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Related papers: MolQAE: Quantum Autoencoder for Molecular Represen…

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Upcoming surveys will produce billions of galaxy images but comparatively few spectra, motivating models that learn cross-modal representations. We build a dataset of 134,533 galaxy images (HSC-PDR2) and spectra (DESI-DR1) and adapt a…

Instrumentation and Methods for Astrophysics · Physics 2025-10-28 Morgan Himes , Samiksha Krishnamurthy , Andrew Lizarraga , Srinath Saikrishnan , Vikram Seenivasan , Jonathan Soriano , Ying Nian Wu , Tuan Do

The ultimate goal of various fields is to directly generate molecules with desired properties, such as finding water-soluble molecules in drug development and finding molecules suitable for organic light-emitting diode (OLED) or…

Machine Learning · Computer Science 2022-02-16 Myeonghun Lee , Kyoungmin Min

Unsupervised multivariate time series (MTS) representation learning aims to extract compact and informative representations from raw sequences without relying on labels, enabling efficient transfer to diverse downstream tasks. In this…

Machine Learning · Computer Science 2025-09-22 Yi Xu , Yitian Zhang , Yun Fu

Referring Image Segmentation (RIS) aims to segment target objects expressed in natural language within a scene at the pixel level. Various recent RIS models have achieved state-of-the-art performance by generating contextual tokens to model…

Computer Vision and Pattern Recognition · Computer Science 2023-12-01 Minhyeok Lee , Dogyoon Lee , Jungho Lee , Suhwan Cho , Heeseung Choi , Ig-Jae Kim , Sangyoun Lee

Computer-driven molecular design combines the principles of chemistry, physics, and artificial intelligence to identify novel chemical compounds and materials with desired properties for a specific application. In particular,…

Chemical Physics · Physics 2023-09-04 Alessio Fallani , Leonardo Medrano Sandonas , Alexandre Tkatchenko

Molecular systems can exhibit a complex, chemically tailorable inner structure which allows for targeting of specific mechanical, electronic and optical properties. At the single-molecule level, two major complementary ways to explore these…

Mesoscale and Nanoscale Physics · Physics 2017-04-05 Rocco Gaudenzi , Maciej Misiorny , Enrique Burzurí , Maarten R. Wegewijs , Herre S. J. van der Zant

Vector Quantized Variational Autoencoders (VQ-VAEs) are fundamental models that compress continuous visual data into discrete tokens. Existing methods have tried to improve the quantization strategy for better reconstruction quality,…

Computer Vision and Pattern Recognition · Computer Science 2025-07-15 Mingkai Jia , Wei Yin , Xiaotao Hu , Jiaxin Guo , Xiaoyang Guo , Qian Zhang , Xiao-Xiao Long , Ping Tan

The de novo generation of drug-like molecules capable of inducing desirable phenotypic changes is receiving increasing attention. However, previous methods predominantly rely on expression profiles to guide molecule generation, but overlook…

Biomolecules · Quantitative Biology 2025-06-04 Hui Liu , Shiye Tian , Xuejun Liu

A challenge for molecular quantum dynamics (QD) calculations is the curse of dimensionality with respect to the nuclear degrees of freedom. A common approach that works especially well for fast reactive processes is to reduce the…

Chemical Physics · Physics 2018-01-01 Julius P. P. Zauleck , Regina de Vivie-Riedle

Identifying molecules that exhibit some pre-specified properties is a difficult problem to solve. In the last few years, deep generative models have been used for molecule generation. Deep Graph Variational Autoencoders are among the most…

Machine Learning · Computer Science 2023-06-09 Davide Rigoni , Nicolò Navarin , Alessandro Sperduti

Decoding information from bio-signals such as EEG, using machine learning has been a challenge due to the small data-sets and difficulty to obtain labels. We propose a reconstruction-based self-supervised learning model, the masked…

Signal Processing · Electrical Eng. & Systems 2022-11-07 Hsiang-Yun Sherry Chien , Hanlin Goh , Christopher M. Sandino , Joseph Y. Cheng

Self-supervised learning (SSL) enables learning useful inductive biases through utilizing pretext tasks that require no labels. The unlabeled nature of SSL makes it especially important for whole slide histopathological images (WSIs), where…

Computer Vision and Pattern Recognition · Computer Science 2022-11-15 Wisdom Oluchi Ikezogwo , Mehmet Saygin Seyfioglu , Linda Shapiro

Machine learning based methods have shown potential for optimizing existing molecules with more desirable properties, a critical step towards accelerating new chemical discovery. Here we propose QMO, a generic query-based molecule…

Machine Learning · Computer Science 2022-04-21 Samuel Hoffman , Vijil Chenthamarakshan , Kahini Wadhawan , Pin-Yu Chen , Payel Das

Is there really much more to say about sparse autoencoders (SAEs)? Autoencoders in general, and SAEs in particular, represent deep architectures that are capable of modeling low-dimensional latent structure in data. Such structure could…

Machine Learning · Computer Science 2025-06-09 Yin Lu , Xuening Zhu , Tong He , David Wipf

Artificial intelligence (AI) and machine learning (ML) are expanding in popularity for broad applications to challenging tasks in chemistry and materials science. Examples include the prediction of properties, the discovery of new reaction…

Quantum mechanics has introduced a new theoretical framework for the study of molecules, enabling the prediction of properties and dynamics through the solution of the Schr\"odinger equation applied to these systems. However, solving this…

In the intersection of molecular science and deep learning, tasks like virtual screening have driven the need for a high-throughput molecular representation generator on large chemical databases. However, as SMILES strings are the most…

Computational Engineering, Finance, and Science · Computer Science 2021-12-28 Wenhao Zhu , Ziyao Li , Lingsheng Cai , Guojie Song

The scarcity of annotated data in LiDAR point cloud understanding hinders effective representation learning. Consequently, scholars have been actively investigating efficacious self-supervised pre-training paradigms. Nevertheless, temporal…

Computer Vision and Pattern Recognition · Computer Science 2024-07-23 Weijie Wei , Fatemeh Karimi Nejadasl , Theo Gevers , Martin R. Oswald

We show that unsupervised machine learning can be used to learn physical and chemical transformation pathways from the observational microscopic data, as demonstrated for atomically resolved images in Scanning Transmission Electron…

Quantum neural networks are emerging as potential candidates to leverage noisy quantum processing units for applications. Here we introduce hybrid quantum-classical autoencoders for end-to-end radio communication. In the physical layer of…