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Traditional Chinese Medicine (TCM) formulas play a significant role in treating epidemics and complex diseases. Existing models for TCM utilize traditional algorithms or deep learning techniques to analyze formula relationships, yet lack…

Computation and Language · Computer Science 2025-09-09 ZiXuan Zhang , Bowen Hao , Yingjie Li , Hongzhi Yin

Traditional Chinese Medicine (TCM) involves complex compatibility mechanisms characterized by multi-component and multi-target interactions, which are challenging to quantify. To address this challenge, we applied graph artificial…

Machine Learning · Computer Science 2024-12-11 Jingqi Zeng , Xiaobin Jia

Background: Retrieval augmented generation (RAG) technology can empower large language models (LLMs) to generate more accurate, professional, and timely responses without fine tuning. However, due to the complex reasoning processes and…

Computation and Language · Computer Science 2026-02-27 Jianmin Li , Ying Chang , Su-Kit Tang , Yujia Liu , Yanwen Wang , Shuyuan Lin , Binkai Ou

Traditional Chinese Medicine (TCM), with a history spanning over two millennia, plays a role in global healthcare. However, applying large language models (LLMs) to TCM remains challenging due to its reliance on holistic reasoning, implicit…

Computation and Language · Computer Science 2025-10-21 Jiacheng Xie , Yang Yu , Yibo Chen , Hanyao Zhang , Lening Zhao , Jiaxuan He , Lei Jiang , Xiaoting Tang , Guanghui An , Dong Xu

Traditional Chinese Medicine (TCM) is a holistic medical system with millennia of accumulated clinical experience, playing a vital role in global healthcare-particularly across East Asia. However, the implicit reasoning, diverse textual…

Computation and Language · Computer Science 2025-06-03 Shufeng Kong , Xingru Yang , Yuanyuan Wei , Zijie Wang , Hao Tang , Jiuqi Qin , Shuting Lan , Yingheng Wang , Junwen Bai , Zhuangbin Chen , Zibin Zheng , Caihua Liu , Hao Liang

Natural medicines, particularly Traditional Chinese Medicine (TCM), are gaining global recognition for their therapeutic potential in addressing human symptoms and diseases. TCM, with its systematic theories and extensive practical…

Computation and Language · Computer Science 2025-05-20 Zhi Liu , Tao Yang , Jing Wang , Yexin Chen , Zhan Gao , Jiaxi Yang , Kui Chen , Bingji Lu , Xiaochen Li , Changyong Luo , Yan Li , Xiaohong Gu , Peng Cao

This paper details a technical plan for building a clinical case database for Traditional Chinese Medicine (TCM) using web scraping. Leveraging multiple platforms, including 360doc, we gathered over 5,000 TCM clinical cases, performed data…

Computation and Language · Computer Science 2024-11-26 Peng Xu , Hongjin Wu , Jinle Wang , Rongjia Lin , Liwei Tan

Large Language Models (LLMs) have demonstrated remarkable capabilities in modern medicine, yet their application in Traditional Chinese Medicine (TCM) remains severely limited by the absence of standardized benchmarks and the scarcity of…

Computation and Language · Computer Science 2025-12-29 Zihao Cheng , Yuheng Lu , Huaiqian Ye , Zeming Liu , Minqi Wang , Jingjing Liu , Zihan Li , Wei Fan , Yuanfang Guo , Ruiji Fu , Shifeng She , Gang Wang , Yunhong Wang

The recently unprecedented advancements in Large Language Models (LLMs) have propelled the medical community by establishing advanced medical-domain models. However, due to the limited collection of medical datasets, there are only a few…

Computation and Language · Computer Science 2024-06-10 Ping Yu , Kaitao Song , Fengchen He , Ming Chen , Jianfeng Lu

The surge of large language models (LLMs) has driven significant progress in medical applications, including traditional Chinese medicine (TCM). However, current medical LLMs struggle with TCM diagnosis and syndrome differentiation due to…

Computation and Language · Computer Science 2025-10-01 Sibo Wei , Xueping Peng , Yi-Fei Wang , Tao Shen , Jiasheng Si , Weiyu Zhang , Fa Zhu , Athanasios V. Vasilakos , Wenpeng Lu , Xiaoming Wu , Yinglong Wang

Large language models (LLMs) have demonstrated exceptional capabilities in general domains, yet their application in highly specialized and culturally-rich fields like Traditional Chinese Medicine (TCM) requires rigorous and nuanced…

Computation and Language · Computer Science 2025-11-18 Tianai Huang , Jiayuan Chen , Lu Lu , Pengcheng Chen , Tianbin Li , Bing Han , Wenchao Tang , Jie Xu , Ming Li

Traditional Chinese Medicine (TCM), as an effective alternative medicine, has been receiving increasing attention. In recent years, the rapid development of large language models (LLMs) tailored for TCM has highlighted the urgent need for…

Computation and Language · Computer Science 2025-10-28 Jiacheng Xie , Yang Yu , Ziyang Zhang , Shuai Zeng , Jiaxuan He , Ayush Vasireddy , Xiaoting Tang , Congyu Guo , Lening Zhao , Congcong Jing , Guanghui An , Dong Xu

Traditional Chinese Medicine (TCM) has seen increasing adoption in healthcare, with specialized Large Language Models (LLMs) emerging to support clinical applications. A fundamental requirement for these models is accurate identification of…

Computation and Language · Computer Science 2025-04-16 Sifan Li , Yujun Cai , Bryan Hooi , Nanyun Peng , Yiwei Wang

Large language models (LLMs) have performed remarkably well in various natural language processing tasks by benchmarking, including in the Western medical domain. However, the professional evaluation benchmarks for LLMs have yet to be…

Computation and Language · Computer Science 2024-06-04 Wenjing Yue , Xiaoling Wang , Wei Zhu , Ming Guan , Huanran Zheng , Pengfei Wang , Changzhi Sun , Xin Ma

Despite the success of large language models (LLMs) in various domains, their potential in Traditional Chinese Medicine (TCM) remains largely underexplored due to two critical barriers: (1) the scarcity of high-quality TCM data and (2) the…

Computation and Language · Computer Science 2025-08-21 Junying Chen , Zhenyang Cai , Zhiheng Liu , Yunjin Yang , Rongsheng Wang , Qingying Xiao , Xiangyi Feng , Zhan Su , Jing Guo , Xiang Wan , Guangjun Yu , Haizhou Li , Benyou Wang

Metaphorical expressions are abundant in Traditional Chinese Medicine (TCM), conveying complex disease mechanisms and holistic health concepts through culturally rich and often abstract terminology. Bridging these metaphors to anatomically…

Computation and Language · Computer Science 2025-03-05 Jiacheng Tang , Nankai Wu , Fan Gao , Chengxiao Dai , Mengyao Zhao , Xinjie Zhao

Large language models (LLMs) excel in various NLP tasks and modern medicine, but their evaluation in traditional Chinese medicine (TCM) is underexplored. To address this, we introduce TCM3CEval, a benchmark assessing LLMs in TCM across…

Computation and Language · Computer Science 2025-03-11 Tianai Huang , Lu Lu , Jiayuan Chen , Lihao Liu , Junjun He , Yuping Zhao , Wenchao Tang , Jie Xu

Traditional Chinese medicine (TCM) has relied on specific combinations of herbs in prescriptions to treat various symptoms and signs for thousands of years. Predicting TCM prescriptions poses a fascinating technical challenge with…

Computation and Language · Computer Science 2024-12-13 Xingzhi Zhou , Xin Dong , Chunhao Li , Yuning Bai , Yulong Xu , Ka Chun Cheung , Simon See , Xinpeng Song , Runshun Zhang , Xuezhong Zhou , Nevin L. Zhang

Traditional Chinese Medicine diagnosis and treatment principles, established through centuries of trial-and-error clinical practice, directly maps patient-specific symptom patterns to personalised herbal therapies. These empirical holistic…

Traditional Chinese Medicine (TCM) is a natural, safe, and effective therapy that has spread and been applied worldwide. The unique TCM diagnosis and treatment system requires a comprehensive analysis of a patient's symptoms hidden in the…

Computation and Language · Computer Science 2022-08-04 Mucheng Ren , Heyan Huang , Yuxiang Zhou , Qianwen Cao , Yuan Bu , Yang Gao
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