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Accelerating the discovery of mechanical properties in combinatorial materials requires autonomous experimentation that accounts for both instrument behavior and experimental cost. Here, an automated nanoindentation (AE-NI) framework is…

Materials Science · Physics 2025-11-24 Vivek Chawla , Stephen Puplampu , Haochen Zhu , Philip D. Rack , Dayakar Penumadu , Sergei Kalinin

As the need for miniaturized structural and functional materials has increased,the need for precise materials characterizaton has also expanded. Nanoindentation is a popular method that can be used to measure material mechanical behavior…

Accelerating the discovery of structural materials is essential for applications in hard and refractory alloys, hypersonic platforms, nuclear systems, and other extreme environment technologies. Progress is often constrained by slow…

Materials Science · Physics 2025-12-16 Vivek Chawla , Dayakar Penumadu , Sergei Kalinin

Nanoparticle superlattices consisting of ordered arrangements of nanoparticles exhibit unique optical, magnetic, and electronic properties arising from nanoparticle characteristics as well as their collective behaviors. Understanding how…

Materials Science · Physics 2025-01-09 Aanish Paruchuri , Carl Thrasher , A. J. Hart , Robert Macfarlane , Arthi Jayaraman

Precise assessment of the mechanical properties of soft biological systems at the nanoscale is crucial for understanding physiology, pathology, and developing relevant drugs. Conventional atomic force microscopy (AFM)-based indentation…

Biological Physics · Physics 2024-08-21 Yue Cui , Weng-Hang Leong , Guoli Zhu , Ren-Bao Liu , Quan Li

A method for automated quantification of the alignment of one-dimensional nanostructures from microscopy imaging is presented. Nanostructure alignment metrics are formulated and shown to able to rigorously quantify the orientational order…

Instrumentation and Detectors · Physics 2016-08-03 Jianjin Dong , Irene A. Goldthorpe , Nasser Mohieddin Abukhdeir

Accurate surface roughness prediction is critical for ensuring high product quality, especially in areas like manufacturing and aerospace, where the smallest imperfections can compromise performance or safety. However, this is challenging…

Computational Engineering, Finance, and Science · Computer Science 2024-05-29 Penghui Ruan , Divya Saxena , Jiannong Cao , Xiaoyun Liu , Ruoxin Wang , Chi Fai Cheung

Accurately measuring the size, morphology, and structure of nanoparticles is very important, because they are strongly dependent on their properties for many applications. In this paper, we present a deep-learning based method for…

Materials Science · Physics 2022-07-29 Claudius Zelenka , Marius Kamp , Kolja Strohm , Akram Kadoura , Jacob Johny , Reinhard Koch , Lorenz Kienle

Autofocus (AF) methods are extensively used in biomicroscopy, for example to acquire timelapses, where the imaged objects tend to drift out of focus. AD algorithms determine an optimal distance by which to move the sample back into the…

Image and Video Processing · Electrical Eng. & Systems 2021-01-14 Adrian Shajkofci , Michael Liebling

Automated decision-making is becoming key for automated characterization including electron and scanning probe microscopies and nano indentation. Most machine learning driven workflows optimize a single predefined objective and tend to…

Materials Science · Physics 2026-04-07 Kamyar Barakati , Boris N. Slautin , Utkarsh Pratiush , Hiroshi Funakubo , Sergei V. Kalinin

Three-dimensional facial stereophotogrammetry provides a detailed representation of craniofacial soft tissue without the use of ionizing radiation. While manual annotation of landmarks serves as the current gold standard for cephalometric…

Computer Vision and Pattern Recognition · Computer Science 2025-06-18 Bo Berends , Freek Bielevelt , Ruud Schreurs , Shankeeth Vinayahalingam , Thomas Maal , Guido de Jong

This study proposes an automated data mining framework based on autoencoders and experimentally verifies its effectiveness in feature extraction and data dimensionality reduction. Through the encoding-decoding structure, the autoencoder can…

Machine Learning · Computer Science 2024-12-04 Yaxin Liang , Xinshi Li , Xin Huang , Ziqi Zhang , Yue Yao

Next-generation integrated nanophotonic device designs leverage advanced optimization techniques such as inverse design and topology optimization which achieve high performance and extreme miniaturization by optimizing a massively complex…

Machine Learning · Computer Science 2023-03-23 Dusan Gostimirovic , Yuri Grinberg , Dan-Xia Xu , Odile Liboiron-Ladouceur

In this study, Cu-Cr composites were studied by nanoindentation. Arrays of indents were placed over large areas of the samples resulting in datasets consisting of several hundred measurements of Young's modulus and hardness at varying…

Machine Learning · Computer Science 2023-09-14 Chen Zhang , Clémence Bos , Stefan Sandfeld , Ruth Schwaiger

A method is presented for the registration and correlation of intrinsic property maps of materials, including data from nanoindentation hardness, Electron Back-Scattered Diffraction (EBSD), Electron Micro-Probe Analysis (EPMA). This highly…

Materials Science · Physics 2021-01-05 C. M. Magazzeni , H. M. Gardner , I. Howe , P. Gopon , J. C. Waite , D. Rugg , D. E. J. Armstrong , A. J. Wilkinson

Adapting pre-trained foundation models for various downstream tasks has been prevalent in artificial intelligence. Due to the vast number of tasks and high costs, adjusting all parameters becomes unfeasible. To mitigate this, several…

Computer Vision and Pattern Recognition · Computer Science 2025-02-07 Chongjie Si , Xuehui Wang , Xue Yang , Zhengqin Xu , Qingyun Li , Jifeng Dai , Yu Qiao , Xiaokang Yang , Wei Shen

Nanoparticles occur in various environments as a consequence of man-made processes, which raises concerns about their impact on the environment and human health. To allow for proper risk assessment, a precise and statistically relevant…

Precise sensor calibration is critical for autonomous vehicles as a prerequisite for perception algorithms to function properly. Rotation error of one degree can translate to position error of meters in target object detection at large…

Robotics · Computer Science 2025-06-24 Zhongyuan Li , Honggang Gou , Ping Li , Jiaotong Guo , Mao Ye

Accurately tracking particles and determining their coordinate along the optical axis is a major challenge in optical microscopy, especially when extremely high precision is needed. In this study, we introduce a deep learning approach using…

Image and Video Processing · Electrical Eng. & Systems 2025-08-05 Andrey Alexandrov , Giovanni Acampora , Giovanni De Lellis , Antonia Di Crescenzo , Chiara Errico , Daria Morozova , Valeri Tioukov , Autilia Vittiello

The continuous development of new multiphase alloys with improved mechanical properties requires quantitative microstructure-resolved observation of the nanoscale deformation mechanisms at, e.g., multiphase interfaces. This calls for a…

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