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Single-cell analysis is currently one of the most high-resolution techniques to study biology. The large complex datasets that have been generated have spurred numerous developments in computational biology, in particular the use of…

Genomics · Quantitative Biology 2023-04-27 Ionut Sebastian Mihai , Sarang Chafle , Johan Henriksson

Data is becoming more complex, and so are the approaches designed to process it. Enterprises have access to more data than ever, but many still struggle to glean the full potential of insights from what they have. This research explores the…

Software Engineering · Computer Science 2024-02-20 Mohammad Heydari , Zahra Rezvani

Leveraging machine-learning (ML) techniques for compiler optimizations has been widely studied and explored in academia. However, the adoption of ML in general-purpose, industry strength compilers has yet to happen. We propose MLGO, a…

Programming Languages · Computer Science 2021-01-14 Mircea Trofin , Yundi Qian , Eugene Brevdo , Zinan Lin , Krzysztof Choromanski , David Li

Continual learning (CL) aims to empower machine learning models to learn continually from new data, while building upon previously acquired knowledge without forgetting. As models have evolved from small to large pre-trained architectures,…

Machine Learning · Computer Science 2026-03-31 Dianzhi Yu , Xinni Zhang , Yankai Chen , Aiwei Liu , Yifei Zhang , Philip S. Yu , Irwin King

This paper introduces the Modular Neural Computer (MNC), a memory-augmented neural architecture for exact algorithmic computation on variable-length inputs. The model combines an external associative memory of scalar cells, explicit read…

Machine Learning · Computer Science 2026-03-17 Florin Leon

Modern methods often formulate the counting of cells from microscopic images as a regression problem and more or less rely on expensive, manually annotated training images (e.g., dot annotations indicating the centroids of cells or…

Image and Video Processing · Electrical Eng. & Systems 2021-05-18 Xin Ding , Qiong Zhang , William J. Welch

Machine learning potentials (MLPs) trained on accurate quantum chemical data can retain the high accuracy, while inflicting little computational demands. On the downside, they need to be trained for each individual system. In recent years,…

Machine Learning · Computer Science 2023-09-13 Marco Eckhoff , Markus Reiher

As modern scientific instruments generate vast amounts of data and the volume of information in the scientific literature continues to grow, machine learning (ML) has become an essential tool for organising, analysing, and interpreting…

High-throughput technologies such as next generation sequencing allow biologists to observe cell function with unprecedented resolution, but the resulting datasets are too large and complicated for humans to understand without the aid of…

Applications · Statistics 2021-10-08 David S. Watson

Machine learning (ML) empowers biomedical systems with the capability to optimize their performance through modeling of the available data extremely well, without using strong assumptions about the modeled system. Especially in nano-scale…

Backgrounds: Artificial intelligence (AI) is transforming healthcare, yet translating AI models from theoretical frameworks to real-world clinical applications remains challenging. The Mayo Clinic Platform (MCP) was established to address…

Machine Learning (ML) models are trained using historical data to classify new, unseen data. However, traditional computing resources often struggle to handle the immense amount of data, commonly known as Big Data, within a reasonable time…

Quantum Physics · Physics 2024-11-01 Minati Rath , Hema Date

Recent developments in machine learning interatomic potentials (MLIPs) have empowered even non-experts in machine learning to train MLIPs for accelerating materials simulations. However, the current literature lacks clear standards for…

Chemical Physics · Physics 2024-01-05 Tristan Maxson , Ademola Soyemi , Benjamin W. J. Chen , Tibor Szilvási

The adoption of machine learning (ML) and deep learning methods has revolutionized molecular medicine by driving breakthroughs in genomics, transcriptomics, drug discovery, and biological systems modeling. The increasing quantity,…

Solving Constraint Optimization Problems (COPs) can be dramatically simplified by boundary estimation, that is, providing tight boundaries of cost functions. By feeding a supervised Machine Learning (ML) model with data composed of known…

Artificial Intelligence · Computer Science 2021-11-08 Helge Spieker , Arnaud Gotlieb

In the rapidly evolving research on artificial intelligence (AI) the demand for fast, computationally efficient, and scalable solutions has increased in recent years. The problem of optimizing the computing resources for distributed machine…

Machine Learning · Computer Science 2025-10-30 Mohammadreza Doostmohammadian , Zulfiya R. Gabidullina , Hamid R. Rabiee

Machine learning (ML) has emerged as a pervasive tool in science, engineering, and beyond. Its success has also led to several synergies with molecular dynamics (MD) simulations, which we use to identify and characterize the major…

Biomolecules · Quantitative Biology 2022-05-09 Christopher Kolloff , Simon Olsson

Detecting arousals in sleep is essential for diagnosing sleep disorders. However, using Machine Learning (ML) in clinical practice is impeded by fundamental issues, primarily due to mismatches between clinical protocols and ML methods.…

Machine Learning · Computer Science 2024-09-23 Stefan Kraft , Andreas Theissler , Vera Wienhausen-Wilke , Philipp Walter , Gjergji Kasneci

When dealing with real-world optimization problems, decision-makers usually face high levels of uncertainty associated with partial information, unknown parameters, or complex relationships between these and the problem decision variables.…

Optimization and Control · Mathematics 2023-05-01 Antonio Alcántara , Carlos Ruiz

In recent advancements, multimodal large language models (MLLMs) have been fine-tuned on specific medical image datasets to address medical visual question answering (Med-VQA) tasks. However, this common approach of task-specific…

Computer Vision and Pattern Recognition · Computer Science 2024-10-08 Lai Wei , Wenkai Wang , Xiaoyu Shen , Yu Xie , Zhihao Fan , Xiaojin Zhang , Zhongyu Wei , Wei Chen
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