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We present a new method for image reconstruction which replaces the projector in a projected gradient descent (PGD) with a convolutional neural network (CNN). CNNs trained as high-dimensional (image-to-image) regressors have recently been…

Computer Vision and Pattern Recognition · Computer Science 2018-09-11 Harshit Gupta , Kyong Hwan Jin , Ha Q. Nguyen , Michael T. McCann , Michael Unser

In a standard computed tomography (CT) image, pixels having the same Hounsfield Units (HU) can correspond to different materials and it is therefore challenging to differentiate and quantify materials. Dual-energy CT (DECT) is desirable to…

Medical Physics · Physics 2020-10-27 Wei Zhao , Tianling Lyu , Yang Chen , Lei Xing

As the medical usage of computed tomography (CT) continues to grow, the radiation dose should remain at a low level to reduce the health risks. Therefore, there is an increasing need for algorithms that can reconstruct high-quality images…

Image and Video Processing · Electrical Eng. & Systems 2021-03-10 Davood Karimi , Rabab K. Ward

Early diagnosis is essential for the successful treatment of bowel cancers including colorectal cancer (CRC) and capsule endoscopic imaging with robotic actuation can be a valuable diagnostic tool when combined with automated image…

We propose Partial Correlation Screening (PCS) as a new row-by-row approach to estimating a large precision matrix $\Omega$. To estimate the $i$-th row of $\Omega$, $1 \leq i \leq p$, PCS uses a Screen step and a Clean step. In the Screen…

Methodology · Statistics 2014-09-12 Shiqiong Huang , Jiashun Jin , Zhigang Yao

We developed a novel gamma-ray detection system (TIARA) for range monitoring in Particle Therapy. The system employs Cherenkov-based gamma-ray detection modules arranged around the target or patient, operated in time coincidence with a fast…

Spectral CT offers enhanced material discrimination over single-energy systems and enables quantitative estimation of basis material density images. Water/iodine decomposition in contrast-enhanced CT is one of the most widespread…

Medical Physics · Physics 2021-03-30 Matthew Tivnan , Grace Gang , Wenchao Cao , Nadav Shapira , Peter B. Noel , J. Webster Stayman

The analysis of multi-modality positron emission tomography and computed tomography (PET-CT) images for computer aided diagnosis applications requires combining the sensitivity of PET to detect abnormal regions with anatomical localization…

Computer Vision and Pattern Recognition · Computer Science 2019-10-29 Ashnil Kumar , Michael Fulham , Dagan Feng , Jinman Kim

We develop and validate a new algorithm called \textit{primary track recovery} (\ptr) that effectively deconvolves known physics and detector effects from nuclear recoil tracks in gas time projection chambers (TPCs) with high-resolution…

Instrumentation and Detectors · Physics 2022-04-27 P. M. Lewis , M. T. Hedges , I. Jaegle , J. Schueler , T. N. Thorpe , S. E. Vahsen

Previous deep learning efforts have focused on improving the performance of Pulmonary Embolism(PE) diagnosis from Computed Tomography (CT) scans using Convolutional Neural Networks (CNN). However, the features from CT scans alone are not…

Computer Vision and Pattern Recognition · Computer Science 2023-08-29 Santosh Sanjeev , Salwa K. Al Khatib , Mai A. Shaaban , Ibrahim Almakky , Vijay Ram Papineni , Mohammad Yaqub

Atom probe tomography (APT) is routinely used for analyzing property-enhancing particles in the nanometer-size range and below, and plays a prominent role in the analysis of solute clusters. However, the question of how well these small…

Materials Science · Physics 2020-02-25 Frédéric De Geuser , Baptiste Gault

Purpose: The FLASH effect, which reduces the radiosensitivity of healthy tissue while maintaining tumor control at high dose rates, has shown potential for improving radiation therapy. Conformal FLASH proton therapy involves advanced…

Medical Physics · Physics 2023-04-13 Sylvain Deffet , Edmond Sterpin

Hyperspectral image classification plays a pivotal role in precision agriculture, providing accurate insights into crop health monitoring, disease detection, and soil analysis. However, traditional methods struggle with high-dimensional…

Computer Vision and Pattern Recognition · Computer Science 2025-07-15 Fuyin Ye , Erwen Yao , Jianyong Chen , Fengmei He , Junxiang Zhang , Lihao Ni

Dose reduction in computed tomography (CT) is essential for decreasing radiation risk in clinical applications. Iterative reconstruction is one of the most promising ways to compensate for the increased noise due to reduction of photon…

Image and Video Processing · Electrical Eng. & Systems 2021-03-24 Zhuonan He , Yikun Zhang , Yu Guan , Shanzhou Niu , Yi Zhang , Yang Chen , Qiegen Liu

Cone beam computed tomography (CBCT)-guided puncture has become an established approach for diagnosing and treating early- to mid-stage thoracic tumours, yet the associated radiation exposure substantially elevates the risk of secondary…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Haoshen Wang , Lei Chen , Wei-Hua Zhang , Linxia Wu , Yong Luo , Zengmao Wang , Yuan Xiong , Chengcheng Zhu , Wenjuan Tang , Xueyi Zhang , Wei Zhou , Xuhua Duan , Lefei Zhang , Gao-Jun Teng , Bo Du , Huangxuan Zhao

Weight pruning is a powerful technique to realize model compression. We propose PCNN, a fine-grained regular 1D pruning method. A novel index format called Sparsity Pattern Mask (SPM) is presented to encode the sparsity in PCNN. Leveraging…

Machine Learning · Computer Science 2020-06-16 Zhanhong Tan , Jiebo Song , Xiaolong Ma , Sia-Huat Tan , Hongyang Chen , Yuanqing Miao , Yifu Wu , Shaokai Ye , Yanzhi Wang , Dehui Li , Kaisheng Ma

Nuclei classification is a critical step in computer-aided diagnosis with histopathology images. In the past, various methods have employed graph neural networks (GNN) to analyze cell graphs that model inter-cell relationships by…

Computer Vision and Pattern Recognition · Computer Science 2024-02-21 Wei Lou , Guanbin Li , Xiang Wan , Haofeng Li

We customize an end-to-end image compression framework for retina OCT images based on deep convolutional neural networks (CNNs). The customized compression scheme consists of three parts: data Preprocessing, compression CNNs, and…

Image and Video Processing · Electrical Eng. & Systems 2019-08-28 Pengfei Guo , Dawei Li , Xingde Li

Current computational methods for exon-intron structure prediction from a cluster of transcript (EST, mRNA) data do not exhibit the time and space efficiency necessary to process large clusters of over than 20,000 ESTs and genes longer than…

Genomics · Quantitative Biology 2010-05-11 Paola Bonizzoni , Gianluca Della Vedova , Yuri Pirola , Raffaella Rizzi

The TOP-IMPLART project consists of the design and implementation of a linear proton accelerator, its control and monitoring systems for the treatment of superficial and semi-deep tumors. The energy of 150 MeV (corresponding to a…