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Quantum-classical Hybrid Machine Learning (QHML) models are recognized for their robust performance and high generalization ability even for relatively small datasets. These qualities offer unique advantages for anti-cancer drug response…

Machine Learning · Computer Science 2025-05-16 Takafumi Ito , Lysenko Artem , Tatsuhiko Tsunoda

Quantum neural networks have emerged as promising quantum machine learning models, leveraging the properties of quantum systems and classical optimization to solve complex problems in physics and beyond. However, previous studies have…

Quantum Physics · Physics 2025-06-17 Mingrui Jing , Erdong Huang , Xiao Shi , Shengyu Zhang , Xin Wang

The research explores the potential of quantum deep learning models to address challenging machine learning problems that classical deep learning models find difficult to tackle. We introduce a novel model architecture that combines…

Machine Learning · Computer Science 2023-12-05 Hao-Yuan Chen , Yen-Jui Chang , Shih-Wei Liao , Ching-Ray Chang

Representing and learning from graphs is essential for developing effective machine learning models tailored to non-Euclidean data. While Graph Neural Networks (GNNs) strive to address the challenges posed by complex, high-dimensional graph…

Quantum Physics · Physics 2025-01-15 Wenxuan Wang

In this paper, we introduce an emerging quantum machine learning (QML) framework to assist classical deep learning methods for biosignal processing applications. Specifically, we propose a hybrid quantum-classical neural network model that…

Quantum Physics · Physics 2022-10-04 Toshiaki Koike-Akino , Ye Wang

In recent years, with the development of quantum machine learning, quantum neural networks (QNNs) have gained increasing attention in the field of natural language processing (NLP) and have achieved a series of promising results. However,…

Quantum Physics · Physics 2024-05-24 Yixiong Chen , Weichuan Fang

Federated learning (FL) focuses on collaborative model training without the need to move the private data silos to a central server. Despite its several benefits, the classical FL is plagued with several limitations, such as high…

Quantum Physics · Physics 2025-10-21 Siva Sai , Abhishek Sawaika , Prabhjot Singh , Rajkumar Buyya

A novel hybrid deep neural network architecture is designed to capture the spatial-temporal features of unsteady flows around moving boundaries directly from high-dimensional unsteady flow fields data. The hybrid deep neural network is…

Computational Physics · Physics 2020-06-02 Renkun Han , Zhong Zhang , Yixing Wang , Ziyang Liu , Yang Zhang , Gang Chen

Quantum computing holds great potential for advancing the limitations of machine learning algorithms to handle higher dimensions of data and reduce overall training parameters in deep learning (DL) models. This study uses a trainable…

Quantum Physics · Physics 2023-12-05 Hao-Yuan Chen , Yen-Jui Chang , Shih-Wei Liao , Ching-Ray Chang

Hybrid quantum neural networks (HQNNs) integrate parameterized quantum circuits (PQCs) within classical networks, where the behavior of the underlying PQCs is often the primary focus of analysis. In this context, expressibility and…

Quantum Physics · Physics 2026-05-26 Muhammad Kashif , Muhammad Shafique

Accurate prediction of residue-level pKa values is essential for understanding protein function, stability, and reactivity. While existing resources such as DeepKaDB and CpHMD-derived datasets provide valuable training data, their…

Chemical Physics · Physics 2026-03-13 Van Le , Tan Le

This paper presents a hybrid quantum-classical machine learning model for classification tasks, integrating a 4-qubit quantum circuit with a classical neural network. The quantum circuit is designed to encode the features of the Iris…

Tensor Networks (TN) are approximations of high-dimensional tensors designed to represent locally entangled quantum many-body systems efficiently. This study provides a comprehensive comparison between classical TNs and TN-inspired quantum…

Quantum Physics · Physics 2022-12-20 Jack Y. Araz , Michael Spannowsky

This work focuses on designing low complexity hybrid tensor networks by considering trade-offs between the model complexity and practical performance. Firstly, we exploit a low-rank tensor-train deep neural network (TT-DNN) to build an…

Machine Learning · Computer Science 2022-03-14 Jun Qi , Chao-Han Huck Yang , Pin-Yu Chen , Javier Tejedor

One of the main challenges in drug discovery is to find molecules that bind specifically and strongly to their target protein while having minimal binding to other proteins. By predicting binding affinity, it is possible to identify the…

Quantum Physics · Physics 2023-01-19 L. Domingo , M. Djukic , C. Johnson , F. Borondo

While tensor networks have their traditional application in simulating quantum systems, in the recent decade they have gathered interest as machine learning models. We combine the experience from both fields and derive how quantum…

Quantum Physics · Physics 2026-05-05 Gustav J L Jäger , Krzysztof Bieniasz , Martin B Plenio , Hans-Martin Rieser

Full-duplex (FD) systems have been introduced to provide high data rates for beyond fifth-generation wireless networks through simultaneous transmission of information over the same frequency resources. However, the operation of FD systems…

Signal Processing · Electrical Eng. & Systems 2021-10-20 Mohamed Elsayed , Ahmad A. Aziz El-Banna , Octavia A. Dobre , Wanyi Shiu , Peiwei Wang

In the past decade, remarkable progress has been achieved in deep learning related systems and applications. In the post Moore's Law era, however, the limit of semiconductor fabrication technology along with the increasing data size have…

Quantum Physics · Physics 2022-04-04 Samuel A. Stein , Betis Baheri , Daniel Chen , Ying Mao , Qiang Guan , Ang Li , Shuai Xu , Caiwen Ding

Hybrid quantum-classical machine learning offers a path to leverage noisy intermediate-scale quantum (NISQ) devices for drug discovery, but optimal model architectures remain unclear. We systematically optimize the quantum-classical bridge…

Machine Learning · Computer Science 2025-07-28 Andrew Smith , Erhan Guven

As the rapidly evolving field of machine learning continues to produce incredibly useful tools and models, the potential for quantum computing to provide speed up for machine learning algorithms is becoming increasingly desirable. In…

Quantum Physics · Physics 2024-04-02 Anthony M. Smaldone , Gregory W. Kyro , Victor S. Batista