information Networks · Computer Science 2019-07-01 Telmo Menezes , Camille Roth

Designing mRNA sequences is a major challenge in developing next-generation therapeutics, since it involves exploring a vast space of possible nucleotide combinations while optimizing sequence properties like stability, translation…

Machine Learning · Computer Science 2025-10-07 Aya Laajil , Abduragim Shtanchaev , Sajan Muhammad , Eric Moulines , Salem Lahlou

Understanding the learning dynamics of neural networks is one of the key issues for the improvement of optimization algorithms as well as for the theoretical comprehension of why deep neural nets work so well today. In this paper, we…

Machine Learning · Statistics 2021-03-18 Zhenyu Liao , Romain Couillet

A growing body of research indicates that structural plasticity mechanisms are crucial for learning and memory consolidation. Starting from a simple phenomenological model, we exploit a mean-field approach to develop a theoretical framework…

Neurons and Cognition · Quantitative Biology 2024-06-19 Gianmarco Tiddia , Luca Sergi , Bruno Golosio

The existing internet-scale image and video datasets cover a wide range of everyday objects and tasks, bringing the potential of learning policies that generalize in diverse scenarios. Prior works have explored visual pre-training with…

Robotics · Computer Science 2023-10-24 Xingyu Lin , John So , Sashwat Mahalingam , Fangchen Liu , Pieter Abbeel

Diffusion Models are popular generative modeling methods in various vision tasks, attracting significant attention. They can be considered a unique instance of self-supervised learning methods due to their independence from label…

Computer Vision and Pattern Recognition · Computer Science 2025-01-19 Michael Fuest , Pingchuan Ma , Ming Gui , Johannes Schusterbauer , Vincent Tao Hu , Bjorn Ommer

In this paper, we make the case that a scientific theory of deep learning is emerging. By this we mean a theory which characterizes important properties and statistics of the training process, hidden representations, final weights, and…