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The adoption of large language models (LLMs) to assist clinicians has attracted remarkable attention. Existing works mainly adopt the close-ended question-answering (QA) task with answer options for evaluation. However, many clinical…

Multimodal language modeling has enabled breakthroughs for representation learning, yet remains unexplored in the realm of functional brain data for clinical phenotyping. This paper pioneers EEG-language models (ELMs) trained on clinical…

Signal Processing · Electrical Eng. & Systems 2025-08-12 Sam Gijsen , Kerstin Ritter

Electronic Health Record (EHR) provides abundant information through various modalities. However, learning multi-modal EHR is currently facing two major challenges, namely, 1) data embedding and 2) cases with missing modality. A lack of…

Machine Learning · Computer Science 2023-05-05 Kwanhyung Lee , Soojeong Lee , Sangchul Hahn , Heejung Hyun , Edward Choi , Byungeun Ahn , Joohyung Lee

Background: Large language models (LLMs) show promise in medicine, but their deployment in hospitals is limited by restricted access to electronic health record (EHR) systems. The Model Context Protocol (MCP) enables integration between…

Artificial Intelligence · Computer Science 2025-09-22 Kanato Masayoshi , Masahiro Hashimoto , Ryoichi Yokoyama , Naoki Toda , Yoshifumi Uwamino , Shogo Fukuda , Ho Namkoong , Masahiro Jinzaki

Users typically engage with LLMs interactively, yet most existing benchmarks evaluate them in a static, single-turn format, posing reliability concerns in interactive scenarios. We identify a key obstacle towards reliability: LLMs are…

Computation and Language · Computer Science 2024-11-08 Shuyue Stella Li , Vidhisha Balachandran , Shangbin Feng , Jonathan S. Ilgen , Emma Pierson , Pang Wei Koh , Yulia Tsvetkov

Europe's healthcare systems require enhanced interoperability and digitalization, driving a demand for innovative solutions to process legacy clinical data. This paper presents the results of our project, which aims to leverage Large…

Computation and Language · Computer Science 2025-07-09 Aynur Guluzade , Naguib Heiba , Zeyd Boukhers , Florim Hamiti , Jahid Hasan Polash , Yehya Mohamad , Carlos A Velasco

Disease diagnosis is a central pillar of modern healthcare, enabling early detection and timely intervention for acute conditions while guiding lifestyle adjustments and medication regimens to prevent or slow chronic disease. Self-reports…

Computation and Language · Computer Science 2025-11-10 Yuexin Wu , Shiqi Wang , Vasile Rus

Language models (LMs) represent an emerging paradigm within artificial intelligence, with applications throughout the medical enterprise. A comprehensive understanding of the clinical task and awareness of the variability in performance…

Machine Learning · Computer Science 2026-03-09 Victor Garcia , Mariia Sidulova , Aldo Badano

Accurate prediction of clinical outcomes using Electronic Health Records (EHRs) is critical for early intervention, efficient resource allocation, and improved patient care. EHRs contain multimodal data, including both structured data and…

Machine Learning · Computer Science 2025-08-29 Rituparna Datta , Jiaming Cui , Zihan Guan , Vishal G. Reddy , Joshua C. Eby , Gregory Madden , Rupesh Silwal , Anil Vullikanti

The use of machine learning in Healthcare has the potential to improve patient outcomes as well as broaden the reach and affordability of Healthcare. The history of other application areas indicates that strong benchmarks are essential for…

The precipitous rise and adoption of Large Language Models (LLMs) have shattered expectations with the fastest adoption rate of any consumer-facing technology in history. Healthcare, a field that traditionally uses NLP techniques, was bound…

Computation and Language · Computer Science 2023-10-10 Surjya Ray , Pratik Mehta , Hongen Zhang , Ada Chaman , Jian Wang , Chung-Jen Ho , Michael Chiou , Tashfeen Suleman

Clinical reasoning agents based on large language models (LLMs) aim to automate tasks such as intensive care unit (ICU) monitoring and patient state tracking from electronic health records (EHRs). Existing systems typically rely on manually…

Artificial Intelligence · Computer Science 2026-05-12 Timothy Ossowski , Xinchi Liu , Danyal Maqbool , Vaibhav Dhanuka , Sheng Zhang , Hoifung Poon , Majid Afshar , Tyler Bradshaw , Junjie Hu

Electronic health records (EHR's) are only a first step in capturing and utilizing health-related data - the problem is turning that data into useful information. Models produced via data mining and predictive analysis profile inherited…

Databases · Computer Science 2011-12-08 Casey Bennett , Thomas Doub

Medical Large language models achieve strong scores on standard benchmarks; however, the transfer of those results to safe and reliable performance in clinical workflows remains a challenge. This survey reframes evaluation through a…

Transformers have significantly advanced the modeling of Electronic Health Records (EHR), yet their deployment in real-world healthcare is limited by several key challenges. Firstly, the quadratic computational cost and insufficient context…

Machine Learning · Computer Science 2024-11-18 Adibvafa Fallahpour , Mahshid Alinoori , Wenqian Ye , Xu Cao , Arash Afkanpour , Amrit Krishnan

Generative Artificial Intelligence is set to revolutionize healthcare delivery by transforming traditional patient care into a more personalized, efficient, and proactive process. Chatbots, serving as interactive conversational models, will…

Automated clinical text anonymization has the potential to unlock the widespread sharing of textual health data for secondary usage while assuring patient privacy and safety. Despite the proposal of many complex and theoretically successful…

Computation and Language · Computer Science 2024-06-05 David Pissarra , Isabel Curioso , João Alveira , Duarte Pereira , Bruno Ribeiro , Tomás Souper , Vasco Gomes , André V. Carreiro , Vitor Rolla

Electronic Health Records (EHRs) and routine documentation practices play a vital role in patients' daily care, providing a holistic record of health, diagnoses, and treatment. However, complex and verbose EHR narratives overload healthcare…

Computation and Language · Computer Science 2025-02-26 Yanjun Gao , Ruizhe Li , Emma Croxford , John Caskey , Brian W Patterson , Matthew Churpek , Timothy Miller , Dmitriy Dligach , Majid Afshar

Medical consultation dialogues contain critical clinical information, yet their unstructured nature hinders effective utilization in diagnosis and treatment. Traditional methods, relying on rule-based or shallow machine learning techniques,…

Computation and Language · Computer Science 2025-04-24 Shuguang Zhao , Qiangzhong Feng , Zhiyang He , Peipei Sun , Yingying Wang , Xiaodong Tao , Xiaoliang Lu , Mei Cheng , Xinyue Wu , Yanyan Wang , Wei Liang

Clinical notes in Electronic Health Records (EHR) present rich documented information of patients to inference phenotype for disease diagnosis and study patient characteristics for cohort selection. Unsupervised user embedding aims to…

Computation and Language · Computer Science 2022-03-30 Xiaolei Huang , Franck Dernoncourt , Mark Dredze