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While scaling laws for large language models (LLMs) during pre-training have been extensively studied, their behavior under reinforcement learning (RL) post-training remains largely unexplored. This paper presents a systematic empirical…

Aims. Clinical data indicating a heart rate (HR) target during rate control therapy for permanent atrial fibrillation (AF) and assessing its eventual relationship with reduced exercise tolerance are lacking. The present study aims at…

Medical Physics · Physics 2017-01-17 Matteo Anselmino , Stefania Scarsoglio , Andrea Saglietto , Fiorenzo Gaita , Luca Ridolfi

Video-assisted thoracoscopic surgery (VATS) is a minimally invasive surgical technique for the diagnosis and treatment of early-stage lung cancer. During VATS, large lung deformation occurs as a result of a change of patient position and a…

In this study, we utilized statistical analysis and machine learning methods to examine whether rehabilitation exercises can improve patients post-stroke functional abilities, as well as forecast the improvement in functional abilities. Our…

Volume calculation from the Computed Tomography (CT) lung lesions data is a significant parameter for clinical diagnosis. The volume is widely used to assess the severity of the lung nodules and track its progression, however, the accuracy…

Computer Vision and Pattern Recognition · Computer Science 2017-06-07 Liansheng Wang , Shusheng Li , Shuo Li

We propose a mathematical and numerical model for the simulation of the heart function that couples cardiac electrophysiology, active and passive mechanics and hemodynamics, and includes reduced models for cardiac valves and the circulatory…

Numerical Analysis · Mathematics 2022-08-12 Michele Bucelli , Alberto Zingaro , Pasquale Claudio Africa , Ivan Fumagalli , Luca Dede' , Alfio Quarteroni

Cardiovascular diseases are among the leading causes of death globally. Cardiac left ventricle (LV) quantification is known to be one of the most important tasks for the identification and diagnosis of such pathologies. In this paper, we…

Computer Vision and Pattern Recognition · Computer Science 2018-08-27 Alejandro Debus , Enzo Ferrante

The goal of this project is to use magnetic resonance imaging (MRI) data to provide an end-to-end analytics pipeline for left and right ventricle (LV and RV) segmentation. Another aim of the project is to find a model that would be…

Image and Video Processing · Electrical Eng. & Systems 2019-09-19 Bosung Seo , Daniel Mariano , John Beckfield , Vinay Madenur , Yuming Hu , Tony Reina , Marcus Bobar , Mai H. Nguyen , Ilkay Altintas

Patients with hypoplastic left heart syndrome (HLHS) are born with an underdeveloped left heart. They typically receive a sequence of surgeries that result in a single ventricle physiology called the Fontan circulation. While these patients…

Respiratory motion complicates accurate irradiation of thoraco-abdominal tumors during radiotherapy, as treatment-system latency entails target-location uncertainties. This work addresses frame forecasting in chest and liver cine MRI to…

Image and Video Processing · Electrical Eng. & Systems 2026-04-17 Michel Pohl , Mitsuru Uesaka , Hiroyuki Takahashi , Kazuyuki Demachi , Ritu Bhusal Chhatkuli

In the U.S., lung cancer is the second major cause of death. Early detection of suspicious lung nodules is crucial for patient treatment planning, management, and improving outcomes. Many approaches for lung nodule segmentation and…

Image and Video Processing · Electrical Eng. & Systems 2025-04-10 Tejas Sudharshan Mathai , Benjamin Hou , Ronald M. Summers

Computational fluid dynamics (CFD) models of blood flow in the left ventricle (LV) and aorta are important tools for analyzing the mechanistic links between myocardial deformation and flow patterns. Typically, the use of image-based…

During the radiotherapy treatment of patients with lung cancer, the radiation delivered to healthy tissue around the tumor needs to be minimized, which is difficult because of respiratory motion and the latency of linear accelerator…

Image and Video Processing · Electrical Eng. & Systems 2022-07-14 Michel Pohl , Mitsuru Uesaka , Kazuyuki Demachi , Ritu Bhusal Chhatkuli

Ejection fraction (EF) is commonly measured by echocardiography, by dividing the volume ejected by the heart (stroke volume) by the volume of the filled heart (end-diastolic volume). Utilizing volume changes of left myocardial segments per…

Medical Physics · Physics 2018-03-09 Mersedeh Karvandi , Saeed Ranjbar

Objective: This paper proposes a novel approach for automatic left ventricle (LV) quantification using convolutional neural networks (CNN). Methods: The general framework consists of one CNN for detecting the LV, and another for tissue…

Computer Vision and Pattern Recognition · Computer Science 2018-12-17 Ariel H. Curiale , Flavio D. Colavecchia , German Mato

This paper describes computer models of three interventions used for treating refractory pulmonary hypertension (RPH). These procedures create either an atrial septal defect, a ventricular septal defect, or, in the case of a Potts shunt, a…

Tissues and Organs · Quantitative Biology 2021-11-29 Seong Woo Han , Charles Puelz , Craig G. Rusin , Daniel J. Penny , Ryan Coleman , Charles S. Peskin

The choice of lung protective ventilation settings for mechanical ventilation has a considerable impact on patient outcome, yet identifying optimal ventilatory settings for individual patients remains highly challenging due to the inherent…

Lung cancer is the number one cause of cancer deaths. Many early stage lung cancer patients have resectable tumors; however, their cardiopulmonary function needs to be properly evaluated before they are deemed operative candidates.…

Computers and Society · Computer Science 2017-07-27 Oleksiy Budilovsky , Golnaz Alipour , Andre Knoesen , Lisa Brown , Soheil Ghiasi

Lumped method (Electrical analogy) is a quick and easy way to model human cardiovascular system. In this paper Lumped method is used for simulating a complete model. It describes a 36-vessel model and cardiac system of human body with…

The laboratory models of the human heart left ventricle developed in the last decades gave a valuable contribution to the comprehension of the role of the fluid dynamics in the cardiac function and to support the interpretation of the data…

Fluid Dynamics · Physics 2014-07-29 S. Fortini , G. Querzoli , S. Espa , A. Cenedese