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Large language models (LLMs) inevitably make mistakes when performing step-by-step mathematical reasoning. Process Reward Models (PRMs) have emerged as a promising solution by evaluating each reasoning step. However, existing PRMs typically…

Computation and Language · Computer Science 2025-03-28 Shuaijie She , Junxiao Liu , Yifeng Liu , Jiajun Chen , Xin Huang , Shujian Huang

Accurate preoperative assessment of lymph node (LN) metastasis in rectal cancer guides treatment decisions, yet conventional MRI evaluation based on morphological criteria shows limited diagnostic performance. While some artificial…

Machine Learning · Computer Science 2025-07-16 Yaoxian Dong , Yifan Gao , Haoyue Li , Yanfen Cui , Xin Gao

Recent advances in general medical AI have made significant strides, but existing models often lack the reasoning capabilities needed for complex medical decision-making. This paper presents GMAI-VL-R1, a multimodal medical reasoning model…

Computer Vision and Pattern Recognition · Computer Science 2025-04-03 Yanzhou Su , Tianbin Li , Jiyao Liu , Chenglong Ma , Junzhi Ning , Cheng Tang , Sibo Ju , Jin Ye , Pengcheng Chen , Ming Hu , Shixiang Tang , Lihao Liu , Bin Fu , Wenqi Shao , Xiaowei Hu , Xiangwen Liao , Yuanfeng Ji , Junjun He

The growing integration of vision-language models (VLMs) in medical applications offers promising support for diagnostic reasoning. However, current medical VLMs often face limitations in generalization, transparency, and computational…

Computer Vision and Pattern Recognition · Computer Science 2025-06-17 Tan-Hanh Pham , Chris Ngo

The integration of Large Language Models (LLMs) into healthcare is constrained by knowledge limitations, hallucinations, and a disconnect from Evidence-Based Medicine (EBM). While Retrieval-Augmented Generation (RAG) offers a solution,…

Computation and Language · Computer Science 2026-02-03 Qiaoyu Zheng , Yuze Sun , Chaoyi Wu , Weike Zhao , Pengcheng Qiu , Yongguo Yu , Kun Sun , Jian Zhang , Yanfeng Wang , Ya Zhang , Weidi Xie

Interpretation is critical for disease diagnosis, but existing models struggle to balance predictive accuracy with human-understandable rationales. While large language models (LLMs) offer strong reasoning abilities, their clinical use is…

Computation and Language · Computer Science 2025-07-15 Shuai Niu , Jing Ma , Hongzhan Lin , Liang Bai , Zhihua Wang , Yida Xu , Yunya Song , Xian Yang

Recent multimodal large language models (MLLMs) achieve strong performance on visual reasoning benchmarks, yet it remains unclear to what extent such performance reflects reasoning directly grounded in visual evidence. We introduce…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Longteng Guo , Yifan Wang , Pengkang Huo , Tailai Chen , Yuze Wu , Jing Liu , Xinxin Zhu

Reasoning has substantially improved the performance of large language models (LLMs) on complicated tasks. Central to the current reasoning studies, Process Reward Models (PRMs) offer a fine-grained evaluation of intermediate reasoning…

Machine Learning · Computer Science 2025-11-05 Qi Cao , Ruiyi Wang , Ruiyi Zhang , Sai Ashish Somayajula , Pengtao Xie

Mental health disorders affect hundreds of millions globally, and the Web now serves as a primary medium for accessing support, information, and assessment. Large language models (LLMs) offer scalable and accessible assistance, yet their…

Multimodal large language models (MLLMs) have achieved remarkable progress on vision-language tasks, yet their reasoning processes remain sometimes unreliable. We introduce PRISM-Bench, a benchmark of puzzle-based visual challenges designed…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Yusu Qian , Cheng Wan , Chao Jia , Yinfei Yang , Qingyu Zhao , Zhe Gan

Medical diagnosis is not a single prediction from a fully specified vignette. It is a sequential workup: clinicians decide what evidence to obtain, revise a differential diagnosis, and stop when the diagnosis is sufficiently supported. Most…

Computer Vision and Pattern Recognition · Computer Science 2026-05-25 Jiazhen Pan , Weixiang Shen , Jun Li , Julian Canisius , Felix Bitzer , Paula Roßmüller , Jiancheng Yang , Virginie Kreutzinger , Daniel Rueckert , Benedikt Wiestler

Large language models (LLMs) offer a promising pre-screening tool, improving early disease detection and providing enhanced healthcare access for underprivileged communities. The early diagnosis of various diseases continues to be a…

Artificial Intelligence · Computer Science 2025-04-10 Umakanta Maharana , Sarthak Verma , Avarna Agarwal , Prakashini Mruthyunjaya , Dwarikanath Mahapatra , Sakir Ahmed , Murari Mandal

Test-time scaling has significantly improved large language model performance, enabling deeper reasoning to solve complex problems. However, this increased reasoning capability also leads to excessive token generation and unnecessary…

Evaluating generated radiology reports is crucial for the development of radiology AI, but existing metrics fail to reflect the task's clinical requirements. This study proposes a novel evaluation framework using large language models…

Computation and Language · Computer Science 2024-04-02 Zilong Wang , Xufang Luo , Xinyang Jiang , Dongsheng Li , Lili Qiu

Vision-language models (VLM) have markedly advanced AI-driven interpretation and reporting of complex medical imaging, such as computed tomography (CT). Yet, existing methods largely relegate clinicians to passive observers of final…

The diagnosis of pathological images is often limited by expert availability and regional disparities, highlighting the importance of automated diagnosis using Vision-Language Models (VLMs). Traditional multimodal models typically emphasize…

Computer Vision and Pattern Recognition · Computer Science 2025-04-21 Jianyu Wu , Hao Yang , Xinhua Zeng , Guibing He , Zhiyu Chen , Zihui Li , Xiaochuan Zhang , Yangyang Ma , Run Fang , Yang Liu

Chain-of-Thought (CoT) reasoning has proven effective in enhancing large language models by encouraging step-by-step intermediate reasoning, and recent advances have extended this paradigm to Multimodal Large Language Models (MLLMs). In the…

Image and Video Processing · Electrical Eng. & Systems 2026-03-24 Juntao Jiang , Jiangning Zhang , Yali Bi , Jinsheng Bai , Weixuan Liu , Weiwei Jin , Zhucun Xue , Yong Liu , Xiaobin Hu , Shuicheng Yan

Large Language Models (LLMs) have exhibited remarkable capabilities in clinical scenarios. Despite their potential, existing works face challenges when applying LLMs to medical settings. Strategies relying on training with medical datasets…

Computation and Language · Computer Science 2025-10-10 Keer Lu , Zheng Liang , Da Pan , Shusen Zhang , Guosheng Dong , Zhonghai Wu , Huang Leng , Bin Cui , Wentao Zhang

Multimodal medical large language models have shown substantial progress in chest X-ray interpretation but continue to face challenges in spatial reasoning and anatomical understanding. Although existing grounding techniques improve overall…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Anees Ur Rehman Hashmi , Numan Saeed , Christoph Lippert

Large Language Models (LLMs) have been shown to encode clinical knowledge. Many evaluations, however, rely on structured question-answer benchmarks, overlooking critical challenges of interpreting and reasoning about unstructured clinical…

Computation and Language · Computer Science 2026-04-01 Meghal Dani , Muthu Jeyanthi Prakash , Filip Rosa , Zeynep Akata , Stefanie Liebe