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We present the construction of molecular force fields for small molecules (less than 25 atoms) using the recently developed symmetrized gradient-domain machine learning (sGDML) approach [Chmiela et al., Nat. Commun. 9, 3887 (2018); Sci.…

While offering unprecedented resolution of atomic and electronic structure, Scanning Probe Microscopy techniques have found greater challenges in providing reliable electrostatic characterization at the same scale. In this work, we…

The interaction of condensed phase systems with external electric fields is crucial in myriad processes in nature and technology ranging from the field-directed motion of cells (galvanotaxis), to energy storage and conversion systems…

Chemical Physics · Physics 2024-09-25 Kit Joll , Philipp Schienbein , Kevin M. Rosso , Jochen Blumberger

Oxide-water interfaces govern a wide range of physical and chemical processes fundamental to many fields like catalysis, geochemistry, corrosion, electrochemistry, and sensor technology. Near solid oxide surfaces, water behaves differently…

Chemical Physics · Physics 2025-10-31 Jan Elsner , K Nikolas Lausch , Jörg Behler

Computational Fluid Dynamics (CFD) simulations are a very important tool for many industrial applications, such as aerodynamic optimization of engineering designs like cars shapes, airplanes parts etc. The output of such simulations, in…

Computer Vision and Pattern Recognition · Computer Science 2021-03-12 Theodoros Georgiou , Sebastian Schmitt , Thomas Bäck , Nan Pu , Wei Chen , Michael Lew

Determining thermal and physical quantities across a broad temperature domain, especially up to the ultra-high temperature region, is a formidable theoretical and experimental challenge. At the same time it is essential for understanding…

Materials Science · Physics 2019-11-11 Yanhui Zhang , Alessandro Lunghi , Stefano Sanvito

In moir\'e systems, the impact of lattice relaxation on electronic band structures is significant, yet the computational demands of first-principles relaxation are prohibitively high due to the large number of atoms involved. To address…

Mesoscale and Nanoscale Physics · Physics 2025-11-25 Jiaxuan Liu , Zhong Fang , Hongming Weng , Quansheng Wu

Machine learning force fields (MLFFs), which employ neural networks to map atomic structures to system energies, effectively combine the high accuracy of first-principles calculation with the computational efficiency of empirical force…

Machine Learning · Computer Science 2025-11-17 Guangyi Dong , Zhihui Wang

Molecular dynamics simulations have been used in different scientific fields to investigate a broad range of physical systems. However, the accuracy of calculation is based on the model considered to describe the atomic interactions. In…

Statistical Mechanics · Physics 2023-02-08 Márcio S. Gomes-Filho , Alberto Torres , Alexandre Reily Rocha , Luana S. Pedroza

Reconstructing force fields (FFs) from atomistic simulation data is a challenge since accurate data can be highly expensive. Here, machine learning (ML) models can help to be data economic as they can be successfully constrained using the…

Chemical Physics · Physics 2022-10-27 Niklas Frederik Schmitz , Klaus-Robert Müller , Stefan Chmiela

Many aspects of the study of protein folding and dynamics have been affected by the recent advances in machine learning. Methods for the prediction of protein structures from their sequences are now heavily based on machine learning tools.…

Biological Physics · Physics 2019-11-25 Frank Noé , Gianni De Fabritiis , Cecilia Clementi

Machine learning force fields (MLFF) have been proposed to accelerate molecular dynamics (MD) simulation, which finds widespread applications in chemistry and biomedical research. Even for the most data-efficient MLFFs, reaching chemical…

Quantitative Methods · Quantitative Biology 2023-06-07 Alexander Bukharin , Tianyi Liu , Shengjie Wang , Simiao Zuo , Weihao Gao , Wen Yan , Tuo Zhao

We introduce a variational approximation to the microscopic dynamics of rare conformational transitions of macromolecules. Within this framework it is possible to simulate on a small computer cluster reactions as complex as protein folding,…

Soft Condensed Matter · Physics 2015-02-19 S. a Beccara , L. Fant , P. Faccioli

A multiphysics phase field model is used for the computational study of memristive thin film morphology and current-voltage hysteresis. In contrast to previous computational methods, no requirements are made on conducting filament geometry.…

Materials Science · Physics 2025-06-24 John F. Sevic , Ambroise Juston , Nobuhiko P. Kobayashi

All-atom simulations can provide molecular-level insights into the dynamics of gas-phase, condensed-phase and surface processes. One important requirement is a sufficiently realistic and detailed description of the underlying intermolecular…

Chemical Physics · Physics 2022-06-15 K. Töpfer , M. Upadhyay , M. Meuwly

The ability to accurately model interatomic interactions in large-scale systems is fundamental to understanding a wide range of physical and chemical phenomena, from drug-protein binding to the behavior of next-generation materials. While…

Materials Science · Physics 2025-05-26 Taskin Mehereen , Sourav Saha , Intesar Jawad Jaigirdar , Chanwook Park

Machine learning (ML) has emerged as a pervasive tool in science, engineering, and beyond. Its success has also led to several synergies with molecular dynamics (MD) simulations, which we use to identify and characterize the major…

Biomolecules · Quantitative Biology 2022-05-09 Christopher Kolloff , Simon Olsson

Predictive computational modeling of polymer materials is necessary for the efficient design of composite materials and the corresponding processing methods. Molecular dynamics (MD) modeling is especially important for establishing accurate…

Materials Science · Physics 2021-11-23 G. M. Odegard , S. U. Patil , P. Deshpande , K. Kanhaiya , J. Winetrout , H. Heinz , S. Shah , M. Maiaru

Numerical simulations of plasma flows are crucial for advancing our understanding of microscopic processes that drive the global plasma dynamics in fusion devices, space, and astrophysical systems. Identifying and classifying particle…

Computational Physics · Physics 2020-10-13 Stefano Markidis , Ivy Peng , Artur Podobas , Itthinat Jongsuebchoke , Gabriel Bengtsson , Pawel Herman

The particle-flow (PF) algorithm provides a global event description by reconstructing final-state particles and is central to event reconstruction in CMS. Recently, end-to-end machine learning (ML) approaches have been proposed to directly…

High Energy Physics - Experiment · Physics 2025-08-29 Farouk Mokhtar