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A core aim of neurocritical care is to prevent secondary brain injury. Spreading depolarizations (SDs) have been identified as an important independent cause of secondary brain injury. SDs are usually detected using invasive…

Signal Processing · Electrical Eng. & Systems 2026-05-19 Yinzhe Wu , Sharon Jewell , Xiaodan Xing , Yang Nan , Anthony J. Strong , Guang Yang , Martyn G. Boutelle

Spreading depolarization (SD) is a self-propagating wave of near-complete neuronal depolarization that is abundant in a wide range of neurological conditions, including stroke. SD was only recently documented in humans and is now considered…

Multiple Sclerosis (MS) is a chronic autoimmune disease that can significantly reduce the quality of life of a patient. Existing treatment options can only help slow down the progression of the disease. Therefore, early detection and…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Abdul Basit , Ashir Rashid , Muhammad Abdullah Hanif , Muhammad Shafique

Electroencephalograph (EEG) timeseries signals are characterized by significant noise and coarse spatial resolution, which complicates the classification of neurodegenerative diseases. Even SOTA deep learning architectures struggle to…

Machine Learning · Computer Science 2026-05-26 Tawsik Jawad , Gowtham Atluri , Vikram Ravindra

Surface cracks are a very common indicator of potential structural faults. Their early detection and monitoring is an important factor in structural health monitoring. Left untreated, they can grow in size over time and require expensive…

Computer Vision and Pattern Recognition · Computer Science 2022-02-09 Jacob König , Mark Jenkins , Mike Mannion , Peter Barrie , Gordon Morison

Deep Learning models are easily disturbed by variations in the input images that were not seen during training, resulting in unpredictable behaviours. Such Out-of-Distribution (OOD) images represent a significant challenge in the context of…

Image and Video Processing · Electrical Eng. & Systems 2024-10-28 Benjamin Lambert , Florence Forbes , Senan Doyle , Alan Tucholka , Michel Dojat

Cortical lesions (CLs) have emerged as valuable biomarkers in multiple sclerosis (MS), offering high diagnostic specificity and prognostic relevance. However, their routine clinical integration remains limited due to subtle magnetic…

Stroke poses an immense public health burden and remains among the primary causes of death and disability worldwide. Emergent therapy is often precluded by late or indeterminate times of onset before initial clinical presentation. Rapid,…

Medical Physics · Physics 2021-04-16 Leeor Alon , Seena Dehkharghani

Brain disorders in the early and late life of humans potentially share pathological alterations in brain functions. However, the key evidence from neuroimaging data for pathological commonness remains unrevealed. To explore this hypothesis,…

Artificial Intelligence · Computer Science 2023-02-24 Mianxin Liu , Jingyang Zhang , Yao Wang , Yan Zhou , Fang Xie , Qihao Guo , Feng Shi , Han Zhang , Qian Wang , Dinggang Shen

Cortical spreading depression and spreading depolarization (CSD) are waves of neuronal depolarization that spread across the cortex, leading to a temporary saturation of brain activity. They are associated to various brain disorders such as…

Dynamical Systems · Mathematics 2023-06-16 David Reyner-Parra , Carles Bonet , Teresa M. Seara , Gemma Huguet

Hyperspectral images with high spectral resolution provide new insights into recognizing subtle differences in similar substances. However, object detection in hyperspectral images faces significant challenges in intra- and inter-class…

Computer Vision and Pattern Recognition · Computer Science 2025-12-23 Xiao He , Chang Tang , Xinwang Liu , Wei Zhang , Zhimin Gao , Chuankun Li , Shaohua Qiu , Jiangfeng Xu

Spreading depression (SD) is a wave phenomenon in gray matter tissue. Locally, it is characterized by massive re-distribution of ions across cell membranes. As a consequence, there is a sustained membrane depolarization and tissue…

Neurons and Cognition · Quantitative Biology 2014-11-18 Bas-Jan Zandt , Bennie ten Haken , Michel J. A. M. van Putten , Markus A. Dahlem

Electroencephalogram (EEG) decoding aims to identify the perceptual, semantic, and cognitive content of neural processing based on non-invasively measured brain activity. Traditional EEG decoding methods have achieved moderate success when…

Signal Processing · Electrical Eng. & Systems 2022-03-09 Xun Chen , Chang Li , Aiping Liu , Martin J. McKeown , Ruobing Qian , Z. Jane Wang

We present spatio-temporal characteristics of spreading depolarizations (SD) in two experimental systems: retracting SD wave segments observed with intrinsic optical signals in chicken retina, and spontaneously occurring re-entrant SD waves…

In cognitive radio systems, the ability to accurately detect primary user's signal is essential to secondary user in order to utilize idle licensed spectrum. Conventional energy detector is a good choice for blind signal detection, while it…

Information Theory · Computer Science 2019-09-09 Jiabao Gao , Xuemei Yi , Caijun Zhong , Xiaoming Chen , Zhaoyang Zhang

Like fingerprints, cortical folding patterns are unique to each brain even though they follow a general species-specific organization. Some folding patterns have been linked with neurodevelopmental disorders. However, due to the high…

Image and Video Processing · Electrical Eng. & Systems 2024-08-14 Louise Guillon , Joël Chavas , Audrey Bénézit , Marie-Laure Moutard , Denis Rivière , Jean-François Mangin

Resting-state EEG (rs-EEG) has been demonstrated to aid in Parkinson's disease (PD) diagnosis. In particular, the power spectral density (PSD) of low-frequency bands ({\delta} and {\theta}) and high-frequency bands ({\alpha} and \b{eta})…

Signal Processing · Electrical Eng. & Systems 2023-03-03 Anna Kurbatskaya , Alberto Jaramillo-Jimenez , John Fredy Ochoa-Gomez , Kolbjørn Brønnick , Alvaro Fernandez-Quilez

Detrended fluctuation analysis (DFA) has been used widely to determine possible long-range correlations in data obtained from diverse settings. In a recent study [1], uncorrelated random spikes superimposed on the long-range correlated…

Statistical Mechanics · Physics 2007-05-23 Radhakrishnan Nagarajan

Many current neural networks for medical imaging generalise poorly to data unseen during training. Such behaviour can be caused by networks overfitting easy-to-learn, or statistically dominant, features while disregarding other potentially…

Image and Video Processing · Electrical Eng. & Systems 2022-12-05 Joona Pohjonen , Carolin Stürenberg , Antti Rannikko , Tuomas Mirtti , Esa Pitkänen

Multiple sclerosis lesion activity segmentation is the task of detecting new and enlarging lesions that appeared between a baseline and a follow-up brain MRI scan. While deep learning methods for single-scan lesion segmentation are common,…

Computer Vision and Pattern Recognition · Computer Science 2020-06-02 Nils Gessert , Marcel Bengs , Julia Krüger , Roland Opfer , Ann-Christin Ostwaldt , Praveena Manogaran , Sven Schippling , Alexander Schlaefer
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