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Electronic Health Records (EHR)-based disease prediction models have demonstrated significant clinical value in promoting precision medicine and enabling early intervention. However, existing large language models face two major challenges:…

Computation and Language · Computer Science 2025-06-19 Junke Wang , Hongshun Ling , Li Zhang , Longqian Zhang , Fang Wang , Yuan Gao , Zhi Li

Understanding deep learning model behavior is critical to accepting machine learning-based decision support systems in the medical community. Previous research has shown that jointly using clinical notes with electronic health record (EHR)…

Machine Learning · Computer Science 2022-12-07 Severin Husmann , Hugo Yèche , Gunnar Rätsch , Rita Kuznetsova

Irregular sampling and high missingness are intrinsic challenges in modeling time series derived from electronic health records (EHRs),where clinical variables are measured at uneven intervals depending on workflow and intervention timing.…

Machine Learning · Computer Science 2025-09-29 Jeong Eul Kwon , Joo Heung Yoon , Hyo Kyung Lee

The widespread application of Electronic Health Records (EHR) data in the medical field has led to early successes in disease risk prediction using deep learning methods. These methods typically require extensive data for training due to…

Machine Learning · Computer Science 2024-11-28 Shibo Li , Hengliang Cheng , Weihua Li

Clinical trials are a systematic endeavor to assess the safety and efficacy of new drugs or treatments. Conducting such trials typically demands significant financial investment and meticulous planning, highlighting the need for accurate…

Machine Learning · Computer Science 2025-11-03 Tien Huu Do , Antoine Masquelier , Nae Eoun Lee , Jonathan Crowther

While pre-trained language models (PTLMs) have achieved noticeable success on many NLP tasks, they still struggle for tasks that require event temporal reasoning, which is essential for event-centric applications. We present a continual…

Computation and Language · Computer Science 2021-09-20 Rujun Han , Xiang Ren , Nanyun Peng

Speech perception involves storing and integrating sequentially presented items. Recent work in cognitive neuroscience has identified temporal and contextual characteristics in humans' neural encoding of speech that may facilitate this…

Computation and Language · Computer Science 2024-05-15 Oli Danyi Liu , Hao Tang , Naomi Feldman , Sharon Goldwater

Self-supervised learning in vision-language processing exploits semantic alignment between imaging and text modalities. Prior work in biomedical VLP has mostly relied on the alignment of single image and report pairs even though clinical…

Electronic Health Records (EHRs) provide vital contextual information to radiologists and other physicians when making a diagnosis. Unfortunately, because a given patient's record may contain hundreds of notes and reports, identifying…

Understanding the relationships between biomedical terms like viruses, drugs, and symptoms is essential in the fight against diseases. Many attempts have been made to introduce the use of machine learning to the scientific process of…

Machine Learning · Computer Science 2024-03-14 Uchenna Akujuobi , Jun Chen , Mohamed Elhoseiny , Michael Spranger , Xiangliang Zhang

Electronic Health Records (EHRs) contain rich yet complex information, and their automated analysis is critical for clinical decision-making. Despite recent advances of large language models (LLMs) in clinical workflows, their ability to…

Computation and Language · Computer Science 2025-11-26 Yusheng Liao , Chaoyi Wu , Junwei Liu , Shuyang Jiang , Pengcheng Qiu , Haowen Wang , Yun Yue , Shuai Zhen , Jian Wang , Qianrui Fan , Jinjie Gu , Ya Zhang , Yanfeng Wang , Yu Wang , Weidi Xie

While deep learning techniques have shown promising results in many natural language processing (NLP) tasks, it has not been widely applied to the clinical domain. The lack of large datasets and the pervasive use of domain-specific language…

Computation and Language · Computer Science 2019-06-20 Jiin Nam , Seunghyun Yoon , Kyomin Jung

Due to their similarity-based learning objectives, pretrained sentence encoders often internalize stereotypical assumptions that reflect the social biases that exist within their training corpora. In this paper, we describe several kinds of…

Computation and Language · Computer Science 2023-03-13 Hongyin Luo , James Glass

This study introduces a novel knowledge enhanced tokenisation mechanism, K-Tokeniser, for clinical text processing. Technically, at initialisation stage, K-Tokeniser populates global representations of tokens based on semantic types of…

Computation and Language · Computer Science 2024-06-21 Abul Hasan , Jinge Wu , Quang Ngoc Nguyen , Salomé Andres , Imane Guellil , Huayu Zhang , Arlene Casey , Beatrice Alex , Bruce Guthrie , Honghan Wu

Temporal reasoning over tabular data presents substantial challenges for large language models (LLMs), as evidenced by recent research. In this study, we conduct a comprehensive analysis of temporal datasets to pinpoint the specific…

Computation and Language · Computer Science 2024-07-24 Irwin Deng , Kushagra Dixit , Vivek Gupta , Dan Roth

Emerging diseases present challenges in symptom recognition and timely clinical intervention due to limited available information. An effective prognostic model could assist physicians in making accurate diagnoses and designing personalized…

Machine Learning · Computer Science 2025-02-12 Zhongji Zhang , Yuhang Wang , Yinghao Zhu , Xinyu Ma , Yasha Wang , Junyi Gao , Liantao Ma , Wen Tang , Xiaoyun Zhang , Ling Wang

Unsupervised pretraining is an integral part of many natural language processing systems, and transfer learning with language models has achieved remarkable results in many downstream tasks. In the clinical application of medical code…

Computation and Language · Computer Science 2022-06-03 Shaoxiong Ji , Matti Hölttä , Pekka Marttinen

Traditional diagnosis of chronic diseases involves in-person consultations with physicians to identify the disease. However, there is a lack of research focused on predicting and developing application systems using clinical notes and blood…

Software Engineering · Computer Science 2024-06-27 Chun-Chieh Liao , Wei-Ting Kuo , I-Hsuan Hu , Yen-Chen Shih , Jun-En Ding , Feng Liu , Fang-Ming Hung

Learning to associate audio with textual descriptions is valuable for a range of tasks, including pretraining, zero-shot classification, audio retrieval, audio captioning, and text-conditioned audio generation. Existing contrastive…

Audio and Speech Processing · Electrical Eng. & Systems 2025-05-13 Paul Primus , Florian Schmid , Gerhard Widmer

We propose to meta-learn an a self-supervised patient trajectory forecast learning rule by meta-training on a meta-objective that directly optimizes the utility of the patient representation over the subsequent clinical outcome prediction.…

Machine Learning · Computer Science 2024-07-30 Yuan Xue , Nan Du , Anne Mottram , Martin Seneviratne , Andrew M. Dai