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Medical imaging is frequently used in clinical practice and trials for diagnosis and treatment. Writing imaging reports is time-consuming and can be error-prone for inexperienced radiologists. Therefore, automatically generating radiology…

Computation and Language · Computer Science 2022-04-29 Zhihong Chen , Yan Song , Tsung-Hui Chang , Xiang Wan

Medicine is inherently multimodal, with rich data modalities spanning text, imaging, genomics, and more. Generalist biomedical artificial intelligence (AI) systems that flexibly encode, integrate, and interpret this data at scale can…

Building agents, systems that perceive and act upon their environment with a degree of autonomy, has long been a focus of AI research. This pursuit has recently become vastly more practical with the emergence of large language models (LLMs)…

The vast amount of biomedical information available today presents a significant challenge for investigators seeking to digest, process, and understand these findings effectively. Large Language Models (LLMs) have emerged as powerful tools…

Computation and Language · Computer Science 2024-07-19 Alexander R. Pelletier , Joseph Ramirez , Irsyad Adam , Simha Sankar , Yu Yan , Ding Wang , Dylan Steinecke , Wei Wang , Peipei Ping

Radiological imaging is central to diagnosis, treatment planning, and clinical decision-making. Vision-language foundation models have spurred interest in automated radiology report generation (RRG), but safe deployment requires reliable…

Automatic medical report generation has the potential to support clinical diagnosis, reduce the workload of radiologists, and demonstrate potential for enhancing diagnostic consistency. However, current evaluation metrics often fail to…

Computation and Language · Computer Science 2025-08-06 Zhenxuan Zhang , Kinhei Lee , Peiyuan Jing , Weihang Deng , Huichi Zhou , Zihao Jin , Jiahao Huang , Zhifan Gao , Dominic C Marshall , Yingying Fang , Guang Yang

Large language models (LLMs) often generate outdated or inaccurate information based on static training datasets. Retrieval-augmented generation (RAG) mitigates this by integrating outside data sources. While previous RAG systems used…

Large Language Models (LLMs) have significantly advanced medical question-answering by leveraging extensive clinical data and medical literature. However, the rapid evolution of medical knowledge and the labor-intensive process of manually…

Computation and Language · Computer Science 2025-07-01 Mohammad Reza Rezaei , Reza Saadati Fard , Jayson L. Parker , Rahul G. Krishnan , Milad Lankarany

Vision-Language Models (VLMs) have significantly advanced automated Radiology Report Generation (RRG). However, existing methods implicitly assume high-quality inputs, overlooking the noise and artifacts prevalent in real-world clinical…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Hongze Zhu , Chen Hu , Jiaxuan Jiang , Hong Liu , Yawen Huang , Ming Hu , Tianyu Wang , Zhijian Wu , Yefeng Zheng

Although Vision Language Models (VLMs) have shown strong generalization in medical imaging, pathology presents unique challenges due to ultra-high resolution, complex tissue structures, and nuanced clinical semantics. These factors make…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Wenchuan Zhang , Jingru Guo , Hengzhe Zhang , Penghao Zhang , Jie Chen , Shuwan Zhang , Zhang Zhang , Yuhao Yi , Hong Bu

Concept Bottleneck Models (CBMs) provide interpretable prediction by introducing an intermediate Concept Bottleneck Layer (CBL), which encodes human-understandable concepts to explain models' decision. Recent works proposed to utilize Large…

Computer Vision and Pattern Recognition · Computer Science 2025-01-17 Divyansh Srivastava , Ge Yan , Tsui-Wei Weng

Recent advances in Retrieval-Augmented Generation (RAG) have significantly improved response accuracy and relevance by incorporating external knowledge into Large Language Models (LLMs). However, existing RAG methods primarily focus on…

Machine Learning · Computer Science 2025-04-22 Qinhan Yu , Zhiyou Xiao , Binghui Li , Zhengren Wang , Chong Chen , Wentao Zhang

Radiology reports are an instrumental part of modern medicine, informing key clinical decisions such as diagnosis and treatment. The worldwide shortage of radiologists, however, restricts access to expert care and imposes heavy workloads,…

Automating radiology report generation can ease the reporting workload for radiologists. However, existing works focus mainly on the chest area due to the limited availability of public datasets for other regions. Besides, they often rely…

Computer Vision and Pattern Recognition · Computer Science 2024-10-11 Qi Chen , Yutong Xie , Biao Wu , Xiaomin Chen , James Ang , Minh-Son To , Xiaojun Chang , Qi Wu

Retrieval-augmented generation (RAG) has emerged as a promising approach to enhance the performance of large language models (LLMs) in knowledge-intensive tasks such as those from medical domain. However, the sensitive nature of the medical…

Computation and Language · Computer Science 2024-11-15 Nghia Trung Ngo , Chien Van Nguyen , Franck Dernoncourt , Thien Huu Nguyen

Radiology Report Generation (RRG) aims to produce accurate and coherent diagnostics from medical images. Although large vision language models (LVLM) improve report fluency and accuracy, they exhibit hallucinations, generating plausible yet…

Computation and Language · Computer Science 2026-02-05 Ruixiao Yang , Yuanhe Tian , Xu Yang , Huiqi Li , Yan Song

Retrieval-Augmented Generation (RAG) is widely employed to mitigate risks such as hallucinations and knowledge obsolescence in medical question answering, yet its predominantly single-round, static retrieval paradigm misaligns with the…

Computation and Language · Computer Science 2026-05-19 Yongfeng Huang , Ruiying Chen , James Cheng

Recent advances in radiology report generation (RRG) have been driven by large paired image-text datasets; however, progress in neuro-oncology has been limited due to a lack of open paired image-report datasets. Here, we introduce BTReport,…

Computer Vision and Pattern Recognition · Computer Science 2026-02-19 Juampablo E. Heras Rivera , Dickson T. Chen , Tianyi Ren , Daniel K. Low , Asma Ben Abacha , Alberto Santamaria-Pang , Mehmet Kurt

Computer-aided diagnosis systems hold great promise to aid radiologists and clinicians in radiological clinical practice and enhance diagnostic accuracy and efficiency. However, the conventional systems primarily focus on delivering…

Computer Vision and Pattern Recognition · Computer Science 2024-04-12 Sheng Wang , Tianming Du , Katherine Fischer , Gregory E Tasian , Justin Ziemba , Joanie M Garratt , Hersh Sagreiya , Yong Fan

Existing deep learning methods for radiology report generation enhance diagnostic efficiency but often overlook physician-informed medical priors. This leads to a suboptimal alignment between the structured explanations and disease…

Tissues and Organs · Quantitative Biology 2026-04-13 Aishik Konwer , Moinak Bhattacharya , Prateek Prasanna
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