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Related papers: Knowledge-Driven Agentic Scientific Corpus Distill…

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LLM-based agents have emerged as transformative tools capable of executing complex tasks through iterative planning and action, achieving significant advancements in understanding and addressing user needs. Yet, their effectiveness remains…

Human-Computer Interaction · Computer Science 2025-08-26 Mithat Can Ozgun , Jiahuan Pei , Koen Hindriks , Lucia Donatelli , Qingzhi Liu , Junxiao Wang

Large language models (LLMs) have garnered increasing attention owing to their powerful logical reasoning capabilities. Generally, larger LLMs (L-LLMs) that require paid interfaces exhibit significantly superior performance compared to…

Artificial Intelligence · Computer Science 2025-11-11 Dong Chen , Shilin Zhang , Fei Gao , Yueting Zhuang , Siliang Tang , Qidong Liu , Mingliang Xu

Large language models (LLMs) have demonstrated remarkable capabilities across various NLP tasks. However, their computational costs are prohibitively high. To address this issue, previous research has attempted to distill the knowledge of…

Computation and Language · Computer Science 2024-03-12 Chengyuan Liu , Yangyang Kang , Fubang Zhao , Kun Kuang , Zhuoren Jiang , Changlong Sun , Fei Wu

There are two main barriers to using large language models (LLMs) in clinical reasoning. Firstly, while LLMs exhibit significant promise in Natural Language Processing (NLP) tasks, their performance in complex reasoning and planning falls…

Artificial Intelligence · Computer Science 2024-12-31 Shengxin Hong , Liang Xiao , Xin Zhang , Jianxia Chen

Managing scan protocols in Computed Tomography (CT), which includes adjusting acquisition parameters or configuring reconstructions, as well as selecting postprocessing tools in a patient-specific manner, is time-consuming and requires…

Artificial Intelligence · Computer Science 2025-09-25 Xingjian Kang , Linda Vorberg , Andreas Maier , Alexander Katzmann , Oliver Taubmann

Accurate and efficient question-answering systems are essential for delivering high-quality patient care in the medical field. While Large Language Models (LLMs) have made remarkable strides across various domains, they continue to face…

Computation and Language · Computer Science 2025-01-22 Hang Yang , Hao Chen , Hui Guo , Yineng Chen , Ching-Sheng Lin , Shu Hu , Jinrong Hu , Xi Wu , Xin Wang

Building effective clinical decision support systems requires the synthesis of complex heterogeneous multimodal data. Such modalities include temporal electronic health records data, medical images, radiology reports, and clinical notes.…

Artificial Intelligence · Computer Science 2026-05-12 Baraa Al Jorf , Farah E. Shamout

Proprietary large language models (LLMs) embody substantial economic value and are generally exposed only as black-box APIs, yet adversaries can still exploit their outputs to extract knowledge via distillation. Existing defenses focus…

Computation and Language · Computer Science 2026-05-07 Hao Fang , Tianyi Zhang , Tianqu Zhuang , Jiawei Kong , Kuofeng Gao , Bin Chen , Leqi Zheng , Shu-Tao Xia , Ke Xu

We introduce Agentic Reasoning, a framework that enhances large language model (LLM) reasoning by integrating external tool-using agents. Agentic Reasoning dynamically leverages web search, code execution, and structured memory to address…

Artificial Intelligence · Computer Science 2025-07-16 Junde Wu , Jiayuan Zhu , Yuyuan Liu , Min Xu , Yueming Jin

Artificial Intelligence (AI) has increasingly influenced modern society, recently in particular through significant advancements in Large Language Models (LLMs). However, high computational and storage demands of LLMs still limit their…

Computation and Language · Computer Science 2025-04-23 Daniel Hendriks , Philipp Spitzer , Niklas Kühl , Gerhard Satzger

Large Language Models (LLMs) have made significant progress in various fields. However, challenges remain in Multi-Disciplinary Team (MDT) medical consultations. Current research enhances reasoning through role assignment, task…

Artificial Intelligence · Computer Science 2025-03-19 Kai Chen , Xinfeng Li , Tianpei Yang , Hewei Wang , Wei Dong , Yang Gao

Agentic large language models (LLMs) have become prominent for autonomously interacting with external environments and performing multi-step reasoning tasks. Most approaches leverage these capabilities via in-context learning with few-shot…

Computation and Language · Computer Science 2025-10-02 Yawen Xue , Masaya Tsunokake , Yuta Koreeda , Ekant Muljibhai Amin , Takashi Sumiyoshi , Yasuhiro Sogawa

Scientific workflows in computational chemistry and materials science typically involve multiple interdependent steps, such as model preparation, system construction, simulation execution, and data analysis, that researchers have refined…

This project investigates the efficacy of Large Language Models (LLMs) in understanding and extracting scientific knowledge across specific domains and to create a deep learning framework: Knowledge AI. As a part of this framework, we…

Computation and Language · Computer Science 2024-08-12 Balaji Muralidharan , Hayden Beadles , Reza Marzban , Kalyan Sashank Mupparaju

The increasing volume of healthcare textual data requires computationally efficient, yet highly accurate classification approaches able to handle the nuanced and complex nature of medical terminology. This research presents Knowledge…

Computation and Language · Computer Science 2025-05-13 Hajar Sakai , Sarah S. Lam

Computing has long served as a cornerstone of scientific discovery. Recently, a paradigm shift has emerged with the rise of large language models (LLMs), introducing autonomous systems, referred to as agents, that accelerate discovery…

Large language models (LLMs) have demonstrated remarkable performance across a wide range of natural language processing (NLP) tasks. However, these models are often difficult to deploy due to significant computational requirements and…

Computation and Language · Computer Science 2024-12-25 Vijay Goyal , Mustafa Khan , Aprameya Tirupati , Harveer Saini , Michael Lam , Kevin Zhu

Model distillation is a fundamental technique in building large language models (LLMs), transferring knowledge from a teacher model to a student model. However, distillation can lead to model homogenization, reducing diversity among models…

Large language models are moving scientific research from text assistance toward agentic workflows, yet biological research requires strong object validation, methodological suitability, reproducibility, and auditability. Prompt…

Quantitative Methods · Quantitative Biology 2026-05-25 Zhenyu Ma , Yuyang Song , Chunyi Yang , Jingyi Zhu , Limei Xu , Min Xiao , Xukai Jiang

The adoption of machine learning (ML) and deep learning methods has revolutionized molecular medicine by driving breakthroughs in genomics, transcriptomics, drug discovery, and biological systems modeling. The increasing quantity,…