Related papers: ReCellTy: Domain-Specific Knowledge Graph Retrieva…
Single-cell RNA sequencing has transformed our ability to identify diverse cell types and their transcriptomic signatures. However, annotating these signatures-especially those involving poorly characterized genes-remains a major challenge.…
Reliability in cell type annotation is challenging in single-cell RNA-sequencing data analysis because both expert-driven and automated methods can be biased or constrained by their training data, especially for novel or rare cell types.…
Over the past decade, the revolution in single-cell sequencing has enabled the simultaneous molecular profiling of various modalities across thousands of individual cells, allowing scientists to investigate the diverse functions of complex…
Cell type annotation is a key task in analyzing the heterogeneity of single-cell RNA sequencing data. Although recent foundation models automate this process, they typically annotate cells independently, without considering batch-level…
This paper explores the use of large language models (LLMs) for annotating document utility in training retrieval and retrieval-augmented generation (RAG) systems, aiming to reduce dependence on costly human annotations. We address the gap…
Large language models (LLMs) and emerging agentic frameworks are beginning to transform single-cell biology by enabling natural-language reasoning, generative annotation, and multimodal data integration. However, progress remains fragmented…
Tabular data is ubiquitous in real-world applications and abundant on the web, yet its annotation has traditionally required human labor, posing a significant scalability bottleneck for tabular machine learning. Our methodology can…
Generative large language models (LLMs) can be a powerful tool for augmenting text annotation procedures, but their performance varies across annotation tasks due to prompt quality, text data idiosyncrasies, and conceptual difficulty.…
Large language models (LLMs) typically enhance their performance through either the retrieval of semantically similar information or the improvement of their reasoning capabilities. However, a significant challenge remains in effectively…
Large Language Models (LLMs) have been increasingly studied as neural knowledge bases for supporting knowledge-intensive applications such as question answering and fact checking. However, the structural organization of their knowledge…
Integrating large language models (LLMs) with knowledge graphs derived from domain-specific data represents an important advancement towards more powerful and factual reasoning. As these models grow more capable, it is crucial to enable…
While large language models (LLMs) have made significant progress in processing and reasoning over knowledge graphs, current methods suffer from a high non-retrieval rate. This limitation reduces the accuracy of answering questions based on…
Cell type annotation is critical for understanding cellular heterogeneity. Based on single-cell RNA-seq data and deep learning models, good progress has been made in annotating a fixed number of cell types within a specific tissue. However,…
Despite growing interest in using large language models (LLMs) to automate annotation, their effectiveness in complex, nuanced, and multi-dimensional labelling tasks remains relatively underexplored. This study focuses on annotation for the…
Textual data annotation, the process of labeling or tagging text with relevant information, is typically costly, time-consuming, and labor-intensive. While large language models (LLMs) have demonstrated their potential as direct…
Understanding the semantics of columns in relational tables is an important pre-processing step for indexing data lakes in order to provide rich data search. An approach to establishing such understanding is column type annotation (CTA)…
Cell type annotation is a critical yet laborious step in single-cell RNA sequencing analysis. We present a trustworthy large language model (LLM)-agent, CellTypeAgent, which integrates LLMs with verification from relevant databases.…
The unstructured nature of clinical notes within electronic health records often conceals vital patient-related information, making it challenging to access or interpret. To uncover this hidden information, specialized Natural Language…
Our work addresses the challenges of understanding tables. Existing methods often struggle with the unpredictable nature of table content, leading to a reliance on preprocessing and keyword matching. They also face limitations due to the…
Previous work has demonstrated that AI methods for analysing scientific literature benefit significantly from annotating sentences in papers according to their rhetorical roles, such as research gaps, results, limitations, extensions of…