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Scientific innovation is pivotal for humanity, and harnessing large language models (LLMs) to generate research ideas could transform discovery. However, existing LLMs often produce simplistic and repetitive suggestions due to their limited…

Artificial Intelligence · Computer Science 2024-10-29 Xiang Hu , Hongyu Fu , Jinge Wang , Yifeng Wang , Zhikun Li , Renjun Xu , Yu Lu , Yaochu Jin , Lili Pan , Zhenzhong Lan

Large Language Models (LLMs) are transforming scientific hypothesis generation and validation by enabling information synthesis, latent relationship discovery, and reasoning augmentation. This survey provides a structured overview of…

Although Large Language Models (LLMs) have demonstrated extraordinary capabilities in many domains, they still have a tendency to hallucinate and generate fictitious responses to user requests. This problem can be alleviated by augmenting…

Information Retrieval · Computer Science 2023-06-09 Jiongnan Liu , Jiajie Jin , Zihan Wang , Jiehan Cheng , Zhicheng Dou , Ji-Rong Wen

Significant scientific discoveries have driven the progress of human civilisation. The explosion of scientific literature and data has created information barriers across disciplines that have slowed the pace of scientific discovery. Large…

Computation and Language · Computer Science 2023-11-13 Biqing Qi , Kaiyan Zhang , Haoxiang Li , Kai Tian , Sihang Zeng , Zhang-Ren Chen , Bowen Zhou

Tree search has become as a representative framework for test-time reasoning with large language models (LLMs), exemplified by methods such as Tree-of-Thought and Monte Carlo Tree Search. However, it remains difficult to provide instant and…

Artificial Intelligence · Computer Science 2026-03-02 Jiaxi Li , Yucheng Shi , Xiao Huang , Jin Lu , Ninghao Liu

The widespread adoption of Large Language Models (LLMs) and publicly available ChatGPT have marked a significant turning point in the integration of Artificial Intelligence (AI) into people's everyday lives. This study examines the ability…

Computation and Language · Computer Science 2025-10-28 Sandeep Kumar , Tirthankar Ghosal , Vinayak Goyal , Asif Ekbal

Autonomous scientific discovery with large language model (LLM)-based agents has recently made substantial progress, demonstrating the ability to automate end-to-end research workflows. However, existing systems largely rely on…

Computational Engineering, Finance, and Science · Computer Science 2026-01-29 Tengyue Xu , Zhuoyang Qian , Gaoge Liu , Li Ling , Zhentao Zhang , Biao Wu , Shuo Zhang , Ke Lu , Wei Shi , Ziqi Wang , Zheng Feng , Yan Luo , Shu Xu , Yongjin Chen , Zhibo Feng , Zhuo Chen , Bruce Yuan , Harry Wang , Kris Chen

Large language models (LLMs) have demonstrated significant potential to accelerate scientific discovery as valuable tools for analyzing data, generating hypotheses, and supporting innovative approaches in various scientific fields. In this…

Computation and Language · Computer Science 2025-10-30 Jin Huang , Silviu Cucerzan , Sujay Kumar Jauhar , Ryen W. White

Scientific idea generation has been extensively studied in creativity theory and computational creativity research, providing valuable frameworks for understanding and implementing creative processes. However, recent work using Large…

Artificial Intelligence · Computer Science 2025-02-18 Tianyang Gu , Jingjin Wang , Zhihao Zhang , HaoHong Li

The exponential growth of academic publications poses challenges for the research process, such as literature review and procedural planning. Large Language Models (LLMs) have emerged as powerful AI tools, especially when combined with…

Applied Physics · Physics 2025-02-13 Joaquin Ramirez-Medina , Mohammadmehdi Ataei , Alidad Amirfazli

Objective: Information retrieval (IR, also known as search) systems are ubiquitous in modern times. How does the emergence of generative artificial intelligence (AI), based on large language models (LLMs), fit into the IR process? Process:…

Information Retrieval · Computer Science 2025-01-20 William R. Hersh

Large language models (LLMs) are increasingly used in scientific research and discovery, supporting tasks ranging from literature retrieval and synthesis to hypothesis generation, autonomous experimentation, and research evaluation.…

Digital Libraries · Computer Science 2026-05-13 Haoxuan Zhang , Ruochi Li , Yang Zhang , Ting Xiao , Jiangping Chen , Junhua Ding , Haihua Chen

Despite interdisciplinary research leading to larger and longer-term impact, most work remains confined to single-domain academic silos. Recent AI-based approaches to scientific discovery show promise for interdisciplinary research, but…

Computation and Language · Computer Science 2026-03-13 Priyanka Kargupta , Shuhaib Mehri , Dilek Hakkani-Tur , Jiawei Han

The rapid growth of scientific literature imposes significant challenges for researchers endeavoring to stay updated with the latest advancements in their fields and delve into new areas. We introduce OpenResearcher, an innovative platform…

The rapid acceleration of scientific publishing has created substantial challenges for researchers attempting to discover, contextualize, and interpret relevant literature. Traditional keyword-based search systems provide limited semantic…

Information Retrieval · Computer Science 2025-12-16 Sina Jani , Arman Heidari , Amirmohammad Anvari , Zahra Rahimi

While search is the predominant method of accessing information, formulating effective queries remains a challenging task, especially for situations where the users are not familiar with a domain, or searching for documents in other…

Artificial Intelligence · Computer Science 2023-11-21 Kaustubh D. Dhole , Ramraj Chandradevan , Eugene Agichtein

Many promising-looking ideas in AI research fail to deliver, but their validation takes substantial human labor and compute. Predicting an idea's chance of success is thus crucial for accelerating empirical AI research, a skill that even…

Artificial Intelligence · Computer Science 2025-06-03 Jiaxin Wen , Chenglei Si , Yueh-han Chen , He He , Shi Feng

The application of Large Language Models (LLMs) in accelerating scientific discovery has garnered increasing attention, with a key focus on constructing research agents endowed with innovative capability, i.e., the ability to autonomously…

Computation and Language · Computer Science 2026-02-24 Tianyu Fan , Fengji Zhang , Yuxiang Zheng , Bei Chen , Xinyao Niu , Chengen Huang , Junyang Lin , Chao Huang

There has been a surge of interest in harnessing the reasoning capabilities of Large Language Models (LLMs) to accelerate scientific discovery. While existing approaches rely on grounding the discovery process within the relevant…

Artificial Intelligence · Computer Science 2025-06-03 Aniketh Garikaparthi , Manasi Patwardhan , Aditya Sanjiv Kanade , Aman Hassan , Lovekesh Vig , Arman Cohan

Given the remarkable performance of Large Language Models (LLMs), an important question arises: Can LLMs conduct human-like scientific research and discover new knowledge, and act as an AI scientist? Scientific discovery is an iterative…

Machine Learning · Computer Science 2025-02-24 Tingting Chen , Srinivas Anumasa , Beibei Lin , Vedant Shah , Anirudh Goyal , Dianbo Liu