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Automatic segmentation of medical images is crucial in modern clinical workflows. The Segment Anything Model (SAM) has emerged as a versatile tool for image segmentation without specific domain training, but it requires human prompts and…

Computer Vision and Pattern Recognition · Computer Science 2024-05-16 Yunxiang Li , Bowen Jing , Zihan Li , Jing Wang , You Zhang

Multiplex Imaging (MI) enables the simultaneous visualization of multiple biological markers in separate imaging channels at subcellular resolution, providing valuable insights into cell-type heterogeneity and spatial organization. However,…

Image and Video Processing · Electrical Eng. & Systems 2024-11-07 Simon Gutwein , Daria Lazic , Thomas Walter , Sabine Taschner-Mandl , Roxane Licandro

Medical image segmentation is a key task in the imaging workflow, influencing many image-based decisions. Traditional, fully-supervised segmentation models rely on large amounts of labeled training data, typically obtained through manual…

Image and Video Processing · Electrical Eng. & Systems 2025-11-04 Tyler Ward , Meredith K. Owen , O'Kira Coleman , Brian Noehren , Abdullah-Al-Zubaer Imran

Segment anything model (SAM) has emerged as the leading approach for zero-shot learning in segmentation tasks, offering the advantage of avoiding pixel-wise annotations. It is particularly appealing in medical image segmentation, where the…

Image and Video Processing · Electrical Eng. & Systems 2023-12-29 Ziyi Huang , Hongshan Liu , Haofeng Zhang , Xueshen Li , Haozhe Liu , Fuyong Xing , Andrew Laine , Elsa Angelini , Christine Hendon , Yu Gan

With the growth of artificial intelligence (AI), there has been an increase in the adoption of computer vision and deep learning (DL) techniques for the evaluation of microscopy images and movies. This adoption has not only addressed…

Quantitative Methods · Quantitative Biology 2023-07-21 Binghao Chai , Christoforos Efstathiou , Haoran Yue , Viji M. Draviam

Image segmentation is fundamental to microstructural analysis for defect identification and structure-property correlation, yet remains challenging due to pronounced heterogeneity in materials images arising from varied processing and…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Sanjeev S. Navaratna , Nikhil Thawari , Gunashekhar Mari , Amritha V P , Murugaiyan Amirthalingam , Rohit Batra

Delineating farmland boundaries is essential for agricultural management such as crop monitoring and agricultural census. Traditional methods using remote sensing imagery have been efficient but limited in generalisation. The Segment…

Computer Vision and Pattern Recognition · Computer Science 2025-01-23 Yufeng Xie , Hanzhi Wu , Hongxiang Tong , Lei Xiao , Wenwen Zhou , Ling Li , Thomas Cherico Wanger

With the development of Deep Neural Networks (DNNs), many efforts have been made to handle medical image segmentation. Traditional methods such as nnUNet train specific segmentation models on the individual datasets. Plenty of recent…

Computer Vision and Pattern Recognition · Computer Science 2024-07-12 Xiaobao Wei , Jiajun Cao , Yizhu Jin , Ming Lu , Guangyu Wang , Shanghang Zhang

Recently, developing unified medical image segmentation models gains increasing attention, especially with the advent of the Segment Anything Model (SAM). SAM has shown promising binary segmentation performance in natural domains, however,…

Computer Vision and Pattern Recognition · Computer Science 2024-12-18 Shuangping Huang , Hao Liang , Qingfeng Wang , Chulong Zhong , Zijian Zhou , Miaojing Shi

Purpose: Quantitative phase imaging (QPI) is a label-free technique that provides high-contrast images of tissues and cells without the use of chemicals or dyes. Accurate semantic segmentation of cells in QPI is essential for various…

Image and Video Processing · Electrical Eng. & Systems 2024-05-13 Zhuchen Shao , Mark A. Anastasio , Hua Li

Recent advancements in artificial intelligence (AI) have precipitated a paradigm shift in medical imaging, particularly revolutionizing the domain of brain imaging. This paper systematically investigates the integration of deep learning --…

Image and Video Processing · Electrical Eng. & Systems 2024-10-18 Houze Liu , Bo Zhang , Yanlin Xiang , Yuxiang Hu , Aoran Shen , Yang Lin

Purpose: Accurate tool segmentation is essential in computer-aided procedures. However, this task conveys challenges due to artifacts' presence and the limited training data in medical scenarios. Methods that generalize to unseen data…

Computer Vision and Pattern Recognition · Computer Science 2024-02-29 Kanyifeechukwu J. Oguine , Roger D. Soberanis-Mukul , Nathan Drenkow , Mathias Unberath

Segment Anything Model (SAM), a prompt-driven foundation model for natural image segmentation, has demonstrated impressive zero-shot performance. However, SAM does not work when directly applied to medical image segmentation, since SAM…

Computer Vision and Pattern Recognition · Computer Science 2025-03-25 Bin Xie , Hao Tang , Bin Duan , Dawen Cai , Yan Yan , Gady Agam

We propose an automatic preprocessing and ensemble learning for segmentation of cell images with low quality. It is difficult to capture cells with strong light. Therefore, the microscopic images of cells tend to have low image quality but…

Image and Video Processing · Electrical Eng. & Systems 2021-08-31 Sota Kato , Kazuhiro Hotta

Accurate cell segmentation in pathology images typically requires dense pixel-wise annotations, which are costly and time-consuming to obtain. This challenge is especially important for emerging biological imaging modalities and multiplexed…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Gunjan Shrivastava , Saad Nadeem

Cell nuclei segmentation is one of the most important tasks in the analysis of biomedical images. With ever-growing sizes and amounts of three-dimensional images to be processed, there is a need for better and faster segmentation methods.…

Computer Vision and Pattern Recognition · Computer Science 2017-02-20 Julian Arz , Peter Sanders , Johannes Stegmaier , Ralf Mikut

The significant morphological and distributional variability among subcellular components poses a long-standing challenge for learning-based organelle segmentation models, significantly increasing the risk of biased feature learning.…

Computer Vision and Pattern Recognition · Computer Science 2025-07-24 Bo Fang , Jianan Fan , Dongnan Liu , Hang Chang , Gerald J. Shami , Filip Braet , Weidong Cai

Deep learning-based medical image segmentation models often suffer from domain shift, where the models trained on a source domain do not generalize well to other unseen domains. As a prompt-driven foundation model with powerful…

Image and Video Processing · Electrical Eng. & Systems 2024-07-10 Yifan Gao , Wei Xia , Dingdu Hu , Wenkui Wang , Xin Gao

This study introduces the concept of "structural beauty" as an objective computational approach for evaluating the aesthetic appeal of images. Through the utilization of the Segment anything model (SAM), we propose a method that leverages…

Computer Vision and Pattern Recognition · Computer Science 2023-11-08 Yao Qianxiang , Bin Jiang

The Segment Anything Model (SAM) exhibits a capability to segment a wide array of objects in natural images, serving as a versatile perceptual tool for various downstream image segmentation tasks. In contrast, medical image segmentation…

Computer Vision and Pattern Recognition · Computer Science 2023-08-29 Yizhe Zhang , Tao Zhou , Shuo Wang , Ye Wu , Pengfei Gu , Danny Z. Chen
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