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Clinical trials are central to evidence-based medicine, yet many struggle to meet enrollment targets, despite the availability of over half a million trials listed on ClinicalTrials.gov, which attracts approximately two million users…

Computation and Language · Computer Science 2026-04-13 Cyrus Zhou , Yufei Jin , Yilin Xu , Yu-Chiang Wang , Chieh-Ju Chao , Monica S. Lam

Bidirectional Long Short-Term Memory Recurrent Neural Network (BLSTM-RNN) has been shown to be very effective for modeling and predicting sequential data, e.g. speech utterances or handwritten documents. In this study, we propose to use…

Computation and Language · Computer Science 2015-11-03 Peilu Wang , Yao Qian , Frank K. Soong , Lei He , Hai Zhao

Addressing the complexity of comprehensive information retrieval, this study introduces an innovative, iterative retrieval-augmented generation system. Our approach uniquely integrates a vector-space driven re-ranking mechanism with…

Information Theory · Computer Science 2024-01-04 Arash Shahmansoori

Recent advances in language models opened new opportunities to address complex schema matching tasks. Schema matching approaches have been proposed that demonstrate the usefulness of language models, but they have also uncovered important…

Databases · Computer Science 2025-06-18 Yurong Liu , Eduardo Pena , Aecio Santos , Eden Wu , Juliana Freire

Advances in single-cell sequencing have enabled high-resolution profiling of diverse molecular modalities, while integrating unpaired multi-omics single-cell data remains challenging. Existing approaches either rely on pair information or…

Quantitative Methods · Quantitative Biology 2026-01-21 Jianle Sun , Chaoqi Liang , Ran Wei , Peng Zheng , Lei Bai , Wanli Ouyang , Hongliang Yan , Peng Ye

We present HILGEN, a Hierarchically-Informed Data Generation approach that combines domain knowledge from the Unified Medical Language System (UMLS) with synthetic data generated by large language models (LLMs), specifically GPT-3.5. Our…

Computation and Language · Computer Science 2025-03-10 Yao Ge , Yuting Guo , Sudeshna Das , Swati Rajwal , Selen Bozkurt , Abeed Sarker

Standard reranking evaluations study how a reranker orders candidates returned by an upstream retriever. This setup couples ranking behavior with retrieval quality, so differences in output cannot be attributed to the ranking policy alone.…

Machine Learning · Computer Science 2026-02-24 Baris Arat , Emre Sefer

We aim to create the highest possible quality of treatment-control matches for categorical data in the potential outcomes framework. Matching methods are heavily used in the social sciences due to their interpretability, but most matching…

Machine Learning · Statistics 2019-06-11 Yameng Liu , Aw Dieng , Sudeepa Roy , Cynthia Rudin , Alexander Volfovsky

Large language models (LLMs), with advanced linguistic capabilities, have been employed in reranking tasks through a sequence-to-sequence approach. In this paradigm, multiple passages are reranked in a listwise manner and a textual reranked…

Information Retrieval · Computer Science 2024-11-08 Ruiyang Ren , Yuhao Wang , Kun Zhou , Wayne Xin Zhao , Wenjie Wang , Jing Liu , Ji-Rong Wen , Tat-Seng Chua

The Restricted Boltzmann Machine (RBM) is a stochastic neural network capable of solving a variety of difficult tasks such as NP-Hard combinatorial optimization problems and integer factorization. The RBM architecture is also very compact;…

Machine Learning · Computer Science 2020-10-15 Saavan Patel , Philip Canoza , Sayeef Salahuddin

Recognition and retrieval of textual content from the large document collections have been a powerful use case for the document image analysis community. Often the word is the basic unit for recognition as well as retrieval. Systems that…

Computer Vision and Pattern Recognition · Computer Science 2022-07-25 Siddhant Bansal , Praveen Krishnan , C. V. Jawahar

Pre-trained language models (PLMs) have proven to be effective for document re-ranking task. However, they lack the ability to fully interpret the semantics of biomedical and health-care queries and often rely on simplistic patterns for…

Computation and Language · Computer Science 2023-05-09 Deepak Gupta , Dina Demner-Fushman

Biomedical research requires large, diverse samples to produce unbiased results. Automated methods for matching variables across datasets can accelerate this process. Research in this area has been limited, primarily focusing on lexical…

Computation and Language · Computer Science 2024-11-06 Zexu Li , Suraj P. Prabhu , Zachary T. Popp , Shubhi S. Jain , Vijetha Balakundi , Ting Fang Alvin Ang , Rhoda Au , Jinying Chen

Passage retrieval addresses the problem of locating relevant passages, usually from a large corpus, given a query. In practice, lexical term-matching algorithms like BM25 are popular choices for retrieval owing to their efficiency. However,…

Information Retrieval · Computer Science 2020-09-23 Davis Liang , Peng Xu , Siamak Shakeri , Cicero Nogueira dos Santos , Ramesh Nallapati , Zhiheng Huang , Bing Xiang

Real-world classification domains, such as medicine, health and safety, and finance, often exhibit imbalanced class priors and have asynchronous misclassification costs. In such cases, the classification model must achieve a high recall…

Machine Learning · Computer Science 2021-05-11 Michał Koziarski , Colin Bellinger , Michał Woźniak

One important challenge in modern Content-Based Medical Image Retrieval (CBMIR) approaches is represented by the semantic gap, related to the complexity of the medical knowledge. Among the methods that are able to close this gap in CBMIR,…

Information Retrieval · Computer Science 2008-12-01 Roxana Teodorescu , Daniel Racoceanu , Wee-Kheng Leow , Vladimir Cretu

As large language models (LLMs) continue to advance, the need for up-to-date and well-organized benchmarks becomes increasingly critical. However, many existing datasets are scattered, difficult to manage, and make it challenging to perform…

Machine Learning · Computer Science 2025-06-03 Eunsu Kim , Haneul Yoo , Guijin Son , Hitesh Patel , Amit Agarwal , Alice Oh

We present a hybrid retrieval system for COVID-19 scientific literature, evaluated on the TREC-COVID benchmark (171,332 papers, 50 expert queries). The system implements six retrieval configurations spanning sparse (SPLADE), dense (BGE),…

Information Retrieval · Computer Science 2026-04-16 Harishkumar Kishorkumar Prajapati

Retrieval-augmented generation (RAG) is a common way to ground language models in external documents and up-to-date information. Classical retrieval systems relied on lexical methods such as BM25, which rank documents by term overlap with…

Computation and Language · Computer Science 2026-03-05 Martin Asenov , Kenza Benkirane , Dan Goldwater , Aneiss Ghodsi

Content annotation at scale remains challenging, requiring substantial human expertise and effort. This paper presents a case study in code documentation analysis, where we explore the balance between automation efficiency and annotation…

Human-Computer Interaction · Computer Science 2025-04-29 Mingyue Yuan , Jieshan Chen , Zhenchang Xing , Gelareh Mohammadi , Aaron Quigley
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