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Antibodies are proteins produced by the immune system that can identify and neutralise a wide variety of antigens with high specificity and affinity, and constitute the most successful class of biotherapeutics. With the advent of…

Biomolecules · Quantitative Biology 2024-03-27 Henry Kenlay , Frédéric A. Dreyer , Aleksandr Kovaltsuk , Dom Miketa , Douglas Pires , Charlotte M. Deane

Large language models (LLMs) show increasing potential in education, yet benchmarks for non-English languages in specialized domains remain scarce. We introduce MedBench-IT, the first comprehensive benchmark for evaluating LLMs on Italian…

Computation and Language · Computer Science 2025-09-10 Ruggero Marino Lazzaroni , Alessandro Angioi , Michelangelo Puliga , Davide Sanna , Roberto Marras

Reasoning is the fundamental capability of large language models (LLMs). Due to the rapid progress of LLMs, there are two main issues of current benchmarks: i) these benchmarks can be crushed in a short time (less than 1 year), and ii)…

Artificial Intelligence · Computer Science 2026-02-10 Chang Yang , Ruiyu Wang , Junzhe Jiang , Qi Jiang , Qinggang Zhang , Yanchen Deng , Shuxin Li , Shuyue Hu , Bo Li , Florian T. Pokorny , Xiao Huang , Xinrun Wang

As Large Language Models (LLMs) exhibit plateauing performance on conventional benchmarks, a pivotal challenge persists: evaluating their proficiency in complex, open-ended tasks characterizing genuine expert-level cognition. Existing…

We present a challenging new benchmark and learning-environment for robot learning: RLBench. The benchmark features 100 completely unique, hand-designed tasks ranging in difficulty, from simple target reaching and door opening, to longer…

Robotics · Computer Science 2019-09-27 Stephen James , Zicong Ma , David Rovick Arrojo , Andrew J. Davison

Recent advances in protein language models (PLMs) have demonstrated remarkable capabilities in understanding protein sequences. However, the extent to which different model architectures capture antibody-specific biological properties…

Machine Learning · Computer Science 2025-12-11 Mengren , Liu , Yixiang Zhang , Yiming , Zhang

When a neural language model (LM) is adapted to perform a new task, what aspects of the task predict the eventual performance of the model? In NLP, systematic features of LM generalization to individual examples are well characterized, but…

Computation and Language · Computer Science 2022-05-06 Belinda Z. Li , Jane Yu , Madian Khabsa , Luke Zettlemoyer , Alon Halevy , Jacob Andreas

As students increasingly adopt large language models (LLMs) as learning aids, it is crucial to build models that are adept at handling the nuances of tutoring: they need to identify the core needs of students, be adaptive, provide…

The emergence of various medical large language models (LLMs) in the medical domain has highlighted the need for unified evaluation standards, as manual evaluation of LLMs proves to be time-consuming and labor-intensive. To address this…

Computation and Language · Computer Science 2023-12-21 Yan Cai , Linlin Wang , Ye Wang , Gerard de Melo , Ya Zhang , Yanfeng Wang , Liang He

The LLM Agent, equipped with a code interpreter, is capable of automatically solving real-world coding tasks, such as data analysis and image editing. However, existing benchmarks primarily focus on either simplistic tasks, such as…

Software Engineering · Computer Science 2024-08-06 Yaolun Zhang , Yinxu Pan , Yudong Wang , Jie Cai

With the proliferation of Large Language Models (LLMs) in diverse domains, there is a particular need for unified evaluation standards in clinical medical scenarios, where models need to be examined very thoroughly. We present CliMedBench,…

Computation and Language · Computer Science 2024-10-07 Zetian Ouyang , Yishuai Qiu , Linlin Wang , Gerard de Melo , Ya Zhang , Yanfeng Wang , Liang He

Significant research efforts have been made to scale and improve vision-language model (VLM) training approaches. Yet, with an ever-growing number of benchmarks, researchers are tasked with the heavy burden of implementing each protocol,…

Computer Vision and Pattern Recognition · Computer Science 2024-08-12 Haider Al-Tahan , Quentin Garrido , Randall Balestriero , Diane Bouchacourt , Caner Hazirbas , Mark Ibrahim

While Large Language Models (LLMs) show significant potential in hardware engineering, current benchmarks suffer from saturation and limited task diversity, failing to reflect LLMs' performance in real industrial workflows. To address this…

Artificial Intelligence · Computer Science 2026-02-03 Zhongkai Yu , Chenyang Zhou , Yichen Lin , Hejia Zhang , Haotian Ye , Junxia Cui , Zaifeng Pan , Jishen Zhao , Yufei Ding

Protein language models (PLMs) have emerged as powerful tools to detect complex patterns of protein sequences. However, the capability of PLMs to fully capture information on protein sequences might be limited by focusing on single…

Machine Learning · Computer Science 2025-05-27 Hazem Alsamkary , Mohamed Elshaffei , Mohamed Elkerdawy , Ahmed Elnaggar

Large language models (LLMs) have significantly advanced protein representation learning. However, their capacity to interpret and design antibodies through natural language remains limited. To address this challenge, we present…

Quantitative Methods · Quantitative Biology 2026-05-21 Ling Luo , Wenbin Jiang , Hongyuan Chang , Xinkang Wang , Xushi Zhang , Yueting Xiong , Mengsha Tong , Rongshan Yu

Document content extraction is a critical task in computer vision, underpinning the data needs of large language models (LLMs) and retrieval-augmented generation (RAG) systems. Despite recent progress, current document parsing methods have…

Computer Vision and Pattern Recognition · Computer Science 2025-03-26 Linke Ouyang , Yuan Qu , Hongbin Zhou , Jiawei Zhu , Rui Zhang , Qunshu Lin , Bin Wang , Zhiyuan Zhao , Man Jiang , Xiaomeng Zhao , Jin Shi , Fan Wu , Pei Chu , Minghao Liu , Zhenxiang Li , Chao Xu , Bo Zhang , Botian Shi , Zhongying Tu , Conghui He

Multimodal language models (MLMs) show promise for clinical decision support and diagnostic reasoning, raising the prospect of end-to-end automated medical image interpretation. However, clinicians are highly selective in adopting AI tools;…

Artificial Intelligence · Computer Science 2025-08-06 Mahtab Bigverdi , Wisdom Ikezogwo , Kevin Zhang , Hyewon Jeong , Mingyu Lu , Sungjae Cho , Linda Shapiro , Ranjay Krishna

Multimodal Large Languages models have been progressing from uni-modal understanding toward unifying visual, audio and language modalities, collectively termed omni models. However, the correlation between uni-modal and omni-modal remains…

Computation and Language · Computer Science 2025-10-31 Chen Chen , ZeYang Hu , Fengjiao Chen , Liya Ma , Jiaxing Liu , Xiaoyu Li , Ziwen Wang , Xuezhi Cao , Xunliang Cai

Evaluating language models fairly is increasingly difficult as static benchmarks risk contamination by training data, obscuring whether models truly reason or recall. We introduce BeyondBench, an evaluation framework using algorithmic…

Computation and Language · Computer Science 2026-03-06 Gaurav Srivastava , Aafiya Hussain , Zhenyu Bi , Swastik Roy , Priya Pitre , Meng Lu , Morteza Ziyadi , Xuan Wang

While multimodal large language models (MLLMs) exhibit strong performance on single-video tasks (e.g., video question answering), their capability for spatiotemporal pattern reasoning across multiple videos remains a critical gap in pattern…

Computer Vision and Pattern Recognition · Computer Science 2026-01-07 Nannan Zhu , Yonghao Dong , Teng Wang , Xueqian Li , Shengjun Deng , Yijia Wang , Zheng Hong , Tiantian Geng , Guo Niu , Hanyan Huang , Xiongfei Yao , Shuaiwei Jiao
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