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Recent advances bring within reach the viability of solving combinatorial problems using a quantum annealing algorithm implemented on a purpose-built platform that exploits quantum properties. However, the question of how to tune the…

Data Structures and Algorithms · Computer Science 2014-10-21 Andrew D. King , Catherine C. McGeoch

Conformation generation, also known as molecular unfolding (MU), is a crucial step in structure-based drug design, remaining a challenging combinatorial optimization problem. Quantum annealing (QA) has shown great potential for solving…

Principal component analysis is commonly used for dimensionality reduction, feature extraction, denoising, and visualization. The most commonly used principal component analysis method is based upon optimization of the L2-norm, however, the…

Emerging Technologies · Computer Science 2025-01-28 Ian Tomeo , Panos P. Markopoulos , Andreas Savakis

Current quantum annealing (QA) hardware suffers from practical limitations such as finite temperature, sparse connectivity, small qubit numbers, and control error. We propose new algorithms for mapping boolean constraint satisfaction…

Quantum Physics · Physics 2016-03-11 Zhengbing Bian , Fabian Chudak , Robert Israel , Brad Lackey , William G. Macready , Aidan Roy

In this article, we show how to map a sampling of the hardest artificial intelligence problems in space exploration onto equivalent Ising models that then can be attacked using quantum annealing implemented in D-Wave machine. We overview…

Many problems of industrial interest are NP-complete, and quickly exhaust resources of computational devices with increasing input sizes. Quantum annealers (QA) are physical devices that aim at this class of problems by exploiting quantum…

Quantum phenomena have the potential to speed up the solution of hard optimization problems. For example quantum annealing, based on the quantum tunneling effect, has recently been shown to scale exponentially better with system size as…

Quantum Physics · Physics 2017-04-27 Simon E. Nigg , Niels Loerch , Rakesh P. Tiwari

This work proposes a hybrid framework combining classical computers with quantum annealers for structural optimisation. At each optimisation iteration of an iterative process, two minimisation problems are formulated one for the underlying…

Computational Engineering, Finance, and Science · Computer Science 2025-10-27 Van-Dung Nguyen , Erin Kuci , Michel Rasquin , Ludovic Noels

We review here the recent success in quantum annealing, i.e., optimization of the cost or energy functions of complex systems utilizing quantum fluctuations. The concept is introduced in successive steps through the studies of mapping of…

Quantum Physics · Physics 2010-09-21 Arnab Das , Bikas K. Chakrabarti

Quantum computers have the potential of solving problems more efficiently than classical computers. While first commercial prototypes have become available, the performance of such machines in practical application is still subject to…

Emerging Technologies · Computer Science 2020-05-13 Tom Krüger , Wolfgang Mauerer

Quantum computing holds the promise of substantially speeding up computationally expensive tasks, such as solving optimization problems over a large number of elements. In high-energy collider physics, quantum-assisted algorithms might…

Quantum Physics · Physics 2022-11-23 Andrea Delgado , Jesse Thaler

This paper explores the applications of quantum annealing (QA) and classical simulated annealing (SA) to a suite of combinatorial optimization problems in machine learning, namely feature selection, instance selection, and clustering. We…

Quantum Physics · Physics 2025-07-22 Chloe Pomeroy , Aleksandar Pramov , Karishma Thakrar , Lakshmi Yendapalli

In the current NISQ-era, one of the major challenges faced by researchers and practitioners lies in figuring out how to combine quantum and classical computing in the most efficient and innovative way. In this paper, we present a mechanism…

Emerging Technologies · Computer Science 2024-10-02 Eneko Osaba , Esther Villar-Rodriguez , Antón Asla

We propose Quantum Enhanced Simulated Annealing (QESA), a novel hybrid optimization framework that integrates quantum annealing (QA) into simulated annealing (SA) to tackle continuous optimization problems. While QA has shown promise in…

Quantum Physics · Physics 2025-04-04 Hristo N. Djidjev

The major advances in quantum computing over the last few decades have sparked great interest in applying it to solve the most challenging computational problems in a wide variety of areas. One of the most pronounced domains here are…

Quantum Physics · Physics 2024-04-11 Andreas Sturm , Bharadwaj Mummaneni , Leon Rullkötter

Recent demonstrations on specialized benchmarks have reignited excitement for quantum computers, yet whether they can deliver an advantage for practical real-world problems remains an open question. Here, we show that probabilistic…

Quantum computing, along with quantum metrology and quantum communication, are disruptive technologies that promise, in the near future, to impact different sectors of academic research and industry. Among the computational challenges with…

Quantum computing is emerging as a new computing resource that could be superior to conventional computing for certain classes of optimization problems. However, in principle, most existing approaches to quantum optimization are intended to…

Optimization and Control · Mathematics 2022-01-21 Chin-Yao Chang , Eric Jones , Yiyun Yao , Peter Graf , Rishabh Jain

Quantum computing has demonstrated the potential to solve computationally intensive problems more efficiently than classical methods. Many software engineering tasks, such as test case selection, static analysis, code clone detection, and…

Software Engineering · Computer Science 2025-06-10 Jianjun Zhao

In the rapidly advancing domain of quantum optimization, the confluence of quantum algorithms such as Quantum Annealing (QA) and the Quantum Approximate Optimization Algorithm (QAOA) with robust optimization methodologies presents a…

Quantum Physics · Physics 2024-05-14 Pascal Halffmann , Steve Lenk , Michael Trebing
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