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Reinforcement Learning with Verifiable Rewards (RLVR) significantly enhances the reasoning capability of Large Language Models (LLMs). Current RLVR approaches typically conduct training across all generated tokens, but neglect to explore…

Reinforcement Learning with Verifiable Rewards (RLVR) has proven effective for enhancing Large Language Models (LLMs) on complex reasoning tasks. However, existing methods suffer from an exploration dilemma: the sharply peaked initial…

Lead optimization in drug discovery requires efficiently navigating vast chemical space through iterative cycles to enhance molecular properties while preserving structural similarity to the original lead compound. Despite recent advances,…

Large language models (LLMs) benefit substantially from supervised fine-tuning (SFT) and reinforcement learning with verifiable rewards (RLVR) in reasoning tasks. However, these recipes perform poorly in instruction-based molecular…

The design of reliable, valid, and diverse molecules is fundamental to modern drug discovery, as improved molecular generation supports efficient exploration of the chemical space for potential drug candidates and reduces the cost of early…

Training large language models (LLMs) with reinforcement learning (RL) methods such as PPO and GRPO commonly relies on ratio clipping to stabilise updates. While effective at preventing instability, clipping discards information, introduces…

The rapid rise of synthetic media has made deepfake detection a critical challenge for online safety and trust. Progress remains constrained by the scarcity of large, high-quality datasets. Although multimodal large language models (LLMs)…

Reinforcement Learning with Verifiable Rewards (RLVR) has proven to be a highly effective strategy for endowing Large Language Models (LLMs) with robust multi-step reasoning abilities. However, its design and optimizations remain tailored…

Reinforcement learning (RL) has become a cornerstone for fine-tuning Large Language Models (LLMs), with Proximal Policy Optimization (PPO) serving as the de facto standard algorithm. Despite its ubiquity, we argue that the core ratio…

Developing new drugs is laborious and costly, demanding extensive time investment. In this paper, we introduce a de-novo drug design strategy, which harnesses the capabilities of language models to devise targeted drugs for specific…

E-commerce platforms and payment solution providers face increasingly sophisticated fraud schemes, ranging from identity theft and account takeovers to complex money laundering operations that exploit the speed and anonymity of digital…

Multimodal large language models (MLLMs) have shown promising capabilities in reasoning tasks, yet still struggle with complex problems requiring explicit self-reflection and self-correction, especially compared to their unimodal text-based…

Reinforcement learning (RL) has emerged as a powerful framework for improving the reasoning capabilities of large language models (LLMs). However, most existing RL approaches rely on sparse outcome rewards, which fail to credit correct…

Molecule generation is key to drug discovery and materials science, enabling the design of novel compounds with specific properties. Large language models (LLMs) can learn to perform a wide range of tasks from just a few examples. However,…

Using generative deep learning models and reinforcement learning together can effectively generate new molecules with desired properties. By employing a multi-objective scoring function, thousands of high-scoring molecules can be generated,…

Finetuning a Large Language Model (LLM) is crucial for generating results towards specific objectives. This research delves into the realm of drug optimization and introduce a novel reinforcement learning algorithm to finetune a drug…

Large Language Models (LLMs) can generate plausible code, but in settings that require exact stdin/stdout behavior they frequently produce programs that compile yet fail tests, and in some cases they introduce security-sensitive patterns.…

Reinforcement Learning with Verifiable Rewards (RLVR) has emerged as an effective approach for improving the reasoning abilities of large language models (LLMs). The Group Relative Policy Optimization (GRPO) family has demonstrated strong…

Deep reinforcement learning has demonstrated remarkable achievements across diverse domains such as video games, robotic control, autonomous driving, and drug discovery. Common methodologies in partially-observable domains largely lean on…

We reveal a critical yet underexplored flaw in Large Vision-Language Models (LVLMs): even when these models know the correct answer, they frequently arrive there through incorrect reasoning paths. The core issue is not a lack of knowledge,…