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The computation power of SDN controllers fosters the development of a new generation of control plane that uses compute-intensive operations to automate and optimize the network configuration across layers. From now on, cutting-edge…

Networking and Internet Architecture · Computer Science 2016-02-05 Jérémie Leguay , Moez Draief , Symeon Chouvardas , Stefano Paris , Georgios S. Paschos , Lorenzo Maggi , Meiyu Qi

Distributed fuzzy neural networks (DFNNs) have attracted increasing attention recently due to their learning abilities in handling data uncertainties in distributed scenarios. However, it is challenging for DFNNs to handle cases in which…

Machine Learning · Computer Science 2022-10-27 Leijie Zhang , Ye Shi , Yu-Cheng Chang , Chin-Teng Lin

In this treatise we aim to build a hybrid network automated (self-adaptive) security threats discovery and prevention system; by using unconventional techniques and methods, including fuzzy logic and biological inspired algorithms under the…

Neural and Evolutionary Computing · Computer Science 2015-08-25 Mohamed Hassan

Modern autonomous systems, such as flying, legged, and wheeled robots, are generally characterized by high-dimensional nonlinear dynamics, which presents challenges for model-based safety-critical control design. Motivated by the success of…

Systems and Control · Electrical Eng. & Systems 2024-09-21 Max H. Cohen , Tamas G. Molnar , Aaron D. Ames

Biological networks exhibit intricate architectures deemed to be crucial for their functionality. In particular, gene regulatory networks, which play a key role in information processing in the cell, display non-trivial architectural…

Physics and Society · Physics 2020-02-13 Pablo Villegas , Miguel A. Muñoz , Juan A. Bonachela

Reconstruction of gene regulatory networks is the process of identifying gene dependency from gene expression profile through some computation techniques. In our human body, though all cells pose similar genetic material but the activation…

In many organisms the expression levels of each gene are controlled by the activation levels of known "Transcription Factors" (TF). A problem of considerable interest is that of estimating the "Transcription Regulation Networks" (TRN)…

Applications · Statistics 2010-11-09 Gareth M. James , Chiara Sabatti , Nengfeng Zhou , Ji Zhu

Unified understanding of neuro networks (NNs) gets the users into great trouble because they have been puzzled by what kind of rules should be obeyed to optimize the internal structure of NNs. Considering the potential capability of random…

Machine Learning · Computer Science 2022-01-03 Ruiqi Mao , Rongxin Cui

Foundation models for single-cell RNA sequencing (scRNA-seq) have shown promising capabilities in capturing gene expression patterns. However, current approaches face critical limitations: they ignore biological prior knowledge encoded in…

Machine Learning · Computer Science 2025-03-04 Mufan Qiu , Xinyu Hu , Fengwei Zhan , Sukwon Yun , Jie Peng , Ruichen Zhang , Bhavya Kailkhura , Jiekun Yang , Tianlong Chen

Many modern networks are \emph{reconfigurable}, in the sense that the topology of the network can be changed by the nodes in the network. For example, peer-to-peer, wireless and ad-hoc networks are reconfigurable. More generally, many…

Data Structures and Algorithms · Computer Science 2013-05-22 Amitabh Trehan

Software-defined networking offers numerous benefits against the legacy networking systems through simplifying the process of network management and reducing the cost of network configuration. Currently, the management of failures in the…

Networking and Internet Architecture · Computer Science 2019-04-02 Ali Malik , Benjamin Aziz , Mo Adda , Chih-Heng Ke

The potential of synthetic biology techniques for designing complex cellular circuits able to solve complicated computations opens a whole domain of exploration, beyond experiments and theory. Such cellular circuits could be used to carry…

Neurons and Cognition · Quantitative Biology 2013-10-21 Luís F. Seoane , Ricard V. Solé

Active materials take advantage of their internal sources of energy to self-organize in an automated manner. This feature provides a novel opportunity to design micron-scale machines with minimal required control. However, self-organization…

Soft Condensed Matter · Physics 2021-01-22 Zijie Qu , Jialong Jiang , Heun Jin Lee , Rob Phillips , Shahriar Shadkhoo , Matt Thomson

Identifying control strategies for biological networks is paramount for practical applications that involve reprogramming a cell's fate, such as disease therapeutics and stem cell reprogramming. Here we develop a novel network control…

Molecular Networks · Quantitative Biology 2015-08-19 Jorge G. T. Zañudo , Réka Albert

Software Defined Networking (SDN) promises greater flexibility for directing packet flows, and Network Function Virtualization promises to enable dynamic management of software-based network functions. However, the current divide between an…

Networking and Internet Architecture · Computer Science 2016-06-09 Wei Zhang , Guyue Liu , Timothy Wood , K. K. Ramakrishnan , Jinho Hwang

One of the characteristic features of genetic networks is their inherent robustness, that is, their ability to retain functionality in spite of the introduction of random errors. In this paper, we seek to better understand how robustness is…

Molecular Networks · Quantitative Biology 2009-04-29 Arnab Bhattacharyya , Bernhard Haeupler

Coregulation of the expression of groups of genes has been extensively demonstrated empirically in bacterial and eukaryotic systems. Such coregulation can arise through the use of shared regulatory motifs, which allow the coordinated…

Machine Learning · Statistics 2016-04-12 Jonathan H. Warrell , Musa M. Mhlanga

Artificial neurons built on synthetic gene networks have potential applications ranging from complex cellular decision-making to bioreactor regulation. Furthermore, due to the high information throughput of natural systems, it provides an…

Neural and Evolutionary Computing · Computer Science 2020-01-31 Sihao Huang

Software-Defined Networking (SDN) allows to control the available network resources by an intelligent and centralized authority in order to optimize traffic flows in a flexible manner. However, centralized control may face scalability…

Networking and Internet Architecture · Computer Science 2014-08-29 Benjamin J. van Asten , Niels L. M. van Adrichem , Fernando A. Kuipers

HPC systems traditionally allow their users unrestricted use of their internal network. While this network is normally controlled enough to guarantee privacy without the need for encryption, it does not provide a method to authenticate peer…

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