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Optimization of pre-production vehicle configurations is one of the challenges in the automotive industry. Given a list of tests requiring cars with certain features, it is desirable to find the minimum number of cars that cover the tests…

Quantum Physics · Physics 2022-03-30 Adam Glos , Akash Kundu , Özlem Salehi

The development of tailored materials for specific applications is an active field of research in chemistry, material science and drug discovery. The number of possible molecules that can be obtained from a set of atomic species grow…

Clinical trials are pivotal in the drug discovery process to determine the safety and efficacy of a drug candidate. The high failure rates of these trials are attributed to deficiencies in clinical model development and protocol design.…

We propose a novel method for reducing the number of variables in quadratic unconstrained binary optimization problems, using a quantum annealer (or any sampler) to fix the value of a large portion of the variables to values that have a…

Quantum Physics · Physics 2017-09-26 Hamed Karimi , Gili Rosenberg

Quantum annealing is getting increasing attention in combinatorial optimization. The quantum processing unit by D-Wave is constructed to approximately solve Ising models on so-called Chimera graphs. Ising models are equivalent to quadratic…

Data Structures and Algorithms · Computer Science 2019-04-30 Michael Juenger , Elisabeth Lobe , Petra Mutzel , Gerhard Reinelt , Franz Rendl , Giovanni Rinaldi , Tobias Stollenwerk

The recent availability of quantum annealers as cloud-based services has enabled new ways to handle machine learning problems, and several relevant algorithms have been adapted to run on these devices. In a recent work, linear regression…

Quantum Physics · Physics 2025-03-18 Costantino Carugno , Maurizio Ferrari Dacrema , Paolo Cremonesi

With the advent of exascale computing, effective load balancing in massively parallel software applications is critically important for leveraging the full potential of high performance computing systems. Load balancing is the distribution…

Quantum Physics · Physics 2025-01-30 Omer Rathore , Alastair Basden , Nicholas Chancellor , Halim Kusumaatmaja

The Minimum Bisection Problem is a well-known NP-hard problem in combinatorial optimization, with practical applications in areas such as parallel computing, network design, and machine learning. In this paper, we examine the potential of…

Quantum Physics · Physics 2025-09-24 Renáta Rusnáková , Martin Chovanec , Juraj Gazda

Quantum computers are becoming more mainstream. As more programmers are starting to look at writing quantum programs, they need to test and debug their code. In this paper, we discuss various use-cases for quantum computers, either…

Software Engineering · Computer Science 2021-03-17 Andriy Miranskyy , Lei Zhang , Javad Doliskani

Optimization of electricity surplus is a crucial element for transmission power networks to reduce costs and efficiently use the available electricity across the network. In this paper we showed how to optimize such a network with quantum…

Quantum Physics · Physics 2022-12-06 Giuseppe Colucci , Stan van der Linde , Frank Phillipson

With progress in quantum technology more sophisticated quantum annealing devices are becoming available. While they offer new possibilities for solving optimization problems, their true potential is still an open question. As the optimal…

Quantum Physics · Physics 2017-02-22 Bettina Heim , Ethan W. Brown , Dave Wecker , Matthias Troyer

We solve a multi-period portfolio optimization problem using D-Wave Systems' quantum annealer. We derive a formulation of the problem, discuss several possible integer encoding schemes, and present numerical examples that show high success…

Computational Finance · Quantitative Finance 2016-09-29 Gili Rosenberg , Poya Haghnegahdar , Phil Goddard , Peter Carr , Kesheng Wu , Marcos López de Prado

In recent years, quantum, quantum-inspired, and hybrid algorithms are increasingly showing promise for solving software engineering optimization problems. However, best-intended practices for conducting empirical studies have not yet well…

Software Engineering · Computer Science 2025-11-03 Man Zhang , Yuechen Li , Tao Yue , Kai-Yuan Cai

High-energy physics is replete with hard computational problems and it is one of the areas where quantum computing could be used to speed up calculations. We present an implementation of likelihood-based regularized unfolding on a quantum…

Data Analysis, Statistics and Probability · Physics 2020-10-09 Kyle Cormier , Riccardo Di Sipio , Peter Wittek

In this paper, we explore the potential for quantum annealing to solve realistic routing problems. We focus on two NP-Hard problems, including the Traveling Salesman Problem with Time Windows and the Capacitated Vehicle Routing Problem with…

Emerging Technologies · Computer Science 2025-04-01 James B. Holliday , Darren Blount , Eneko Osaba , Khoa Luu

Portfolio optimization is one of the most studied problems for demonstrating the near-term applications of quantum computing. However, large-scale problems cannot be solved on today's quantum hardware. In this work, we extend upon a study…

Quantum Physics · Physics 2023-05-03 Naman Jain , M Girish Chandra

We propose a modified quantum annealing protocol, i. e., pulsed quantum annealing} (PQA), in order to increase the success probability by a pulse application during the quantum annealing process. It is well known that the success…

Quantum Physics · Physics 2020-08-18 Vasilios Karanikolas , Shiro Kawabata

The protocol of quantum annealing is applied to an optimization problem with a one-dimensional continuous degree of freedom, a variant of the problem proposed by Shinomoto and Kabashima. The energy landscape has a number of local minima,…

Quantum Physics · Physics 2022-06-23 Yang Wei Koh , Hidetoshi Nishimori

Using Quantum Computers to solve problems in Recommender Systems that classical computers cannot address is a worthwhile research topic. In this paper, we use Quantum Annealers to address the feature selection problem in recommendation…

Information Retrieval · Computer Science 2024-07-04 Jiayang Niu , Jie Li , Ke Deng , Yongli Ren

We propose and implement modern computational methods to enhance catastrophe excess-of-loss reinsurance contracts in practice. The underlying optimization problem involves attachment points, limits, and reinstatement clauses, and the…