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Advances in imagery at atomic and near-atomic resolution, such as cryogenic electron microscopy (cryo-EM), have led to an influx of high resolution images of proteins and other macromolecular structures to data banks worldwide. Producing a…

Quantitative Methods · Quantitative Biology 2021-04-06 Nathan Ranno , Dong Si

The complex dynamics of the heart are reflected in its electrical activity, captured through electrocardiograms (ECGs). In this study we use nonlinear time series analysis to understand how ECG complexity varies with cardiac pathology.…

Signal Processing · Electrical Eng. & Systems 2025-10-22 Camilo Quiceno Quintero , Sandip Varkey George

We have compiled a set of electron-impact multiple ionization (EIMI) cross sections for astrophysically relevant ions. EIMI can have a significant effect on the ionization balance of non-equilibrium plasmas. For example, it can be important…

Instrumentation and Methods for Astrophysics · Physics 2017-12-06 Michael Hahn , Alfred Mueller , Daniel Wolf Savin

Boundary element methods (BEM) are used for forward computation of bioelectromagnetic fields in multi-compartment volume conductor models. Most BEM approaches assume that each compartment is in contact with at most one external compartment.…

Classical Physics · Physics 2016-11-24 Matti Stenroos

We review some of the latest approaches to analysing cardiac electrophysiology data using machine learning and predictive modelling. Cardiac arrhythmias, particularly atrial fibrillation, are a major global healthcare challenge. Treatment…

The finite cell method (FCM) belongs to the class of immersed boundary methods, and combines the fictitious domain approach with high-order approximation, adaptive integration and weak imposition of unfitted Dirichlet boundary conditions.…

Numerical Analysis · Mathematics 2018-07-04 Dominik Schillinger , Quanji Cai , Ralf-Peter Mundani , Ernst Rank

This article reviews the mechanical bidomain model, a mathematical description how the extracellular matrix and intracellular cytoskeleton are coupled by integrin proteins. The fundamental hypothesis is that differences between…

Biological Physics · Physics 2016-11-28 Bradley J. Roth

The Expectation--Maximization (EM) algorithm is a simple meta-algorithm that has been used for many years as a methodology for statistical inference when there are missing measurements in the observed data or when the data is composed of…

Machine Learning · Statistics 2022-11-15 Hideitsu Hino , Shotaro Akaho , Noboru Murata

Finite element methods have been shown to achieve high accuracies in numerically solving the EEG forward problem and they enable the realistic modeling of complex geometries and important conductive features such as anisotropic…

Numerical Analysis · Mathematics 2017-08-25 Johannes Vorwerk , Christian Engwer , Sampsa Pursiainen , Carsten H. Wolters

The Cardioid distribution is a relevant model for circular data. However, this model is not suitable for scenarios were there is asymmetry or multimodality. In order to overcome this gap, an extended Cardioid model is proposed, which is…

Methodology · Statistics 2017-12-06 Fernanda V. Paula , Abraão D. C. Nascimento , Getúlio J. A. Amaral

We present a 2.5-dimensional charge-conservative electromagnetic particle-in-cell (EM-PIC) algorithm optimized for the analysis of vacuum electronic devices (VED) with cylindrical symmetry (axisymmetry). We explore the axisymmetry present…

Solving the electroencephalography (EEG) forward problem is a fundamental step in a wide range of applications including biomedical imaging techniques based on inverse source localization. State-of-the-art electromagnetic solvers resort to…

Computational Physics · Physics 2020-04-22 Maxime Y. Monin , Lyes Rahmouni , Adrien Merlini , Francesco P. Andriulli

Recent advances have increasingly applied large language models (LLMs) to electrocardiogram (ECG) interpretation, giving rise to Electrocardiogram-Language Models (ELMs). Conditioned on an ECG and a textual query, an ELM autoregressively…

Artificial Intelligence · Computer Science 2025-05-27 William Han , Chaojing Duan , Zhepeng Cen , Yihang Yao , Xiaoyu Song , Atharva Mhaskar , Dylan Leong , Michael A. Rosenberg , Emerson Liu , Ding Zhao

Heart failure is one of the most common causes of death in the western world. Many heart problems are linked to disturbances in cardiac electrical activity, such as wave re-entry caused by ischaemia. In terms of mathematical modelling, the…

Numerical Analysis · Mathematics 2018-09-24 Megan E. Farquhar , Timothy J. Moroney , Qianqian Yang , Ian W. Turner , Kevin Burrage

Cardiac arrhythmia, a condition characterized by irregular heartbeats, often serves as an early indication of various heart ailments. With the advent of deep learning, numerous innovative models have been introduced for diagnosing…

Machine Learning · Computer Science 2024-07-31 Yinlong Xu , Xiaoqiang Liu , Zitai Kong , Yixuan Wu , Yue Wang , Yingzhou Lu , Honghao Gao , Jian Wu , Hongxia Xu

Electroencephalography (EEG) analysis stands at the forefront of neuroscience and artificial intelligence research, where foundation models are reshaping the traditional EEG analysis paradigm by leveraging their powerful representational…

Human-Computer Interaction · Computer Science 2025-08-25 Hongqi Li , Yitong Chen , Yujuan Wang , Weihang Ni , Haodong Zhang

Finite element analysis (FEA) forms the cornerstone of modeling cardiac biomechanics but is computationally expensive, limiting its clinical application for digital twin creation, which often requires tens to hundreds of simulations to…

Medical Physics · Physics 2025-04-29 Lei Shi , Yurui Chen , Vijay Vedula

Electromigration, a significant lifetime reliability concern in highperformance integrated circuits, is projected to grow even more important in future heterogeneously integrated systems that will service higher current loads. Today, EM…

Hardware Architecture · Computer Science 2026-03-17 Sachin S. Sapatnekar

Cardiopulmonary exercise testing (CPET) provides a comprehensive assessment of functional capacity by measuring key physiological variables including oxygen consumption ($VO_2$), carbon dioxide production ($VCO_2$), and pulmonary…

Machine Learning · Computer Science 2025-03-19 Muhammet Alkan , Gruschen Veldtman , Fani Deligianni

It is well known that closed-form analytical solutions for AC power flow equations do not exist in general. This paper proposes a multi-dimensional holomorphic embedding method (MDHEM) to obtain an explicit approximate analytical AC…

Systems and Control · Computer Science 2019-03-26 Chengxi Liu , Bin Wang , Xin Xu , Kai Sun , Claus Leth Bak
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