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Purpose: The importance of robust proton treatment planning to mitigate the impact of uncertainty is well understood. However, its computational cost grows with the number of uncertainty scenarios, prolonging the treatment planning process.…

Medical Physics · Physics 2023-05-01 Anqi Fu , Vicki T. Taasti , Masoud Zarepisheh

Transformers are very powerful tools for a variety of tasks across domains, from text generation to image captioning. However, transformers require substantial amounts of training data, which is often a challenge in biomedical settings,…

Computer Vision and Pattern Recognition · Computer Science 2023-07-04 Andrew Kean Gao

Radiotherapy is a primary treatment for cancers with the aim of applying sufficient radiation dose to the planning target volume (PTV) while minimizing dose hazards to the organs at risk (OARs). Convolutional neural networks (CNNs) have…

Image and Video Processing · Electrical Eng. & Systems 2024-02-08 Lu Wen , Qihun Zhang , Zhenghao Feng , Yuanyuan Xu , Xiao Chen , Jiliu Zhou , Yan Wang

Background: Upright proton therapy with compact delivery systems has the potential to reduce costs for treatments but could also lead to broadening of the beam penumbra due to energy selection close to the patient. Purpose: This study aims…

Medical Physics · Physics 2025-08-22 Erik Engwall , Victor Mikhalev , Johan Sundström , Otte Marthin , Viktor Wase

Objective: To develop and validate an independent Monet Carlo dose calculation engine to support for software verification of treatment planning systems and quality assurance workflow. Method: GATE Monte Carlo toolkit was employed to…

Medical Physics · Physics 2021-07-27 A. Asadi , A. Akhavanallaf , S. A. Hosseini , N. vosoughi , H. Zaidi

In this work, we present a fundamental mathematical model for proton transport, tailored to capture the key physical processes underpinning Proton Beam Therapy (PBT). The model provides a robust and computationally efficient framework for…

Purpose: Intensity-modulated proton therapy (IMPT) offers precise tumor coverage while sparing organs at risk (OARs) in head and neck (H&N) cancer. However, its sensitivity to anatomical changes requires frequent adaptation through online…

Riptide is a detector concept aiming to track fast neutrons. It is based on neutron--proton elastic collisions inside a plastic scintillator, where the neutron momentum can be measured by imaging the scintillation light. More specifically,…

Correcting scan-positional errors is critical in achieving electron ptychography with both high resolution and high precision. This is a demanding and challenging task due to the sheer number of parameters that need to be optimized. For…

Other Condensed Matter · Physics 2022-11-08 Shoucong Ning , Wenhui Xu , Leyi Loh , Zhen Lu , Michel Bosman , Fucai Zhang , Qian He

The Most Likely Path formalism (MLP) is widely established as the most statistically precise method for proton path reconstruction in proton computed tomography (pCT). However, while this method accounts for small-angle Multiple Coulomb…

Medical Physics · Physics 2021-05-26 T. Ackernley , G. Casse , M. Cristoforetti

Photon-Counting Computed Tomography (PCCT) is a novel imaging modality that simultaneously acquires volumetric data at multiple X-ray energy levels, generating separate volumes that capture energy-dependent attenuation properties.…

Human-Computer Interaction · Computer Science 2025-08-21 Mohit Sharma , Emma Nilsson , Martin Falk , Talha Bin Masood , Lee Jollans , Anders Persson , Tino Ebbers , Ingrid Hotz

Proton therapy provides superior dose conformity compared with photon radiotherapy, concentrating radiation within the tumor while sparing adjacent healthy tissue. This advantage has been most effectively realized for static tumors in…

Medical Physics · Physics 2025-10-09 Vivek Maradia , Nick Yue , Adam Molzahn , Jingqian Wang , Mark Pankuch , Serdar Charyyev , Billy W. Loo

Detailed pulmonary airway segmentation is a clinically important task for endobronchial intervention and treatment of peripheral located lung cancer lesions. Convolutional Neural Networks (CNNs) are promising tools for medical image…

Computer Vision and Pattern Recognition · Computer Science 2023-11-15 Minghui Zhang , Guang-Zhong Yang , Yun Gu

Transformer-based 3D human pose estimation methods suffer from high computational costs due to the quadratic complexity of self-attention with respect to sequence length. Additionally, pose sequences often contain significant redundancy…

Computer Vision and Pattern Recognition · Computer Science 2025-10-10 Zenghao Zheng , Lianping Yang , Hegui Zhu , Mingrui Ye

Parameter-efficient transfer learning (PETL) is proposed as a cost-effective way to transfer pre-trained models to downstream tasks, avoiding the high cost of updating entire large-scale pre-trained models (LPMs). In this work, we present…

Computer Vision and Pattern Recognition · Computer Science 2024-07-03 Yijin Huang , Pujin Cheng , Roger Tam , Xiaoying Tang

Whole-body PET/CT scan is an important tool for diagnosing various malignancies (e.g., malignant melanoma, lymphoma, or lung cancer), and accurate segmentation of tumors is a key part for subsequent treatment. In recent years, CNN-based…

Image and Video Processing · Electrical Eng. & Systems 2023-02-27 Hengzhi Xue , Qingqing Fang , Yudong Yao , Yueyang Teng

The detection of nuclei and cells in histology images is of great value in both clinical practice and pathological studies. However, multiple reasons such as morphological variations of nuclei or cells make it a challenging task where…

Computer Vision and Pattern Recognition · Computer Science 2021-06-28 Yibao Sun , Xingru Huang , Huiyu Zhou , Qianni Zhang

Point cloud recognition is an essential task in industrial robotics and autonomous driving. Recently, several point cloud processing models have achieved state-of-the-art performances. However, these methods lack rotation robustness, and…

Computer Vision and Pattern Recognition · Computer Science 2021-12-30 Dongrui Liu , Chuanchuan Chen , Changqing Xu , Qi Cai , Lei Chu , Fei Wen , Robert Caiming Qiu

Intensity-modulated proton therapy (IMPT) employs proton radiation rather than conventional X-rays to treat cancerous tumors. This approach offers significant advantages by minimizing the radiation exposure of surrounding healthy tissue,…

In this paper, we present a novel approach to detect ground control points (GCPs) for stereo matching problem. First of all, we train a convolutional neural network (CNN) on a large stereo set, and compute the matching confidence of each…

Computer Vision and Pattern Recognition · Computer Science 2016-05-10 Zhun Zhong , Songzhi Su , Donglin Cao , Shaozi Li
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