Related papers: Advanced biomarker analysis for early Alzheimer's …

The receiver operating characteristic (ROC) curve is an important graphic tool for evaluating a test in a wide range of disciplines. While useful, an ROC curve can cross the chance line, either by having an S-shape or a hook at the extreme…

In diagnostic studies, researchers frequently encounter imperfect reference standards with some misclassified labels. Treating these as gold standards can bias receiver operating characteristic (ROC) curve analysis. To address this issue,…

Accurately discriminating progressive stages of Alzheimer's Disease (AD) is crucial for early diagnosis and prevention. It often involves multiple imaging modalities to understand the complex pathology of AD, however, acquiring a complete…

The area under the ROC curve (AUC) is the standard measure of a biomarker's discriminatory accuracy; however, naive AUC estimates can be misleading when validation cohorts differ from the intended target population. Such covariate shifts…

Retinal optical coherence tomography (OCT) images are the biomarkers for neurodegenerative diseases, which are rising in prevalence. Early detection of Alzheimer's disease using retinal OCT is a primary challenging task. This work utilizes…

The Receiver Operating Characteristic (ROC) surface is a generalization of ROC curve and is widely used for assessment of the accuracy of diagnostic tests on three categories. A complication called the verification bias, meaning that not…

Introduction- This paper mainly describes a way to detect with high accuracy patients with early-stage Alzheimer's disease (ES-AD) versus healthy control (HC) subjects, from datasets built with handwriting and drawing task records. Method-…

The current methods for diagnosing Alzheimer Disease using Magnetic Resonance Imaging (MRI) have significant limitations. Many previous studies used 2D Transformers to analyze individual brain slices independently, potentially losing…

Alterations in retinal layer thickness, measurable using Optical Coherence Tomography (OCT), have been associated with neurodegenerative diseases such as Alzheimer's disease (AD). While previous studies have mainly focused on segmented…

Alzheimer's is a brain disease that gets worse over time and affects memory, thinking, and behavior. Alzheimer's disease (AD) can be treated and managed if it is diagnosed early, which can slow the progression of symptoms and improve…

Ordinal learning (OL) is a type of machine learning models with broad utility in health care applications such as diagnosis of different grades of a disease (e.g., mild, modest, severe) and prediction of the speed of disease progression…

Object detection (OD) in computer vision has made significant progress in recent years, transitioning from closed-set labels to open-vocabulary detection (OVD) based on large-scale vision-language pre-training (VLP). However, current…

When sufficient labeled data are available, classical criteria based on Receiver Operating Characteristic (ROC) or Precision-Recall (PR) curves can be used to compare the performance of un-supervised anomaly detection algorithms. However ,…

Receiver operating characteristic (ROC) curve is an informative tool in binary classification and Area Under ROC Curve (AUC) is a popular metric for reporting performance of binary classifiers. In this paper, first we present a…

Early detection of Alzheimer's disease's precursor stages is imperative for significantly enhancing patient outcomes and quality of life. This challenge is tackled through a semi-supervised multi-modal diagnosis framework. In particular, we…

While the area under the ROC curve is perhaps the most common measure that is used to rank the relative performance of different binary classifiers, longstanding field folklore has noted that it can be a measure that ill-captures the…

The ROC-SVM, originally proposed by Rakotomamonjy, directly maximizes the area under the ROC curve (AUC) and has become an attractive alternative of the conventional binary classification under the presence of class imbalance. However, its…

To assess the classification accuracy of a continuous diagnostic result, the receiver operating characteristic (ROC) curve is commonly used in applications. The partial area under the ROC curve (pAUC) is one of widely accepted summary…

Throughout science and technology, receiver operating characteristic (ROC) curves and associated area under the curve (AUC) measures constitute powerful tools for assessing the predictive abilities of features, markers and tests in binary…

Confirming Alzheimer's disease (AD) typically relies on positron emission tomography (PET), which remains costly and invasive, motivating the use of structural MRI-based prescreening. Deep learning on non-Euclidean manifolds, particularly…