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Real time seizure detection is a fundamental problem in computational neuroscience towards diagnosis and treatment's improvement of epileptic disease. We propose a real-time computational method for tracking and detection of epileptic…

Quantitative Methods · Quantitative Biology 2024-06-17 Ximena Fernández , Diego Mateos

Neonatal seizures are a commonly encountered neurological condition. They are the first clinical signs of a serious neurological disorder. Thus, rapid recognition and treatment are necessary to prevent serious fatalities. The use of…

Signal Processing · Electrical Eng. & Systems 2021-12-01 Vishal Nagarajan , Ashwini Muralidharan , Deekshitha Sriraman , Pravin Kumar S

Implantable, closed-loop devices for automated early detection and stimulation of epileptic seizures are promising treatment options for patients with severe epilepsy that cannot be treated with traditional means. Most approaches for early…

In recent years, machine learning has become an increasingly powerful tool for supporting seizure detection and monitoring in epilepsy care. Traditional approaches focus on identifying seizures only after they begin, which limits the…

Machine Learning · Computer Science 2025-10-30 Ria Jayanti , Tanish Jain

Epileptic seizure forecasting, combined with the delivery of preventative therapies, holds the potential to greatly improve the quality of life for epilepsy patients and their caregivers. Forecasting seizures could prevent some potentially…

Signal Processing · Electrical Eng. & Systems 2020-05-18 Nhan Duy Truong , Yikai Yang , Christina Maher , Armin Nikpour , Omid Kavehei

Epilepsy is one of the most prevalent brain disorders that disrupts the lives of millions worldwide. For patients with drug-resistant seizures, there exist implantable devices capable of monitoring neural activity, promptly triggering…

Signal Processing · Electrical Eng. & Systems 2023-10-31 Arman Zarei , Bingzhao Zhu , Mahsa Shoaran

This study investigated the dynamic connectivity patterns between EEG and fMRI modalities, contributing to our understanding of brain network interactions. By employing a comprehensive approach that integrated static and dynamic analyses of…

Machine Learning · Computer Science 2024-12-02 Guiran Liu , Binrong Zhu

Epilepsy surgery, particularly for temporal lobe epilepsy (TLE), remains a vital treatment option for patients with drug-resistant seizures. However, accurately predicting surgical outcomes remains a significant challenge. This study…

Neurons and Cognition · Quantitative Biology 2025-07-22 Martin Guillemaud , Alice Longhena , Louis Cousyn , Valerio Frazzini , Bertrand Mathon , Vincent Navarro , Mario Chavez

Predicting post-operative seizure freedom using functional correlation networks derived from interictal intracranial EEG has shown some success. However, there are important challenges to consider. 1: electrodes physically closer to each…

Although recent studies have proposed seizure detection algorithms with good sensitivity performance, there is a remained challenge that they were hard to achieve significantly short detection latency in real-time scenarios. In this…

Signal Processing · Electrical Eng. & Systems 2023-06-29 Yankun Xu , Jie Yang , Wenjie Ming , Shuang Wang , Mohamad Sawan

Epileptic seizure detection from EEG signals remains challenging due to the high dimensionality and nonlinear, potentially stochastic, dynamics of neural activity. In this work, we investigate whether features derived from topological data…

Machine Learning · Computer Science 2026-04-15 Sunia Tanweer , Narayan Puthanmadam Subramaniyam , Firas A. Khasawneh

Neural network oscillations are a fundamental mechanism for cognition, perception and consciousness. Consequently, perturbations of network activity play an important role in the pathophysiology of brain disorders. When structural…

Neurons and Cognition · Quantitative Biology 2016-04-29 Timothée Proix , Fabrice Bartolomei , Maxime Guye , Viktor K. Jirsa

Information transmission in the human brain is a fundamentally dynamic network process. In partial epilepsy, this process is perturbed and highly synchronous seizures originate in a local network, the so-called epileptogenic zone (EZ),…

Neurons and Cognition · Quantitative Biology 2019-06-19 Simona Olmi , Spase Petkoski , Maxime Guye , Fabrice Bartolomei , Viktor Jirsa

Accurate epileptic seizure prediction from electroencephalography (EEG) remains challenging because pre-ictal dynamics may span long time horizons while clinically relevant signatures can be subtle and transient. Many deep learning models…

Machine Learning · Computer Science 2026-01-21 Tien-Dat Pham , Xuan-The Tran

Purpose: The understanding of brain activity, and in particular events such as epileptic seizures, lies on the characterisation of the dynamics of the neural networks. The theory of non-linear dynamics provides signal analysis techniques…

Medical Physics · Physics 2007-05-23 C. Silva , I. R. Pimentel , A. Andrade , J. P. Foreid , E. Ducla-Soares

The amount of power in different frequency bands of the electroencephalogram (EEG) carries information about the behavioral state of a subject. Hence, neurologists treating epileptic patients monitor the temporal evolution of the different…

Neurons and Cognition · Quantitative Biology 2020-06-17 Melisa Maidana Capitán , Nuria Cámpora , Claudio Sebastián , Sigvard Silvia Kochen , Inés Samengo

Understanding the complex interplay between the brain and a dynamic environment necessitates the continuous generation and updating of expectations for forthcoming events and their corresponding sensory and motor responses. This study…

Adaptation and Self-Organizing Systems · Physics 2023-08-24 Sina Khoonbani , Hasan Ramezanian

Epilepsy is a chronic, noncommunicable brain disorder, and sudden seizure onsets can significantly impact patients' quality of life and health. However, wearable seizure-predicting devices are still limited, partly due to the bulky size of…

Signal Processing · Electrical Eng. & Systems 2025-07-22 Ruifeng Zheng , Cong Chen , Shuang Wang , Yiming Liu , Lin You , Jindong Lu , Ruizhe Zhu , Guodao Zhang , Kejie Huang

Seizure onset detection in electroencephalography (EEG) signals is a challenging task due to the non-stereotyped seizure activities as well as their stochastic and non-stationary characteristics in nature. Joint spectral-temporal features…

Signal Processing · Electrical Eng. & Systems 2022-02-15 Xucun Yan , Dongping Yang , Zihuai Lin , Branka Vucetic

Early warning for epilepsy patients is crucial for their safety and well-being, in particular to prevent or minimize the severity of seizures. Through the patients' EEG data, we propose a meta learning framework to improve the prediction of…

Machine Learning · Computer Science 2024-01-12 Peng Zhang , Ting Gao , Jin Guo , Jinqiao Duan , Sergey Nikolenko