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We present an algorithm for building the extended BWT (eBWT) of a string collection from its grammar-compressed representation. Our technique exploits the string repetitions captured by the grammar to boost the computation of the eBWT.…

Genomics · Quantitative Biology 2021-02-10 Diego Diaz-Dominguez annd Gonzalo Navarro

The Burrows-Wheeler Transform (BWT) is a word transformation introduced in 1994 for Data Compression. It has become a fundamental tool for designing self-indexing data structures, with important applications in several area in science and…

Data Structures and Algorithms · Computer Science 2019-07-05 Raffaele Giancarlo , Giovanni Manzini , Antonio Restivo , Giovanna Rosone , Marinella Sciortino

The boom of genomic sequencing makes compression of set of sequences inescapable. This underlies the need for multi-string indexing data structures that helps compressing the data. The most prominent example of such data structures is the…

Data Structures and Algorithms · Computer Science 2021-11-18 Bastien Cazaux , Eric Rivals

Indexing of very large collections of strings such as those produced by the widespread sequencing technologies, heavily relies on multi-string generalizations of the Burrows-Wheeler Transform (BWT), and for this problem various in-memory…

Data Structures and Algorithms · Computer Science 2016-07-29 Paola Bonizzoni , Gianluca Della Vedova , Serena Nicosia , Marco Previtali , Raffaella Rizzi

The Burrows-Wheeler transform (BWT) is a reversible transform that converts a string $w$ into another string $\mathsf{BWT}(w)$. The size of the run-length encoded BWT (RLBWT) can be interpreted as a measure of repetitiveness in the class of…

Discrete Mathematics · Computer Science 2024-11-19 Hideo Bannai , Tomohiro I , Yuto Nakashima

In recent years, the focus of bioinformatics research has moved from individual sequences to collections of sequences. Given the fundamental role of the Burrows-Wheeler Transform (BWT) in string processing, a number of dedicated tools have…

Data Structures and Algorithms · Computer Science 2025-05-28 Davide Cenzato , Zsuzsanna Lipták

The Burrows-Wheeler-Transform (BWT) is a reversible string transformation which plays a central role in text compression and is fundamental in many modern bioinformatics applications. The BWT is a permutation of the characters, which is in…

Data Structures and Algorithms · Computer Science 2021-03-15 Sara Giuliani , Zsuzsanna Lipták , Francesco Masillo , Romeo Rizzi

Run-length encoding Burrows-Wheeler Transformed strings, resulting in Run-Length BWT (RLBWT), is a powerful tool for processing highly repetitive strings. We propose a new algorithm for online RLBWT working in run-compressed space, which…

Data Structures and Algorithms · Computer Science 2017-10-17 Tatsuya Ohno , Yoshimasa Takabatake , Tomohiro I , Hiroshi Sakamoto

The Burrows-Wheeler-Transform (BWT), a reversible string transformation, is one of the fundamental components of many current data structures in string processing. It is central in data compression, as well as in efficient query algorithms…

Data Structures and Algorithms · Computer Science 2024-04-16 Sara Giuliani , Shunsuke Inenaga , Zsuzsanna Lipták , Nicola Prezza , Marinella Sciortino , Anna Toffanello

It is known that the exact form of the Burrows-Wheeler-Transform (BWT) of a string collection depends, in most implementations, on the input order of the strings in the collection. Reordering strings of an input collection affects the…

Data Structures and Algorithms · Computer Science 2022-12-05 Davide Cenzato , Veronica Guerrini , Zsuzsanna Lipták , Giovanna Rosone

The Burrows-Wheeler Transform (BWT) is often taught in undergraduate courses on algorithmic bioinformatics, because it underlies the FM-index and thus important tools such as Bowtie and BWA. Its admirers consider the BWT a thing of beauty…

Data Structures and Algorithms · Computer Science 2022-08-23 Travis Gagie , Giovanni Manzini , Marinella Sciortino

Motivation: Burrows-Wheeler Transform (BWT) is a common component in full-text indices. Initially developed for data compression, it is particularly powerful for encoding redundant sequences such as pangenome data. However, BWT construction…

Genomics · Quantitative Biology 2025-09-10 Heng Li

Indexing very large collections of strings, such as those produced by the widespread next generation sequencing technologies, heavily relies on multistring generalization of the Burrows-Wheeler Transform (BWT): large requirements of…

Data Structures and Algorithms · Computer Science 2020-12-07 Paola Bonizzoni , Gianluca Della Vedova , Yuri Pirola , Marco Previtali , Raffaella Rizzi

The Burrows-Wheeler transform (BWT) is used by the bzip2 family of compressors. In this paper, we present a hardware architecture that implements an inplace algorithm to compute the BWT. Our design does not have explicit storage for the…

Signal Processing · Electrical Eng. & Systems 2022-09-07 Kleber Stangherlin , Andrew Kennings

Advances in DNA sequencing technology have stimulated the development of algorithms and tools for processing very large collections of short strings (reads). Short-read alignment and assembly are among the most well-studied problems. Many…

Genomics · Quantitative Biology 2014-01-30 Chi-Man Liu , Ruibang Luo , Tak-Wah Lam

In this article we extend the elegant in-place Burrows-Wheeler transform (BWT) algorithm proposed by Crochemore et al. (Crochemore et al., 2015). Our extension is twofold: we first show how to compute simultaneously the longest common…

Data Structures and Algorithms · Computer Science 2018-06-08 Felipe A. Louza , Travis Gagie , Guilherme P. Telles

We present a new scalable, lightweight algorithm to incrementally construct the BWT and FM-index of large string sets such as those produced by Next Generation Sequencing. The algorithm is designed for massive parallelism and can…

Data Structures and Algorithms · Computer Science 2014-10-03 Jacopo Pantaleoni

The Burrows-Wheeler Transform (BWT) is an important technique both in data compression and in the design of compact indexing data structures. It has been generalized from single strings to collections of strings and some classes of labeled…

Data Structures and Algorithms · Computer Science 2019-05-30 Jarno Alanko , Travis Gagie , Gonzalo Navarro , Louisa Seelbach Benkner

The Positional Burrows--Wheeler Transform (PBWT) is a data structure designed for efficiently representing and querying large collections of sequences, such as haplotype panels in genomics. Forward and backward stepping operations --…

Data Structures and Algorithms · Computer Science 2026-02-17 Paola Bonizzoni , Davide Cozzi , Younan Gao

In this paper we study the number $r_{bwt}$ of equal-letter runs produced by the Burrows-Wheeler transform ($BWT$) when it is applied to purely morphic finite words, which are words generated by iterating prolongable morphisms. Such a…

Formal Languages and Automata Theory · Computer Science 2022-02-08 Andrea Frosini , Ilaria Mancini , Simone Rinaldi , Giuseppe Romana , Marinella Sciortino