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Some patients benefit from a treatment while others may do so less or do not benefit at all. We have previously developed a two-stage network meta-regression prediction model that synthesized randomized trials and evaluates how treatment…

Predicting the chemical properties of compounds is crucial in discovering novel materials and drugs with specific desired characteristics. Recent significant advances in machine learning technologies have enabled automatic predictive…

Quantitative Methods · Quantitative Biology 2021-12-10 Yang Liu , Hisashi Kashima

Ordinal user-provided ratings across multiple items are frequently encountered in both scientific and commercial applications. Whilst recommender systems are known to do well on these type of data from a predictive point of view, their…

Methodology · Statistics 2025-03-05 Sjoerd Hermes

Results in epidemiology and social science often require the removal of confounding effects from measurements of the pairwise correlation of variables in survey data. This is typically accomplished by some variant of linear regression…

Methodology · Statistics 2025-12-02 William H. Press

Data analysis based on information from several sources is common in economic and biomedical studies. This setting is often referred to as the data fusion problem, which differs from traditional missing data problems since no complete data…

Methodology · Statistics 2022-04-07 Wei Li , Shanshan Luo , Wangli Xu

There have been many claims in the media and a bit of respectable research about the causes of variation in firearm sales. The challenges for causal inference can be quite daunting. This paper reports an analysis of daily handgun sales in…

Methodology · Statistics 2021-05-25 Richard A. Berk

When an item goes out of stock, sales transaction data no longer reflect the original customer demand, since some customers leave with no purchase while others substitute alternative products for the one that was out of stock. Here we…

Applications · Statistics 2016-01-15 Benjamin Letham , Lydia M. Letham , Cynthia Rudin

We present a new procedure for enhanced variable selection for component-wise gradient boosting. Statistical boosting is a computational approach that emerged from machine learning, which allows to fit regression models in the presence of…

Many commercial products are sold with warranties and indirectly through dealers. The manufacturer-retailer distribution mechanism results in serious missing data problems in field return data, as the sales date for an unreturned unit is…

Applications · Statistics 2014-12-04 Zhisheng Ye , Hon Keung Tony Ng

We interpret multi-product supply chains (SCs) as coordinated markets; under this interpretation, a SC optimization problem is a market clearing problem that allocates resources and associated economic values (prices) to different…

Optimization and Control · Mathematics 2020-07-03 Philip A. Tominac , Victor M. Zavala

Time-series forecasting is an important task in both academic and industry, which can be applied to solve many real forecasting problems like stock, water-supply, and sales predictions. In this paper, we study the case of retailers' sales…

Machine Learning · Computer Science 2020-02-28 Chaochao Chen , Ziqi Liu , Jun Zhou , Xiaolong Li , Yuan Qi , Yujing Jiao , Xingyu Zhong

This paper proposes data mining techniques to model the return on investment from various types of promotional spending to market a drug and then uses the model to draw conclusions on how the pharmaceutical industry might go about…

Statistics Theory · Mathematics 2014-04-01 Dominique Haughton , Guangying Hua , Danny Jin , John Lin , Qizhi Wei , Changan Zhang

Diabetes is a chronic metabolic disease characterized by elevated blood glucose levels, leading to complications like heart disease, kidney failure, and nerve damage. Accurate state-level predictions are vital for effective healthcare…

Machine Learning · Computer Science 2025-06-18 Vuong M. Ngo , Tran Quang Vinh , Patricia Kearney , Mark Roantree

The use of drug combinations, termed polypharmacy, is common to treat patients with complex diseases and co-existing conditions. However, a major consequence of polypharmacy is a much higher risk of adverse side effects for the patient.…

Machine Learning · Computer Science 2018-08-15 Marinka Zitnik , Monica Agrawal , Jure Leskovec

Binomial data with unknown sizes often appear in biological and medical sciences and are usually overdispersed. All previous methods used parametric models and only considered overdispersion due to the variation of sizes. The proposed…

Statistics Theory · Mathematics 2007-06-13 Wei Zhang

Software Product Lines (SPL) are inherently difficult to test due to the combinatorial explosion of the number of products to consider. To reduce the number of products to test, sampling techniques such as combinatorial interaction testing…

Software Engineering · Computer Science 2017-10-24 Xavier Devroey , Maxime Cordy , Gilles Perrouin , Pierre-Yves Schobbens , Axel Legay , Patrick Heymans

We present a data augmentation scheme to perform Markov chain Monte Carlo inference for models where data generation involves a rejection sampling algorithm. Our idea, which seems to be missing in the literature, is a simple scheme to…

Computation · Statistics 2015-08-04 Vinayak Rao , Lizhen Lin , David Dunson

Pharmaceutical targeting is one of key inputs for making sales and marketing strategy planning. Targeting list is built on predicting physician's sales potential of certain type of patient. In this paper, we present a time-sensitive…

Machine Learning · Computer Science 2018-12-04 Weiyu Huang , Yunlong Wang , Li Zhou , Emily Zhao , Yilian Yuan , Alejandro Ribero

Linear causal analysis is central to a wide range of important application spanning finance, the physical sciences, and engineering. Much of the existing literature in linear causal analysis operates in the time domain. Unfortunately, the…

Machine Learning · Computer Science 2016-03-11 Francois W. Belletti , Evan R. Sparks , Michael J. Franklin , Alexandre M. Bayen , Joseph E. Gonzalez

This paper investigates a multi-product stochastic inventory problem in which a cash-constrained online retailer can adopt order-based loan provided by some Chinese e-commerce platforms to speed up its cash recovery for deferred revenue. We…

Optimization and Control · Mathematics 2020-12-10 Zhen Chen , Ren-qian Zhang