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Electronic health records (EHR) contain a wealth of biomedical information, serving as valuable resources for the development of precision medicine systems. However, privacy concerns have resulted in limited access to high-quality and…

Machine Learning · Computer Science 2024-03-26 Hongyi Yuan , Songchi Zhou , Sheng Yu

Due to patient privacy protection concerns, machine learning research in healthcare has been undeniably slower and limited than in other application domains. High-quality, realistic, synthetic electronic health records (EHRs) can be…

Machine Learning · Computer Science 2023-02-10 Huan He , Shifan Zhao , Yuanzhe Xi , Joyce C Ho

Electronic Health Records (EHRs) are rich sources of patient-level data, offering valuable resources for medical data analysis. However, privacy concerns often restrict access to EHRs, hindering downstream analysis. Current EHR…

Machine Learning · Computer Science 2024-12-03 Muhang Tian , Bernie Chen , Allan Guo , Shiyi Jiang , Anru R. Zhang

Electronic health records (EHRs) are invaluable for clinical research, yet privacy concerns severely restrict data sharing. Synthetic data generation offers a promising solution, but EHRs present unique challenges: they contain both…

Machine Learning · Computer Science 2026-03-26 Shaonan Liu , Yuichiro Iwashita , Soichiro Nakako , Masakazu Iwamura , Koichi Kise

Synthesizing electronic health records (EHR) data has become a preferred strategy to address data scarcity, improve data quality, and model fairness in healthcare. However, existing approaches for EHR data generation predominantly rely on…

Machine Learning · Computer Science 2024-06-21 Yuan Zhong , Xiaochen Wang , Jiaqi Wang , Xiaokun Zhang , Yaqing Wang , Mengdi Huai , Cao Xiao , Fenglong Ma

The scarcity of large-scale and high-quality electronic health records (EHRs) remains a major bottleneck in biomedical research, especially as large foundation models become increasingly data-hungry. Synthesizing substantial volumes of…

Machine Learning · Computer Science 2025-08-05 Yandong Yan , Chenxi Li , Yu Huang , Dexuan Xu , Jiaqi Zhu , Zhongyan Chai , Huamin Zhang

We present a novel framework for leveraging synthetic ICU time-series data not only to train but also to rigorously and trustworthily evaluate predictive models, both at the population level and within fine-grained demographic subgroups.…

Machine Learning · Computer Science 2025-10-23 Mahmoud Ibrahim , Bart Elen , Chang Sun , Gökhan Ertaylan , Michel Dumontier

Electronic Health Records (EHRs) contain sensitive patient information, which presents privacy concerns when sharing such data. Synthetic data generation is a promising solution to mitigate these risks, often relying on deep generative…

Machine Learning · Computer Science 2023-08-11 Taha Ceritli , Ghadeer O. Ghosheh , Vinod Kumar Chauhan , Tingting Zhu , Andrew P. Creagh , David A. Clifton

Survival analysis is a cornerstone of clinical research by modeling time-to-event outcomes such as metastasis, disease relapse, or patient death. Unlike standard tabular data, survival data often come with incomplete event information due…

Machine Learning · Computer Science 2026-02-06 Marie Brockschmidt , Maresa Schröder , Stefan Feuerriegel

Diffusion models have achieved state-of-the-art performance in generative modeling tasks across various domains. Prior works on time series diffusion models have primarily focused on developing conditional models tailored to specific…

Machine Learning · Computer Science 2023-11-23 Marcel Kollovieh , Abdul Fatir Ansari , Michael Bohlke-Schneider , Jasper Zschiegner , Hao Wang , Yuyang Wang

In the field of behavior-related brain computation, it is necessary to align raw neural signals against the drastic domain shift among them. A foundational framework within neuroscience research posits that trial-based neural population…

Neurons and Cognition · Quantitative Biology 2024-03-12 Yule Wang , Zijing Wu , Chengrui Li , Anqi Wu

Imputation of missing images via source-to-target modality translation can improve diversity in medical imaging protocols. A pervasive approach for synthesizing target images involves one-shot mapping through generative adversarial networks…

Image and Video Processing · Electrical Eng. & Systems 2023-04-03 Muzaffer Özbey , Onat Dalmaz , Salman UH Dar , Hasan A Bedel , Şaban Özturk , Alper Güngör , Tolga Çukur

Diffusion models have shown great promise in data generation, yet generating time series data remains challenging due to the need to capture complex temporal dependencies and structural patterns. In this paper, we present \textit{TSGDiff},…

Machine Learning · Computer Science 2025-11-18 Lifeng Shen , Xuyang Li , Lele Long

Electronic health records (EHRs) are a pivotal data source that enables numerous applications in computational medicine, e.g., disease progression prediction, clinical trial design, and health economics and outcomes research. Despite wide…

Machine Learning · Computer Science 2024-06-18 Jun Han , Zixiang Chen , Yongqian Li , Yiwen Kou , Eran Halperin , Robert E. Tillman , Quanquan Gu

High-resolution time series data are crucial for the operation and planning of energy systems such as electrical power systems and heating systems. Such data often cannot be shared due to privacy concerns, necessitating the use of synthetic…

Machine Learning · Computer Science 2025-06-19 Nan Lin , Peter Palensky , Pedro P. Vergara

Generating high-quality synthetic time series is a fundamental yet challenging task across domains such as forecasting and anomaly detection, where real data can be scarce, noisy, or costly to collect. Unlike static data generation,…

Machine Learning · Computer Science 2025-09-25 MohammadReza EskandariNasab , Shah Muhammad Hamdi , Soukaina Filali Boubrahimi

Health risk prediction is one of the fundamental tasks under predictive modeling in the medical domain, which aims to forecast the potential health risks that patients may face in the future using their historical Electronic Health Records…

Machine Learning · Computer Science 2023-10-09 Yuan Zhong , Suhan Cui , Jiaqi Wang , Xiaochen Wang , Ziyi Yin , Yaqing Wang , Houping Xiao , Mengdi Huai , Ting Wang , Fenglong Ma

This paper introduces DrDiff, a novel framework for long-text generation that overcomes the efficiency-quality trade-off through three core technologies. First, we design a dynamic expert scheduling mechanism that intelligently allocates…

Computation and Language · Computer Science 2025-10-14 Jusheng Zhang , Yijia Fan , Kaitong Cai , Zimeng Huang , Xiaofei Sun , Jian Wang , Chengpei Tang , Keze Wang

Among various aspects of ensuring the responsible design of AI tools for healthcare applications, addressing fairness concerns has been a key focus area. Specifically, given the wide spread of electronic health record (EHR) data and their…

Machine Learning · Computer Science 2025-06-30 Mirza Farhan Bin Tarek , Raphael Poulain , Rahmatollah Beheshti

The expansion of Artificial Intelligence-generated content service requires diffusion model serving to simultaneously achieve high throughput and low task end-to-end (E2E) latency. However, existing continuous batching methods suffer from…

Artificial Intelligence · Computer Science 2026-05-12 Ziqi Zhou , Peng Yang , Yuxin Liang , Mingliu Liu , Jia Lu
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