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Group relative policy optimization (GRPO) has become a standard post-training paradigm for improving reasoning and preference alignment in large language models (LLMs), and has recently shown strong effectiveness in LLM-based recommender…

Information Retrieval · Computer Science 2026-03-09 Yu Wang , Yonghui Yang , Le Wu , Jiancan Wu , Hefei Xu , Hui Lin

Large Language Models (LLMs) are increasingly deployed in business-critical domains such as finance, education, healthcare, and customer support, where users expect consistent and reliable recommendations. Yet LLMs often exhibit variability…

Machine Learning · Computer Science 2026-04-20 Sonal Prabhune , Balaji Padmanabhan , Kaushik Dutta

Multimodal large language models have advanced rapidly, but their adoption in medicine is constrained by limited domain coverage, imperfect modality alignment, and insufficient grounded reasoning. We introduce MedMO, a medical multimodal…

Computer Vision and Pattern Recognition · Computer Science 2026-03-13 Ankan Deria , Komal Kumar , Adinath Madhavrao Dukre , Eran Segal , Salman Khan , Imran Razzak

Iterative preference optimization methods have recently been shown to perform well for general instruction tuning tasks, but typically make little improvement on reasoning tasks (Yuan et al., 2024, Chen et al., 2024). In this work we…

Computation and Language · Computer Science 2024-06-27 Richard Yuanzhe Pang , Weizhe Yuan , Kyunghyun Cho , He He , Sainbayar Sukhbaatar , Jason Weston

Reasoning models leverage inference-time compute to significantly enhance the performance of language models on difficult logical tasks, and have become a dominating paradigm in frontier LLMs. Despite their wide adoption, the mechanisms…

Machine Learning · Computer Science 2025-11-11 Jake Ward , Paul Riechers , Adam Shai

The advancement of Large Vision-Language Models (LVLMs) has propelled their application in the medical field. However, Medical LVLMs (Med-LVLMs) encounter factuality challenges due to modality misalignment, where the models prioritize…

Computer Vision and Pattern Recognition · Computer Science 2025-06-05 Kangyu Zhu , Peng Xia , Yun Li , Hongtu Zhu , Sheng Wang , Huaxiu Yao

Standard human preference-based alignment methods, such as Reinforcement Learning from Human Feedback (RLHF), are a cornerstone for aligning large language models (LLMs) with human values. However, these methods typically assume that…

Artificial Intelligence · Computer Science 2026-03-02 Xiaoyang Cao , Zelai Xu , Mo Guang , Kaiwen Long , Michiel A. Bakker , Yu Wang , Chao Yu

The rapid advancement of large language models (LLMs) has facilitated their transformation into conversational chatbots that can grasp contextual nuances and generate pertinent sentences, closely mirroring human values through advanced…

Computation and Language · Computer Science 2024-07-19 Janghwan Lee , Seongmin Park , Sukjin Hong , Minsoo Kim , Du-Seong Chang , Jungwook Choi

Large language models (LLMs) have exhibited impressive reasoning abilities on a wide range of complex tasks. However, enhancing these capabilities through post-training remains resource intensive, particularly in terms of data and…

Artificial Intelligence · Computer Science 2025-08-13 Shuo Cai , Su Lu , Qi Zhou , Kejing Yang , Zhijie Sang , Congkai Xie , Hongxia Yang

Multimodal large language models (MLLMs) hold considerable promise for applications in healthcare. However, their deployment in safety-critical settings is hindered by two key limitations: (i) sensitivity to prompt design, and (ii) a…

Computer Vision and Pattern Recognition · Computer Science 2025-10-14 Anita Kriz , Elizabeth Laura Janes , Xing Shen , Tal Arbel

Large Language Models (LLMs) have emerged as transformative tools in the healthcare sector, demonstrating remarkable capabilities in natural language understanding and generation. However, their proficiency in numerical reasoning,…

Artificial Intelligence · Computer Science 2025-01-27 Arjun R. Malghan

Recent advances in large language models (LLMs), such as OpenAI-o1 and DeepSeek-R1, have demonstrated the effectiveness of test-time scaling, where extended reasoning processes substantially enhance model performance. Despite this, current…

Computation and Language · Computer Science 2025-03-26 Xiaoyu Tian , Sitong Zhao , Haotian Wang , Shuaiting Chen , Yunjie Ji , Yiping Peng , Han Zhao , Xiangang Li

Purpose: The performance of three different large language models (LLMS) (GPT-3.5, GPT-4, and PaLM2) in answering ophthalmology professional questions was evaluated and compared with that of three different professional populations (medical…

Computation and Language · Computer Science 2023-11-10 Jason Holmes , Shuyuan Ye , Yiwei Li , Shi-Nan Wu , Zhengliang Liu , Zihao Wu , Jinyu Hu , Huan Zhao , Xi Jiang , Wei Liu , Hong Wei , Jie Zou , Tianming Liu , Yi Shao

Clinical document classification is essential for converting unstructured medical texts into standardised ICD-10 diagnoses, yet it faces challenges due to complex medical language, privacy constraints, and limited annotated datasets. Large…

Computation and Language · Computer Science 2026-02-03 Akram Mustafa , Usman Naseem , Mostafa Rahimi Azghadi

Mathematical reasoning has been challenging for large language models (LLMs), and the introduction of step-by-step Chain-of-Thought (CoT) inference has significantly advanced the mathematical capabilities of LLMs. However, current…

Artificial Intelligence · Computer Science 2025-09-23 Lang Cao , Yingtian Zou , Chao Peng , Renhong Chen , Wu Ning , Yitong Li

In the field of medicine, complex reasoning tasks such as clinical diagnosis, treatment planning, and medical knowledge integration pose significant challenges, where small language models often underperform compared to large language…

Computation and Language · Computer Science 2025-09-30 Xinchun Su , Chunxu Luo , Yixuan Li , Weidong Yang , Lipeng Ma

High-performing medical Large Language Models (LLMs) typically require extensive fine-tuning with substantial computational resources, limiting accessibility for resource-constrained healthcare institutions. This study introduces a…

Computation and Language · Computer Science 2025-10-17 Ziad Elshaer , Essam A. Rashed

Multimodal Large Language Models (MLLMs) have achieved remarkable progress in domains such as visual understanding and mathematical reasoning. However, their application in the medical domain is constrained by two key challenges: (1)…

Computation and Language · Computer Science 2025-10-09 Zeyu Liu , Zhitian Hou , Guanghao Zhu , Zhijie Sang , Congkai Xie , Hongxia Yang

Reinforcement Learning (RL) has significantly improved large language model reasoning, but existing RL fine-tuning methods rely heavily on heuristic techniques such as entropy regularization and reweighting to maintain stability. In…

Computation and Language · Computer Science 2026-05-26 Shiqi Liu , Zeyu He , Guojian Zhan , Letian Tao , Zhilong Zheng , Jiang Wu , Yinuo Wang , Yang Guan , Kehua Sheng , Bo Zhang , Keqiang Li , Jingliang Duan , Shengbo Eben Li

Recent advancements in large language models (LLMs) have shown promise in medical applications such as disease diagnosis and treatment planning. However, most existing medical LLMs struggle with the deep reasoning required for complex…

Computation and Language · Computer Science 2025-07-31 Hongzhou Yu , Tianhao Cheng , Yingwen Wang , Wen He , Qing Wang , Ying Cheng , Yuejie Zhang , Rui Feng , Xiaobo Zhang