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Bio-inspired computing has focused on neuron and synapses with great success. However, the connections between these, the dendrites, also play an important role. In this paper, we investigate the motivation for replicating dendritic…

Neural and Evolutionary Computing · Computer Science 2023-04-06 Daniel John Mannion , Anthony Joseph Kenyon

Neuromorphic systems seek to replicate the functionalities of biological neural networks to attain significant improvements in performance and efficiency of AI computing platforms. However, these systems have generally remained limited to…

Sophisticated machine learning struggles to transition onto battery-operated devices due to the high-power consumption of neural networks. Researchers have turned to neuromorphic engineering, inspired by biological neural networks, for more…

Neural and Evolutionary Computing · Computer Science 2023-11-23 Daniel John Mannion

This article highlights specific features of biological neurons and their dendritic trees, whose adoption may help advance artificial neural networks used in various machine learning applications. Advancements could take the form of…

Neurons and Cognition · Quantitative Biology 2021-06-15 Spyridon Chavlis , Panayiota Poirazi

Dendritic computation endows biological neurons with rich nonlinear integration and high representational capacity, yet it is largely missing in existing deep spiking neural networks (SNNs). Although detailed multi-compartment models can…

Neural and Evolutionary Computing · Computer Science 2025-12-23 Yifan Huang , Wei Fang , Zhengyu Ma , Guoqi Li , Yonghong Tian

The brain is a remarkably capable and efficient system. It can process and store huge amounts of noisy and unstructured information using minimal energy. In contrast, current artificial intelligence (AI) systems require vast resources for…

Neural and Evolutionary Computing · Computer Science 2023-06-16 Michalis Pagkalos , Roman Makarov , Panayiota Poirazi

Neurons are thought of as the building blocks of excitable brain tissue. However, at the single neuron level, the neuronal membrane, the dendritic arbor and the axonal projections can also be considered an extended active medium. Active…

Neurons and Cognition · Quantitative Biology 2013-11-28 Leonardo L. Gollo , Osame Kinouchi , Mauro Copelli

Computations on the dendritic trees of neurons have important constraints. Voltage dependent conductances in dendrites are not similar to arbitrary direct-current generation, they are the basis for dendritic nonlinearities and they do not…

Neurons and Cognition · Quantitative Biology 2021-08-12 Ilenna Simone Jones , Konrad Paul Kording

Interconnectivity, fault tolerance, and dynamic evolution of the circuitry are long sought-after objectives of bio-inspired engineering. Here, we propose dendritic transistors composed of organic semiconductors as building blocks for…

Emerging Technologies · Computer Science 2021-06-14 Matteo Cucchi , Hans Kleemann , Hsin Tseng , Alexander Lee , Karl Leo

Biological neurons are more powerful than artificial perceptrons, in part due to complex dendritic input computations. Inspired to empower the perceptron with biologically inspired features, we explore the effect of adding and tuning input…

Neural and Evolutionary Computing · Computer Science 2022-07-05 Ziwen Han , Evgeniya Gorobets , Pan Chen

Physiological experiments have highlighted how the dendrites of biological neurons can nonlinearly process distributed synaptic inputs. This is in stark contrast to units in artificial neural networks that are generally linear apart from an…

Neurons and Cognition · Quantitative Biology 2020-09-04 Ilenna Simone Jones , Konrad Paul Kording

Nanoelectronic devices emulating neuro-synaptic functionalities through their intrinsic physics at low operating energies is imperative toward the realization of brain-like neuromorphic computers. In this work, we leverage the non-linear…

Emerging Technologies · Computer Science 2021-10-13 Arnob Saha , A N M Nafiul Islam , Zijian Zhao , Shan Deng , Kai Ni , Abhronil Sengupta

How neurons process their inputs crucially determines the dynamics of biological and artificial neural networks. In such neural and neural-like systems, synaptic input is typically considered to be merely transmitted linearly or sublinearly…

Biological Physics · Physics 2017-06-01 David Breuer , Marc Timme , Raoul-Martin Memmesheimer

Analog neuromorphic computing systems emulate the parallelism and connectivity of the human brain, promising greater expressivity and energy efficiency compared to digital systems. Though many devices have emerged as candidates for…

Mesoscale and Nanoscale Physics · Physics 2023-10-05 Samuel Liu , Deji Akinwande , Dmitry Kireev , Jean Anne C. Incorvia

Our understanding of biological neuronal networks has profoundly influenced the development of artificial neural networks (ANNs). However, neurons utilized in ANNs differ considerably from their biological counterparts, primarily due to the…

Neural and Evolutionary Computing · Computer Science 2025-04-09 Xundong Wu , Pengfei Zhao , Zilin Yu , Lei Ma , Ka-Wa Yip , Huajin Tang , Gang Pan , Poirazi Panayiota , Tiejun Huang

Deep learning has seen remarkable developments over the last years, many of them inspired by neuroscience. However, the main learning mechanism behind these advances - error backpropagation - appears to be at odds with neurobiology. Here,…

Neurons and Cognition · Quantitative Biology 2018-10-29 João Sacramento , Rui Ponte Costa , Yoshua Bengio , Walter Senn

Neuron is the most important building block in our brain, and information processing in individual neuron involves the transformation of input synaptic spike trains into an appropriate output spike train. Hardware implementation of neuron…

Neurons and Cognition · Quantitative Biology 2015-06-16 Changjin Wan , Ning Liu , Ping Feng , Liqiang Zhu , Yi Shi , Qing Wan

The brain can efficiently learn a wide range of tasks, motivating the search for biologically inspired learning rules for improving current artificial intelligence technology. Most biological models are composed of point neurons, and cannot…

Neurons and Cognition · Quantitative Biology 2026-04-13 Cristiano Capone , Cosimo Lupo , Paolo Muratore , Pier Stanislao Paolucci

How neurons integrate the myriad synaptic inputs scattered across their dendrites is a fundamental question in neuroscience. Multiple neurophysiological experiments have shown that dendritic non-linearities can have a strong influence on…

Neurons and Cognition · Quantitative Biology 2025-01-13 Clarissa Lauditi , Enrico M. Malatesta , Fabrizio Pittorino , Carlo Baldassi , Nicolas Brunel , Riccardo Zecchina

Deep learning has led to significant advances in artificial intelligence, in part, by adopting strategies motivated by neurophysiology. However, it is unclear whether deep learning could occur in the real brain. Here, we show that a deep…

Neurons and Cognition · Quantitative Biology 2017-04-11 Jordan Guergiuev , Timothy P. Lillicrap , Blake A. Richards
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