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Identifying subgroups, which respond differently to a treatment, both in terms of efficacy and safety, is an important part of drug development. A well-known challenge in exploratory subgroup analyses is the small sample size in the…

Computation · Statistics 2016-06-28 Marius Thomas , Björn Bornkamp

Neural networks produced by standard training are known to suffer from poor accuracy on rare subgroups despite achieving high accuracy on average, due to the correlations between certain spurious features and labels. Previous approaches…

Machine Learning · Computer Science 2024-04-10 Gaotang Li , Jiarui Liu , Wei Hu

Identifying and making statistical inferences on differential treatment effects (commonly known as subgroup analysis in clinical research) is central to precision health. Subgroup analysis allows practitioners to pinpoint populations for…

Machine Learning · Statistics 2026-02-05 Zhongming Xie , Joseph Giorgio , Jingshen Wang

By exploiting double-penalty terms for the primal subproblem, we develop a novel relaxed augmented Lagrangian method for solving a family of convex optimization problems subject to equality or inequality constraints. The method is then…

Numerical Analysis · Mathematics 2025-06-16 Jianchao Bai , Linyuan Jia , Zheng Peng

We present a new feasible proximal gradient method for constrained optimization where both the objective and constraint functions are given by the summation of a smooth, possibly nonconvex function and a convex simple function. The…

Optimization and Control · Mathematics 2024-02-01 Digvijay Boob , Qi Deng , Guanghui Lan

Attention to data-driven optimization approaches, including the well-known stochastic gradient descent method, has grown significantly over recent decades, but data-driven constraints have rarely been studied, because of the computational…

Machine Learning · Computer Science 2023-10-11 Shuoguang Yang , Xudong Li , Guanghui Lan

This paper introduces a novel approach to system identification for nonlinear input-output models that minimizes the simulation error and frames the problem as a constrained optimization task. The proposed method addresses vanishing…

Optimization and Control · Mathematics 2025-12-17 Vito Cerone , Sophie M. Fosson , Simone Pirrera , Diego Regruto

In this paper, we study a fixed-confidence, fixed-tolerance formulation of a class of stochastic bi-level optimization problems, where the upper-level problem selects from a finite set of systems based on a performance metric, and the…

Optimization and Control · Mathematics 2025-01-20 Yuhao Wang , Seong-Hee Kim , Enlu Zhou

This study focuses on solving group zero-norm regularized robust loss minimization problems. We propose a proximal Majorization-Minimization (PMM) algorithm to address a class of equivalent Difference-of-Convex (DC) surrogate optimization…

Optimization and Control · Mathematics 2025-05-30 Ling Liang , Shujun Bi

We propose a framework for modeling and solving low-rank optimization problems to certifiable optimality. We introduce symmetric projection matrices that satisfy $Y^2=Y$, the matrix analog of binary variables that satisfy $z^2=z$, to model…

Optimization and Control · Mathematics 2021-12-22 Dimitris Bertsimas , Ryan Cory-Wright , Jean Pauphilet

Global optimization of decision trees is a long-standing challenge in combinatorial optimization, yet such models play an important role in interpretable machine learning. Although the problem has been investigated for several decades, only…

Machine Learning · Computer Science 2026-02-03 Jiancheng Tu , Wenqi Fan , Zhibin Wu

We consider (stochastic) subgradient methods for strongly convex but potentially nonsmooth non-Lipschitz optimization. We provide new equivalent dual descriptions (in the style of dual averaging) for the classic subgradient method, the…

Optimization and Control · Mathematics 2024-12-31 Benjamin Grimmer , Danlin Li

This study develops a framework for a class of constant modulus (CM) optimization problems, which covers binary constraints, discrete phase constraints, semi-orthogonal matrix constraints, non-negative semi-orthogonal matrix constraints,…

Signal Processing · Electrical Eng. & Systems 2024-11-12 Junbin Liu , Ya Liu , Wing-Kin Ma , Mingjie Shao , Anthony Man-Cho So

Compressive sensing (CS) reconstructs images from sub-Nyquist measurements by solving a sparsity-regularized inverse problem. Traditional CS solvers use iterative optimizers with hand crafted sparsifiers, while early data-driven methods…

Computer Vision and Pattern Recognition · Computer Science 2023-06-02 Pamuditha Somarathne , Tharindu Wickremasinghe , Amashi Niwarthana , A. Thieshanthan , Chamira U. S. Edussooriya , Dushan N. Wadduwage

Prior work has shown that Visual Recognition datasets frequently underrepresent bias groups $B$ (\eg Female) within class labels $Y$ (\eg Programmers). This dataset bias can lead to models that learn spurious correlations between class…

Computer Vision and Pattern Recognition · Computer Science 2023-04-28 Maan Qraitem , Kate Saenko , Bryan A. Plummer

We introduce a new method for estimating the mean of an outcome variable within groups when researchers only observe the average of the outcome and group indicators across a set of aggregation units, such as geographical areas. Existing…

Methodology · Statistics 2026-05-01 Cory McCartan , Shiro Kuriwaki

Stochastic nonconvex-concave min-max saddle point problems appear in many machine learning and control problems including distributionally robust optimization, generative adversarial networks, and adversarial learning. In this paper, we…

Optimization and Control · Mathematics 2023-09-12 Morteza Boroun , Zeinab Alizadeh , Afrooz Jalilzadeh

We consider the scenario of deep clustering, in which the available prior knowledge is limited. In this scenario, few existing state-of-the-art deep clustering methods can perform well for both non-complex topology and complex topology…

Machine Learning · Statistics 2023-03-07 Yuhui Zhang , Yuichiro Wada , Hiroki Waida , Kaito Goto , Yusaku Hino , Takafumi Kanamori

This paper studies the distributed optimization problem when the objective functions might be nondifferentiable and subject to heterogeneous set constraints. Unlike existing subgradient methods, we focus on the case when the exact…

Optimization and Control · Mathematics 2021-11-23 Kui Zhu , Yutao Tang

Multi-group agnostic learning is a formal learning criterion that is concerned with the conditional risks of predictors within subgroups of a population. The criterion addresses recent practical concerns such as subgroup fairness and hidden…

Machine Learning · Computer Science 2024-06-18 Christopher Tosh , Daniel Hsu
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