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Training segmentation models for medical images continues to be challenging due to the limited availability of data annotations. Segment Anything Model (SAM) is a foundation model that is intended to segment user-defined objects of interest…

Computer Vision and Pattern Recognition · Computer Science 2023-08-09 Maciej A. Mazurowski , Haoyu Dong , Hanxue Gu , Jichen Yang , Nicholas Konz , Yixin Zhang

Research has focused on Multi-Modal Semantic Segmentation (MMSS), where pixel-wise predictions are derived from multiple visual modalities captured by diverse sensors. Recently, the large vision model, Segment Anything Model 2 (SAM2), has…

Computer Vision and Pattern Recognition · Computer Science 2025-03-24 Chenfei Liao , Xu Zheng , Yuanhuiyi Lyu , Haiwei Xue , Yihong Cao , Jiawen Wang , Kailun Yang , Xuming Hu

Brain tumor segmentation presents a formidable challenge in the field of Medical Image Segmentation. While deep-learning models have been useful, human expert segmentation remains the most accurate method. The recently released Segment…

Image and Video Processing · Electrical Eng. & Systems 2023-10-11 Mohammad Peivandi , Jason Zhang , Michael Lu , Dongxiao Zhu , Zhifeng Kou

Vision-Language Models (VLMs) lag behind Large Language Models due to the scarcity of annotated datasets, as creating paired visual-textual annotations is labor-intensive and expensive. To address this bottleneck, we introduce SAM2Auto, the…

Computer Vision and Pattern Recognition · Computer Science 2025-06-10 Arash Rocky , Q. M. Jonathan Wu

Vision foundation models like the Segment Anything Model (SAM), pretrained on large-scale natural image datasets, often struggle in medical image segmentation due to a lack of domain-specific adaptation. In clinical practice, fine-tuning…

Computer Vision and Pattern Recognition · Computer Science 2025-11-03 Zelin Liu , Sicheng Dong , Bocheng Li , Yixuan Yang , Jiacheng Ruan , Chenxu Zhou , Suncheng Xiang

Curating annotations for medical image segmentation is a labor-intensive and time-consuming task that requires domain expertise, resulting in "narrowly" focused deep learning (DL) models with limited translational utility. Recently,…

Computer Vision and Pattern Recognition · Computer Science 2024-03-25 Pranav Kulkarni , Adway Kanhere , Dharmam Savani , Andrew Chan , Devina Chatterjee , Paul H. Yi , Vishwa S. Parekh

Medical image segmentation has been traditionally approached by training or fine-tuning the entire model to cater to any new modality or dataset. However, this approach often requires tuning a large number of parameters during training.…

Computer Vision and Pattern Recognition · Computer Science 2024-08-14 Jay N. Paranjape , Shameema Sikder , S. Swaroop Vedula , Vishal M. Patel

The Segment Anything Model (SAM) has recently gained popularity in the field of image segmentation due to its impressive capabilities in various segmentation tasks and its prompt-based interface. However, recent studies and individual…

Computer Vision and Pattern Recognition · Computer Science 2024-01-01 Junde Wu , Wei Ji , Yuanpei Liu , Huazhu Fu , Min Xu , Yanwu Xu , Yueming Jin

Brain MR image segmentation is a key task in neuroimaging studies. It is commonly conducted using standard computational tools, such as FSL, SPM, multi-atlas segmentation etc, which are often registration-based and suffer from expensive…

Image and Video Processing · Electrical Eng. & Systems 2019-08-29 Chengliang Dai , Yuanhan Mo , Elsa Angelini , Yike Guo , Wenjia Bai

The recent Segment Anything Model 2 (SAM2) has demonstrated exceptional capabilities in interactive object segmentation for both images and videos. However, as a foundational model on interactive segmentation, SAM2 performs segmentation…

Computer Vision and Pattern Recognition · Computer Science 2025-05-05 Qiushi Yang , Yuan Yao , Miaomiao Cui , Liefeng Bo

The Segment Anything Model (SAM), a foundation model for general image segmentation, has demonstrated impressive zero-shot performance across numerous natural image segmentation tasks. However, SAM's performance significantly declines when…

Computer Vision and Pattern Recognition · Computer Science 2023-09-19 Cheng Chen , Juzheng Miao , Dufan Wu , Zhiling Yan , Sekeun Kim , Jiang Hu , Aoxiao Zhong , Zhengliang Liu , Lichao Sun , Xiang Li , Tianming Liu , Pheng-Ann Heng , Quanzheng Li

Foundation segmentation models such as SAM and SAM-2 perform well on natural images but struggle with brain MRIs where structures like the caudate and thalamus lack sharp boundaries and have low contrast. Rather than fine tune these models…

Image and Video Processing · Electrical Eng. & Systems 2025-11-26 Keith Moore

Purpose: The Segment Anything Model (SAM) promises to ease the annotation bottleneck in medical segmentation, but overlapping anatomy and blurred boundaries make its point prompts ambiguous, leading to cycles of manual refinement to achieve…

Computer Vision and Pattern Recognition · Computer Science 2026-05-25 Adrien Meyer , Lorenzo Arboit , Giuseppe Massimiani , Shih-Min Yin , Didier Mutter , Nicolas Padoy

Medical image and video segmentation is a critical task for precision medicine, which has witnessed considerable progress in developing task or modality-specific and generalist models for 2D images. However, there have been limited studies…

Image and Video Processing · Electrical Eng. & Systems 2025-04-07 Jun Ma , Zongxin Yang , Sumin Kim , Bihui Chen , Mohammed Baharoon , Adibvafa Fallahpour , Reza Asakereh , Hongwei Lyu , Bo Wang

Medical image segmentation is vital for clinical diagnosis and quantitative analysis, yet remains challenging due to the heterogeneity of imaging modalities and the high cost of pixel-level annotations. Although general interactive…

Computer Vision and Pattern Recognition · Computer Science 2026-02-24 Yujie Lu , Jingwen Li , Sibo Ju , Yanzhou Su , he yao , Yisong Liu , Min Zhu , Junlong Cheng

Intelligent medical image segmentation methods are rapidly evolving and being increasingly applied, yet they face the challenge of domain transfer, where algorithm performance degrades due to different data distributions between source and…

Computer Vision and Pattern Recognition · Computer Science 2024-08-12 Andrew Seohwan Yu , Mohsen Hariri , Xuecen Zhang , Mingrui Yang , Vipin Chaudhary , Xiaojuan Li

Segmentation is vital for ophthalmology image analysis. But its various modal images hinder most of the existing segmentation algorithms applications, as they rely on training based on a large number of labels or hold weak generalization…

Computer Vision and Pattern Recognition · Computer Science 2023-04-27 Zhongxi Qiu , Yan Hu , Heng Li , Jiang Liu

Despite that the segment anything model (SAM) achieved impressive results on general-purpose semantic segmentation with strong generalization ability on daily images, its demonstrated performance on medical image segmentation is less…

Computer Vision and Pattern Recognition · Computer Science 2024-10-03 Shizhan Gong , Yuan Zhong , Wenao Ma , Jinpeng Li , Zhao Wang , Jingyang Zhang , Pheng-Ann Heng , Qi Dou

Segment Anything Model 2 (SAM 2) serves as a core foundation model in the field of video segmentation. Building upon the original SAM model, it introduces a memory bank mechanism and demonstrates outstanding performance in tasks such as…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Zhaoyuan Ding , Yijing Yang , Han Shu , Xinghao Chen

Segment Anything Models (SAMs) have gained increasing attention in medical image analysis due to their zero-shot generalization capability in segmenting objects of unseen classes and domains when provided with appropriate user prompts.…

Computer Vision and Pattern Recognition · Computer Science 2024-12-19 Xinyuan Shao , Yiqing Shen , Mathias Unberath