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The rapid evolution of Large Language Models (LLMs) presents a promising solution to the global shortage of mental health professionals. However, their alignment with essential counseling competencies remains underexplored. We introduce…

Large Language Models (LLMs) hold significant promise for improving clinical decision support and reducing physician burnout by synthesizing complex, longitudinal cancer Electronic Health Records (EHRs). However, their implementation in…

Computation and Language · Computer Science 2026-01-12 Dongchen Li , Jitao Liang , Wei Li , Xiaoyu Wang , Longbing Cao , Kun Yu

Large language models (LLMs) are emerging as promising tools for mental health care, offering scalable support through their ability to generate human-like responses. However, the effectiveness of these models in clinical settings remains…

Artificial Intelligence · Computer Science 2024-08-22 Yining Hua , Hongbin Na , Zehan Li , Fenglin Liu , Xiao Fang , David Clifton , John Torous

This paper introduces a system that integrates large language models (LLMs) into the clinical trial retrieval process, enhancing the effectiveness of matching patients with eligible trials while maintaining information privacy and allowing…

Information Retrieval · Computer Science 2024-11-01 Georgios Peikos , Pranav Kasela , Gabriella Pasi

$\textbf{Objectives}$: Large Language Models (LLMs) such as ChatGPT and Med-PaLM have excelled in various medical question-answering tasks. However, these English-centric models encounter challenges in non-English clinical settings,…

Computation and Language · Computer Science 2024-01-31 Jiageng Wu , Xian Wu , Zhaopeng Qiu , Minghui Li , Yingying Zhang , Yefeng Zheng , Changzheng Yuan , Jie Yang

As the performance of large language models (LLMs) continues to advance, their adoption in the medical domain is increasing. However, most existing risk evaluations largely focused on general safety benchmarks. In the medical applications,…

Computation and Language · Computer Science 2026-01-12 Jean-Philippe Corbeil , Minseon Kim , Maxime Griot , Sheela Agarwal , Alessandro Sordoni , Francois Beaulieu , Paul Vozila

Large language models (LLMs) have demonstrated impressive capabilities in natural language understanding and generation, but the quality bar for medical and clinical applications is high. Today, attempts to assess models' clinical knowledge…

Natural Language Processing (NLP) is witnessing a remarkable breakthrough driven by the success of Large Language Models (LLMs). LLMs have gained significant attention across academia and industry for their versatile applications in text…

Computation and Language · Computer Science 2024-04-16 Taojun Hu , Xiao-Hua Zhou

Multimodal Large Language Model (MLLM) relies on the powerful LLM to perform multimodal tasks, showing amazing emergent abilities in recent studies, such as writing poems based on an image. However, it is difficult for these case studies to…

Computer Vision and Pattern Recognition · Computer Science 2025-10-27 Chaoyou Fu , Peixian Chen , Yunhang Shen , Yulei Qin , Mengdan Zhang , Xu Lin , Jinrui Yang , Xiawu Zheng , Ke Li , Xing Sun , Yunsheng Wu , Rongrong Ji , Caifeng Shan , Ran He

There is widespread optimism that frontier Large Language Models (LLMs) and LLM-augmented systems have the potential to rapidly accelerate scientific discovery across disciplines. Today, many benchmarks exist to measure LLM knowledge and…

Objectives: To evaluate the current limitations of large language models (LLMs) in medical question answering, focusing on the quality of datasets used for their evaluation. Materials and Methods: Widely-used benchmark datasets, including…

Computation and Language · Computer Science 2025-07-15 Mahmoud Alwakeel , Aditya Nagori , Vijay Krishnamoorthy , Rishikesan Kamaleswaran

In recent years, Large Language Models (LLMs) have become widely used in medical applications, such as clinical decision support, medical education, and medical question answering. Yet, these models are often English-centric, limiting their…

Computation and Language · Computer Science 2026-02-06 Chaimae Abouzahir , Congbo Ma , Nizar Habash , Farah E. Shamout

Developing artificial intelligence (AI) for clinical research requires a comprehensive data foundation that supports model training and rigorous evaluation. Here, we introduce TrialPanorama, a large-scale structured resource that aggregates…

Artificial Intelligence · Computer Science 2025-12-17 Zifeng Wang , Jiacheng Lin , Qiao Jin , Junyi Gao , Jathurshan Pradeepkumar , Pengcheng Jiang , Zhiyong Lu , Jimeng Sun

Neural surrogate models are powerful and efficient tools in data mining. Meanwhile, large language models (LLMs) have demonstrated remarkable capabilities in code-related tasks, such as generation and understanding. However, an equally…

Machine Learning · Computer Science 2026-05-26 Bohan Lyu , Siqiao Huang , Zichen Liang

Medical large language models (LLMs) research often makes bold claims, from encoding clinical knowledge to reasoning like a physician. These claims are usually backed by evaluation on competitive benchmarks; a tradition inherited from…

Computation and Language · Computer Science 2025-03-17 Ahmed Alaa , Thomas Hartvigsen , Niloufar Golchini , Shiladitya Dutta , Frances Dean , Inioluwa Deborah Raji , Travis Zack

Research on language technology for the development of medical applications is currently a hot topic in Natural Language Understanding and Generation. Thus, a number of large language models (LLMs) have recently been adapted to the medical…

Current Large Language Models (LLMs) benchmarks are often based on open-ended or close-ended QA evaluations, avoiding the requirement of human labor. Close-ended measurements evaluate the factuality of responses but lack expressiveness.…

This paper studies the performance of large language models (LLMs), particularly regarding demographic fairness, in solving real-world healthcare tasks. We evaluate state-of-the-art LLMs with three prevalent learning frameworks across six…

Computation and Language · Computer Science 2024-12-10 Yue Zhou , Barbara Di Eugenio , Lu Cheng

Diabetes is a chronic disease with a significant global health burden, requiring multi-stakeholder collaboration for optimal management. Large language models (LLMs) have shown promise in various healthcare scenarios, but their…

Computation and Language · Computer Science 2025-03-14 Lai Wei , Zhen Ying , Muyang He , Yutong Chen , Qian Yang , Yanzhe Hong , Jiaping Lu , Kaipeng Zheng , Shaoting Zhang , Xiaoying Li , Weiran Huang , Ying Chen

We present DM-Bench, the first benchmark designed to evaluate large language model (LLM) performance across real-world decision-making tasks faced by individuals managing diabetes in their daily lives. Unlike prior health benchmarks that…

Machine Learning · Computer Science 2025-10-06 Maria Ana Cardei , Josephine Lamp , Mark Derdzinski , Karan Bhatia
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