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Foundation models (FMs) are catalyzing a transformative shift in materials science (MatSci) by enabling scalable, general-purpose, and multimodal AI systems for scientific discovery. Unlike traditional machine learning models, which are…

Machine Learning · Computer Science 2025-06-27 Minh-Hao Van , Prateek Verma , Chen Zhao , Xintao Wu

While reinforcement learning from scratch has shown impressive results in solving sequential decision-making tasks with efficient simulators, real-world applications with expensive interactions require more sample-efficient agents.…

Machine Learning · Computer Science 2025-09-22 Remo Sasso , Michelangelo Conserva , Dominik Jeurissen , Paulo Rauber

Foundation models (FMs), large neural networks pretrained on extensive and diverse datasets, have revolutionized artificial intelligence and shown significant promise in medical imaging by enabling robust performance with limited labeled…

Image and Video Processing · Electrical Eng. & Systems 2025-06-17 Salah Ghamizi , Georgia Kanli , Yu Deng , Magali Perquin , Olivier Keunen

Deep Neural Networks (DNNs) lack robustness against imperceptible perturbations to their input. Face Recognition Models (FRMs) based on DNNs inherit this vulnerability. We propose a methodology for assessing and characterizing the…

Computer Vision and Pattern Recognition · Computer Science 2022-02-11 Juan C. Pérez , Motasem Alfarra , Ali Thabet , Pablo Arbeláez , Bernard Ghanem

Foundation models (FMs) are driving a prominent shift in biomedical imaging from task-specific models to unified backbone models for diverse tasks. This opens an avenue to integrate imaging, pathology, clinical records, and genomics data…

Quantitative Methods · Quantitative Biology 2026-04-23 Amgad Muneer , Kai Zhang , Ibraheem Hamdi , Rizwan Qureshi , Muhammad Waqas , Shereen Fouad , Hazrat Ali , Syed Muhammad Anwar , Jia Wu

Large Language Models (LLMs) have benefited enormously from scaling, yet these gains are bounded by five fundamental limitations: (1) hallucination, (2) context compression, (3) reasoning degradation, (4) retrieval fragility, and (5)…

The rapid advancement of ML models in critical sectors such as healthcare, finance, and security has intensified the need for robust data security, model integrity, and reliable outputs. Large multimodal foundational models, while crucial…

Cryptography and Security · Computer Science 2024-12-13 Hongyang Zhang , Yue Zhao , Claudio Angione , Harry Yang , James Buban , Ahmad Farhan , Fielding Johnston , Patrick Colangelo

Deep learning models are widely used for various industrial and scientific applications. Even though these models have achieved considerable success in recent years, there exists a lack of understanding of the rationale behind decisions…

Machine Learning · Computer Science 2020-07-08 Swapnil Nitin Shah

Diffusion models have demonstrated impressive capabilities in synthesizing diverse content. However, despite their high-quality outputs, these models often perpetuate social biases, including those related to gender and race. These biases…

Computer Vision and Pattern Recognition · Computer Science 2025-03-27 Yingdong Shi , Changming Li , Yifan Wang , Yongxiang Zhao , Anqi Pang , Sibei Yang , Jingyi Yu , Kan Ren

Although personalized recommendation has been investigated for decades, the wide adoption of Latent Factor Models (LFM) has made the explainability of recommendations a critical issue to both the research community and practical application…

Information Retrieval · Computer Science 2017-08-23 Yongfeng Zhang

Recent advances in large pretrained models have led to their widespread integration as core components in modern software systems. The trend is expected to continue in the foreseeable future. Unlike traditional software systems governed by…

Software Engineering · Computer Science 2025-07-18 Dongming Jin , Zhi Jin , Linyu Li , Xiaohong Chen

Foundation model, which is pre-trained on broad data and is able to adapt to a wide range of tasks, is advancing healthcare. It promotes the development of healthcare artificial intelligence (AI) models, breaking the contradiction between…

Computers and Society · Computer Science 2024-04-05 Yuting He , Fuxiang Huang , Xinrui Jiang , Yuxiang Nie , Minghao Wang , Jiguang Wang , Hao Chen

The growing use of large language models in sensitive domains has exposed a critical weakness: the inability to ensure that private information can be permanently forgotten. Yet these systems still lack reliable mechanisms to guarantee that…

Machine Learning · Computer Science 2025-11-14 James Jin Kang , Dang Bui , Thanh Pham , Huo-Chong Ling

The deep integration of foundation models (FM) with federated learning (FL) enhances personalization and scalability for diverse downstream tasks, making it crucial in sensitive domains like healthcare. Achieving group fairness has become…

Machine Learning · Computer Science 2025-06-24 Yuning Yang , Han Yu , Tianrun Gao , Xiaodong Xu , Guangyu Wang

Formal explainability guarantees the rigor of computed explanations, and so it is paramount in domains where rigor is critical, including those deemed high-risk. Unfortunately, since its inception formal explainability has been hampered by…

Artificial Intelligence · Computer Science 2024-12-04 Xuanxiang Huang , Joao Marques-Silva

Multimodal foundation models (MMFMs) play a crucial role in various applications, including autonomous driving, healthcare, and virtual assistants. However, several studies have revealed vulnerabilities in these models, such as generating…

Large Language Models (LLMs) have recently gained significant attention due to their remarkable capabilities in performing diverse tasks across various domains. However, a thorough evaluation of these models is crucial before deploying them…

The pervasive uncertainty and dynamic nature of real-world environments present significant challenges for the widespread implementation of machine-driven Intelligent Decision-Making (IDM) systems. Consequently, IDM should possess the…

Artificial Intelligence · Computer Science 2023-05-17 Ying Wen , Ziyu Wan , Ming Zhou , Shufang Hou , Zhe Cao , Chenyang Le , Jingxiao Chen , Zheng Tian , Weinan Zhang , Jun Wang

Foundation models pre-trained on massive datasets, including large language models (LLMs), vision-language models (VLMs), and large multimodal models, have demonstrated remarkable success in diverse downstream tasks. However, recent studies…

Machine Learning · Computer Science 2025-07-25 Neil He , Hiren Madhu , Ngoc Bui , Menglin Yang , Rex Ying

Since its foundations, more than one hundred years ago, the field of structural biology has strived to understand and analyze the properties of molecules and their interactions by studying the structure that they take in 3D space. However,…

Biomolecules · Quantitative Biology 2023-02-27 Gabriele Corso
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