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In order to understand the complexities of cellular biology, researchers are interested in two important metrics: the genetic expression information of cells and their spatial coordinates within a tissue sample. However, state-of-the art…

Machine Learning · Computer Science 2023-11-02 J. Ding , S. N. Zaman , P. Y. Chen , D. Wang

Inspired by recent findings that generative diffusion models learn semantically meaningful representations, we use them to discover the intrinsic hierarchical structure in biomedical 3D images using unsupervised segmentation. We show that…

Computer Vision and Pattern Recognition · Computer Science 2023-10-11 Nurislam Tursynbek , Marc Niethammer

Multi-cell cooperation is a promising approach for mitigating inter-cell interference in dense cellular networks. Quantifying the performance of multi-cell cooperation is challenging as it integrates physical-layer techniques and network…

Information Theory · Computer Science 2011-03-23 Kaibin Huang , Jeffrey G. Andrews

Spatial correlations of the cubic 3-torus topology are analysed using the Planck 2013 data. The spatial-correlation method for detecting multiply connected spaces is based on the fact that positions on the cosmic microwave background (CMB)…

Cosmology and Nongalactic Astrophysics · Physics 2015-08-06 R. Aurich

Living systems exhibit complex yet organized behavior on multiple spatiotemporal scales. To investigate the nature of multiscale coordination in living systems, one needs a meaningful and systematic way to quantify the complex dynamics, a…

Adaptation and Self-Organizing Systems · Physics 2020-03-11 Mengsen Zhang , William D. Kalies , J. A. Scott Kelso , Emmanuelle Tognoli

Cross-lingual topic modeling seeks to uncover coherent and semantically aligned topics across languages - a task central to multilingual understanding. Yet most existing models learn topics in disjoint, language-specific spaces and rely on…

Computation and Language · Computer Science 2026-01-21 Nguyen Tien Phat , Ngo Vu Minh , Linh Van Ngo , Nguyen Thi Ngoc Diep , Thien Huu Nguyen

Spatial transcriptomics methods capture cellular measurements such as gene expression and cell types at specific locations in a cell, helping provide a localized picture of tissue health. Traditional visualization techniques superimpose the…

Quantitative Methods · Quantitative Biology 2024-10-16 Siyuan Zhao , G. Elisabeta Marai

Spatial proteomics technologies have transformed our understanding of complex tissue architecture in cancer but present unique challenges for computational analysis. Each study uses a different marker panel and protocol, and most methods…

In recent years, disease mapping studies have become a routine application within geographical epidemiology and are typically analysed within a Bayesian hierarchical model formulation. A variety of model formulations for the latent level…

Methodology · Statistics 2016-01-07 Andrea Riebler , Sigrunn H. Sørbye , Daniel Simpson , Håvard Rue

This work studies lung tumor growth prediction from sparse and irregular longitudinal computed tomography (CT) observations with measurement variability. A Bayesian physics-informed neural network is developed by combining Gompertz growth…

Machine Learning · Computer Science 2026-05-14 Lingfei Kong , Haoran Ma

Images and structured tables are essential parts of real-world databases. Though tabular-image representation learning is promising to create new insights, it remains a challenging task, as tabular data is typically heterogeneous and…

Computer Vision and Pattern Recognition · Computer Science 2024-07-11 Siyi Du , Shaoming Zheng , Yinsong Wang , Wenjia Bai , Declan P. O'Regan , Chen Qin

In order to perform complex actions in human environments, an autonomous robot needs the ability to understand the environment, that is, to gather and maintain spatial knowledge. Topological map is commonly used for representing large…

Robotics · Computer Science 2017-07-11 Kaiyu Zheng

In this paper we propose a unified framework to simultaneously discover the number of clusters and group the data points into them using subspace clustering. Real data distributed in a high-dimensional space can be disentangled into a union…

Computer Vision and Pattern Recognition · Computer Science 2019-07-24 Jie Liang , Jufeng Yang , Ming-Ming Cheng , Paul L. Rosin , Liang Wang

Generating interpretable visualizations from complex data is a common problem in many applications. Two key ingredients for tackling this issue are clustering and representation learning. However, current methods do not yet successfully…

Machine Learning · Computer Science 2020-06-11 Laura Manduchi , Matthias Hüser , Julia Vogt , Gunnar Rätsch , Vincent Fortuin

Accurate quantification of the extent of lung pathological patterns (fibrosis, ground-glass opacity, emphysema, consolidation) is prerequisite for diagnosis and follow-up of interstitial lung diseases. However, segmentation is challenging…

Image and Video Processing · Electrical Eng. & Systems 2025-01-08 Rezkellah Noureddine Khiati , Pierre-Yves Brillet , Radu Ispas , Catalin Fetita

Topology-consistent dynamic model sequences are essential for applications such as animation and model editing. However, existing 4D reconstruction methods face challenges in generating high-quality topology-consistent meshes. To address…

Graphics · Computer Science 2025-12-02 Hanzhi Guo , Dongdong Weng , Mo Su , Yixiao Chen , Xiaonuo Dongye , Chenyu Xu

This paper presents novel strategies for spawning and fusing submaps within an elastic dense 3D reconstruction system. The proposed system uses spatial understanding of the scanned environment to control memory usage growth by fusing…

Robotics · Computer Science 2021-09-21 Yiduo Wang , Milad Ramezani , Matias Mattamala , Maurice Fallon

Anatomy evaluation is crucial for understanding the physiological state, diagnosing abnormalities, and guiding medical interventions. Statistical shape modeling (SSM) is vital in this process. By enabling the extraction of quantitative…

Computer Vision and Pattern Recognition · Computer Science 2025-02-12 Krithika Iyer , Mokshagna Sai Teja Karanam , Shireen Elhabian

Self-supervised learning (SSL) has emerged as a promising paradigm for addressing the annotation bottleneck in medical imaging by learning representations from unlabeled data. However, its effectiveness depends heavily on the design of the…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Chathura Wimalasiri

Characterization of topology and dimensionality of spectral feature spaces provides insight into information content. The objective of this study is to characterize topology and spectral dimensionality of spectral mixing spaces representing…

Geophysics · Physics 2023-07-11 Christopher Small , Daniel Sousa