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Early detection of newly emerging diseases, lesion severity assessment, differentiation of medical conditions and automated screening are examples for the wide applicability and importance of anomaly detection (AD) and unsupervised…

Computer Vision and Pattern Recognition · Computer Science 2025-09-17 Branko Mitic , Philipp Seeböck , Helmut Prosch , Georg Langs

Accurate detection of oral cancer is crucial for improving patient outcomes. However, the field faces two key challenges: the scarcity of deep learning-based image segmentation research specifically targeting oral cancer and the lack of…

Image and Video Processing · Electrical Eng. & Systems 2023-10-05 Ahmed Albishri , Syed Jawad Hussain Shah , Yugyung Lee , Rong Wang

In this paper, we focus on three problems in deep learning based medical image segmentation. Firstly, U-net, as a popular model for medical image segmentation, is difficult to train when convolutional layers increase even though a deeper…

Computer Vision and Pattern Recognition · Computer Science 2018-10-17 Wanli Chen , Yue Zhang , Junjun He , Yu Qiao , Yifan Chen , Hongjian Shi , Xiaoying Tang

Automatic tumor segmentation is a crucial step in medical image analysis for computer-aided diagnosis. Although the existing methods based on convolutional neural networks (CNNs) have achieved the state-of-the-art performance, many…

Image and Video Processing · Electrical Eng. & Systems 2020-05-11 Shuchao Pang , Anan Du , Mehmet A. Orgun , Yan Wang , Quanzheng Sheng , Shoujin Wang , Xiaoshui Huang , Zhemei Yu

Deep Learning (DL) approaches have been providing state-of-the-art performance in different modalities in the field of medical imagining including Digital Pathology Image Analysis (DPIA). Out of many different DL approaches, Deep…

Computer Vision and Pattern Recognition · Computer Science 2019-04-22 Md Zahangir Alom , Theus Aspiras , Tarek M. Taha , Vijayan K. Asari , TJ Bowen , Dave Billiter , Simon Arkell

Breast cancer is one of the common cancers that endanger the health of women globally. Accurate target lesion segmentation is essential for early clinical intervention and postoperative follow-up. Recently, many convolutional neural…

Image and Video Processing · Electrical Eng. & Systems 2024-01-23 Gongping Chen , Lu Zhou , Jianxun Zhang , Xiaotao Yin , Liang Cui , Yu Dai

Automatic segmentation of skin lesion is considered a crucial step in Computer Aided Diagnosis (CAD) for melanoma diagnosis. Despite its significance, skin lesion segmentation remains a challenging task due to their diverse color, texture,…

Image and Video Processing · Electrical Eng. & Systems 2020-01-27 Md. Kamrul Hasan , Lavsen Dahal , Prasad N. Samarakoon , Fakrul Islam Tushar , Robert Marti Marly

Unsupervised Anomaly Detection (UAD) plays a crucial role in identifying abnormal patterns within data without labeled examples, holding significant practical implications across various domains. Although the individual contributions of…

Machine Learning · Computer Science 2024-06-04 Zeyu Fang , Ming Gu , Sheng Zhou , Jiawei Chen , Qiaoyu Tan , Haishuai Wang , Jiajun Bu

The self-configuring nnU-Net has achieved leading performance in a large range of medical image segmentation challenges. It is widely considered as the model of choice and a strong baseline for medical image segmentation. However, despite…

Computer Vision and Pattern Recognition · Computer Science 2024-05-02 Yidong Zhao , Changchun Yang , Artur Schweidtmann , Qian Tao

Unsupervised anomaly detection (UAD) based on deep generative modelling has been increasingly explored for identifying pathological brain abnormalities without requiring voxel-level annotations. By learning the distribution of healthy…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Youwan Mahé , Elise Bannier , Stéphanie Leplaideur , Elisa Fromont , Francesca Galassi

This paper proposes an efficient solution for tumor segmentation and classification in breast ultrasound (BUS) images. We propose to add an atrous convolution layer to the conditional generative adversarial network (cGAN) segmentation model…

Image and Video Processing · Electrical Eng. & Systems 2019-07-02 Vivek Kumar Singh , Hatem A. Rashwan , Mohamed Abdel-Nasser , Md. Mostafa Kamal Sarker , Farhan Akram , Nidhi Pandey , Santiago Romani , Domenec Puig

Despite the great success of convolutional neural networks (CNN) in 3D medical image segmentation tasks, the methods currently in use are still not robust enough to the different protocols utilized by different scanners, and to the variety…

Image and Video Processing · Electrical Eng. & Systems 2022-04-21 Shrajan Bhandary , Zahra Babaiee , Dejan Kostyszyn , Tobias Fechter , Constantinos Zamboglou , Anca-Ligia Grosu , Radu Grosu

We propose a supervised anomaly detection method for data with inexact anomaly labels, where each label, which is assigned to a set of instances, indicates that at least one instance in the set is anomalous. Although many anomaly detection…

Machine Learning · Statistics 2019-09-12 Tomoharu Iwata , Machiko Toyoda , Shotaro Tora , Naonori Ueda

Medical anomaly detection is a crucial yet challenging task aimed at recognizing abnormal images to assist in diagnosis. Due to the high-cost annotations of abnormal images, most methods utilize only known normal images during training and…

Computer Vision and Pattern Recognition · Computer Science 2023-03-21 Yu Cai , Hao Chen , Xin Yang , Yu Zhou , Kwang-Ting Cheng

The emergence of tau PET imaging over the last decade has enabled Alzheimer's disease (AD) researchers to examine tau pathology in vivo and more effectively characterize the disease trajectories of AD. Current tau PET analysis methods,…

Image and Video Processing · Electrical Eng. & Systems 2025-12-16 Lujia Zhong , Shuo Huang , Jiaxin Yue , Jianwei Zhang , Zhiwei Deng , Wenhao Chi , Yonggang Shi

Obtaining models that capture imaging markers relevant for disease progression and treatment monitoring is challenging. Models are typically based on large amounts of data with annotated examples of known markers aiming at automating…

Computer Vision and Pattern Recognition · Computer Science 2017-03-20 Thomas Schlegl , Philipp Seeböck , Sebastian M. Waldstein , Ursula Schmidt-Erfurth , Georg Langs

The goal of anomaly detection is to identify anomalous samples from normal ones. In this paper, a small number of anomalies are assumed to be available at the training stage, but they are assumed to be collected only from several anomaly…

Machine Learning · Computer Science 2022-05-03 Bowen Tian , Qinliang Su , Jian Yin

Anomaly detection for Magnetic Resonance Images (MRIs) can be solved with unsupervised methods by learning the distribution of healthy images and identifying anomalies as outliers. In presence of an additional dataset of unlabelled data…

Machine Learning · Computer Science 2020-07-27 Alexandra-Ioana Albu , Alina Enescu , Luigi Malagò

Purpose: Accurate segmentation of prostate cancer on magnetic resonance (MR) images is crucial for planning image-guided interventions such as targeted biopsies, cryoablation, and radiotherapy. However, subtle and variable tumour…

Image and Video Processing · Electrical Eng. & Systems 2026-02-23 Junqing Yang , Natasha Thorley , Ahmed Nadeem Abbasi , Shonit Punwani , Zion Tse , Yipeng Hu , Shaheer U. Saeed

Pathological brain appearances may be so heterogeneous as to be intelligible only as anomalies, defined by their deviation from normality rather than any specific pathological characteristic. Amongst the hardest tasks in medical imaging,…

Image and Video Processing · Electrical Eng. & Systems 2021-02-24 Walter Hugo Lopez Pinaya , Petru-Daniel Tudosiu , Robert Gray , Geraint Rees , Parashkev Nachev , Sebastien Ourselin , M. Jorge Cardoso
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