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Biopharmaceutical manufacturing is a rapidly growing industry with impact in virtually all branches of medicines. Biomanufacturing processes require close monitoring and control, in the presence of complex bioprocess dynamics with many…

Artificial Intelligence · Computer Science 2022-07-26 Hua Zheng , Wei Xie , Ilya O. Ryzhov , Dongming Xie

Electrical submersible pumps (ESPs) are prevalently utilized as artificial lift systems in the oil and gas industry. These pumps frequently encounter multiphase flows comprising a complex mixture of hydrocarbons, water, and sediments. Such…

Machine Learning · Computer Science 2024-10-03 Felipe de Castro Teixeira Carvalho , Kamaljyoti Nath , Alberto Luiz Serpa , George Em Karniadakis

Biophysical models describing complex, cellular phenomena typically include systems of nonlinear differential equations with many free parameters. While experimental measurements can fix some parameters, those describing internal cellular…

Computational Physics · Physics 2025-07-08 Joseph M. Marcinik , Martín A. Toderi , Dolores Bozovic

Artificial Intelligence is increasingly pervasive across domains, with ever more complex models delivering impressive predictive performance. This fast technological advancement however comes at a concerning environmental cost, with…

Computers and Society · Computer Science 2025-09-25 Emilio Cruciani , Roberto Verdecchia

Modelling, parameter identification, and simulation play an important role in systems biology. Usually, the goal is to determine parameter values that minimise the difference between experimental measurement values and model predictions in…

Mathematical Software · Computer Science 2013-04-10 Thomas Dierkes , Susanna Röblitz , Moritz Wade , Peter Deuflhard

Ecological inference (EI) is the process of learning about individual behavior from aggregate data. We study a partially identified linear contextual effects model for EI and describe how to estimate the district level parameter averaging…

Applications · Statistics 2019-12-11 Wenxin Jiang , Gary King , Allen Schmaltz , Martin A. Tanner

A novel deep learning technique called Physics Informed Neural Networks (PINNs) is adapted to study steady groundwater flow in unconfined aquifers. This technique utilizes information from underlying physics represented in the form of…

Geophysics · Physics 2021-12-28 Mohammad Afzal Shadab , DingCheng Luo , Yiran Shen , Eric Hiatt , Marc Andre Hesse

The development of biophysical models for clinical applications is rapidly advancing in the research community, thanks to their predictive nature and their ability to assist the interpretation of clinical data. However, high-resolution and…

Biologically inspired model (BIM) for image recognition is a robust computational architecture, which has attracted widespread attention. BIM can be described as a four-layer structure based on the mechanisms of the visual cortex. Although…

Computer Vision and Pattern Recognition · Computer Science 2017-10-30 Yan-Feng Lu , Li-Hao Jia , Hong Qaio , Yi Li

Environmental microorganism (EM) offers a high-efficient, harmless, and low-cost solution to environmental pollution. They are used in sanitation, monitoring, and decomposition of environmental pollutants. However, this depends on the…

Computer Vision and Pattern Recognition · Computer Science 2021-02-25 Frank Kulwa , Chen Li , Jinghua Zhang , Kimiaki Shirahama , Sergey Kosov , Xin Zhao , Hongzan Sun , Tao Jiang , Marcin Grzegorzek

We present a new method for enhancing symbolic regression for differential equations via dimensional analysis, specifically Ipsen's and Buckingham pi methods. Since symbolic regression often suffers from high computational costs and…

Machine Learning · Computer Science 2024-11-26 Lena Podina , Diba Darooneh , Joshveer Grewal , Mohammad Kohandel

Biological neurons and their in-silico emulations for neuromorphic artificial intelligence (AI) use extraordinarily energy-efficient mechanisms, such as spike-based communication and local synaptic plasticity. It remains unclear whether…

Neural and Evolutionary Computing · Computer Science 2021-06-17 Timoleon Moraitis , Abu Sebastian , Evangelos Eleftheriou

Biological neural networks can perform complex computations to predict their environment, far above the limited predictive capabilities of individual neurons. While conventional approaches to understanding these computations often focus on…

Neurons and Cognition · Quantitative Biology 2024-06-28 Hanna M. Tolle , Andrea I Luppi , Anil K. Seth , Pedro A. M. Mediano

A challenge in global change biology is to predict how species will respond to future environmental change and to manage these responses. To make such predictions and management actions robust to novel futures, we need to accurately…

Traditional AI methods often rely on task-specific model designs and training, which constrain both the scalability of model size and generalization across different tasks. Here, we introduce ChemFM, a large foundation model specifically…

Computational Engineering, Finance, and Science · Computer Science 2025-11-06 Feiyang Cai , Katelin Zacour , Tianyu Zhu , Tzuen-Rong Tzeng , Yongping Duan , Ling Liu , Srikanth Pilla , Gang Li , Feng Luo

This paper presents a novel physical parameter estimation framework for on-site model characterization, using a two-phase modelling strategy with Physics-Informed Neural Networks (PINNs) and transfer learning (TL). In the first phase, a…

Machine Learning · Computer Science 2026-01-23 Josu Yeregui , Iker Lopetegi , Sergio Fernandez , Erik Garayalde , Unai Iraola

Quantum Fisher Information (QFI) sets the ultimate precision limit for parameter estimation and is therefore a central quantity in quantum metrology. In time-dependent many-body systems, however, maximizing QFI is a highly non-trivial task…

Passive acoustic monitoring has become a key strategy in biodiversity assessment, conservation, and behavioral ecology, especially as Internet-of-Things (IoT) devices enable continuous in situ audio collection at scale. While recent…

Audio and Speech Processing · Electrical Eng. & Systems 2026-02-11 Heitor R. Guimarães , Abhishek Tiwari , Mahsa Abdollahi , Anderson R. Avila , Tiago H. Falk

A brain--machine interface (BMI) based on motor imagery (MI) enables the control of devices using brain signals while the subject imagines performing a movement. It plays a vital role in prosthesis control and motor rehabilitation. To…

Signal Processing · Electrical Eng. & Systems 2024-09-20 Xiaying Wang , Michael Hersche , Michele Magno , Luca Benini

1. Natural sounds have been recorded for millions of hours over the previous decades using passive acoustic monitoring. Improvements in deep learning models have vastly accelerated the analysis of large portions of this data. While new…

Machine Learning · Computer Science 2026-04-14 Vincent S. Kather , Sylvain Haupert , Burooj Ghani , Dan Stowell