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Large language models (LLMs) have recently demonstrated their potential in clinical applications, providing valuable medical knowledge and advice. For example, a large dialog LLM like ChatGPT has successfully passed part of the US medical…

Computer Vision and Pattern Recognition · Computer Science 2023-02-15 Sheng Wang , Zihao Zhao , Xi Ouyang , Qian Wang , Dinggang Shen

Vision-language models (VLMs) have gained significant attention in computational pathology due to their multimodal learning capabilities that enhance big-data analytics of giga-pixel whole slide image (WSI). However, their sensitivity to…

Computer Vision and Pattern Recognition · Computer Science 2025-05-02 Vasudev Sharma , Ahmed Alagha , Abdelhakim Khellaf , Vincent Quoc-Huy Trinh , Mahdi S. Hosseini

Seeing clearly with high resolution is a foundation of Large Multimodal Models (LMMs), which has been proven to be vital for visual perception and reasoning. Existing works usually employ a straightforward resolution upscaling method, where…

Computer Vision and Pattern Recognition · Computer Science 2024-06-17 Yi-Fan Zhang , Qingsong Wen , Chaoyou Fu , Xue Wang , Zhang Zhang , Liang Wang , Rong Jin

Many image restoration (IR) tasks require both pixel-level fidelity and high-level semantic understanding to recover realistic photos with fine-grained details. However, previous approaches often struggle to effectively leverage both the…

Computer Vision and Pattern Recognition · Computer Science 2025-12-22 Cuixin Yang , Rongkang Dong , Kin-Man Lam

We propose Context-Adaptive Multi-Prompt Embedding, a novel approach to enrich semantic representations in vision-language contrastive learning. Unlike standard CLIP-style models that rely on a single text embedding, our method introduces…

Machine Learning · Computer Science 2025-08-07 Dahun Kim , Anelia Angelova

The rapidly emerging field of deep learning-based computational pathology has demonstrated promise in developing objective prognostic models from histology whole slide images. However, most prognostic models are either based on histology or…

Computer Vision and Pattern Recognition · Computer Science 2021-08-06 Richard J. Chen , Ming Y. Lu , Drew F. K. Williamson , Tiffany Y. Chen , Jana Lipkova , Muhammad Shaban , Maha Shady , Mane Williams , Bumjin Joo , Zahra Noor , Faisal Mahmood

Whole Slide Images (WSIs) are giga-pixel in scale and are typically partitioned into small instances in WSI classification pipelines for computational feasibility. However, obtaining extensive instance level annotations is costly, making…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Jayanie Bogahawatte , Sachith Seneviratne , Saman Halgamuge

Large-scale pre-trained Vision-Language Models (VLMs), such as CLIP, establish the correlation between texts and images, achieving remarkable success on various downstream tasks with fine-tuning. In existing fine-tuning methods, the…

Computer Vision and Pattern Recognition · Computer Science 2023-07-31 Yi Zhang , Ce Zhang , Yushun Tang , Zhihai He

We present ViDRiP-LLaVA, the first large multimodal model (LMM) in computational pathology that integrates three distinct image scenarios, including single patch images, automatically segmented pathology video clips, and manually segmented…

Computer Vision and Pattern Recognition · Computer Science 2025-10-14 Trinh T. L. Vuong , Jin Tae Kwak

The rapidly emerging field of computational pathology has the potential to enable objective diagnosis, therapeutic response prediction and identification of new morphological features of clinical relevance. However, deep learning-based…

Image and Video Processing · Electrical Eng. & Systems 2020-05-25 Ming Y. Lu , Drew F. K. Williamson , Tiffany Y. Chen , Richard J. Chen , Matteo Barbieri , Faisal Mahmood

Recent rapid progress in the field of computational pathology has been enabled by foundation models. These models are beginning to move beyond encoding image patches towards whole-slide understanding but their clinical utility remains…

Recent advances in multimodal large language models (LLMs) have highlighted their potential for medical and surgical applications. However, existing surgical datasets predominantly adopt a Visual Question Answering (VQA) format with…

Computer Vision and Pattern Recognition · Computer Science 2025-11-27 Tae-Min Choi , Tae Kyeong Jeong , Garam Kim , Jaemin Lee , Yeongyoon Koh , In Cheul Choi , Jae-Ho Chung , Jong Woong Park , Juyoun Park

Pathology is experiencing rapid digital transformation driven by whole-slide imaging and artificial intelligence (AI). While deep learning-based computational pathology has achieved notable success, traditional models primarily focus on…

Self-supervised learning in vision-language processing exploits semantic alignment between imaging and text modalities. Prior work in biomedical VLP has mostly relied on the alignment of single image and report pairs even though clinical…

3D medical image analysis is pivotal in numerous clinical applications. However, the scarcity of labeled data and limited generalization capabilities hinder the advancement of AI-empowered models. Radiology reports are easily accessible and…

Computer Vision and Pattern Recognition · Computer Science 2024-12-10 Xuefeng Ni , Linshan Wu , Jiaxin Zhuang , Qiong Wang , Mingxiang Wu , Varut Vardhanabhuti , Lihai Zhang , Hanyu Gao , Hao Chen

Multimodal Vision Language Models (VLMs) have emerged as a transformative topic at the intersection of computer vision and natural language processing, enabling machines to perceive and reason about the world through both visual and textual…

Computer Vision and Pattern Recognition · Computer Science 2025-04-08 Zongxia Li , Xiyang Wu , Hongyang Du , Fuxiao Liu , Huy Nghiem , Guangyao Shi

Vision-and-language pre-training has achieved impressive success in learning multimodal representations between vision and language. To generalize this success to non-English languages, we introduce UC2, the first machine…

Computer Vision and Pattern Recognition · Computer Science 2021-04-02 Mingyang Zhou , Luowei Zhou , Shuohang Wang , Yu Cheng , Linjie Li , Zhou Yu , Jingjing Liu

End-to-end text-image machine translation (TIMT), which directly translates textual content in images across languages, is crucial for real-world multilingual scene understanding. Despite advances in vision-language large models (VLLMs),…

Computer Vision and Pattern Recognition · Computer Science 2026-03-26 Gengluo Li , Chengquan Zhang , Yupu Liang , Huawen Shen , Yaping Zhang , Pengyuan Lyu , Weinong Wang , Xingyu Wan , Gangyan Zeng , Han Hu , Can Ma , Yu Zhou

Recently, vision-language joint representation learning has proven to be highly effective in various scenarios. In this paper, we specifically adapt vision-language joint learning for scene text detection, a task that intrinsically involves…

Computer Vision and Pattern Recognition · Computer Science 2022-05-02 Sibo Song , Jianqiang Wan , Zhibo Yang , Jun Tang , Wenqing Cheng , Xiang Bai , Cong Yao

Self-supervised vision-language pretraining from pure images and text with a contrastive loss is effective, but ignores fine-grained alignment due to a dual-stream architecture that aligns image and text representations only on a global…

Computer Vision and Pattern Recognition · Computer Science 2022-07-29 Zaid Khan , Vijay Kumar BG , Xiang Yu , Samuel Schulter , Manmohan Chandraker , Yun Fu