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This paper presents a hypothesis-driven approach to improve AI-supported decision-making that is based on the Evaluative AI paradigm - a conceptual framework that proposes providing users with evidence for or against a given hypothesis. We…

Artificial Intelligence · Computer Science 2025-08-28 Thao Le , Tim Miller , Liz Sonenberg , Ronal Singh , H. Peter Soyer

The rapid proliferation of artificial intelligence (AI) models and methods presents growing challenges for research software engineers and researchers who must select, integrate, and maintain appropriate models within complex research…

Across a growing number of fields, human decision making is supported by predictions from AI models. However, we still lack a deep understanding of the effects of adoption of these technologies. In this paper, we introduce a general…

Artificial Intelligence · Computer Science 2026-02-26 Otto Nyberg , Fausto Carcassi , Giovanni Cinà

Conventional automated decision-support systems often prioritize predictive accuracy, overlooking the complexities of real-world settings where stakeholders' preferences may diverge or conflict. This can lead to outcomes that disadvantage…

Machine Learning · Computer Science 2025-11-25 Vittoria Vineis , Giuseppe Perelli , Gabriele Tolomei

Regulatory frameworks for the use of AI are emerging. However, they trail behind the fast-evolving malicious AI technologies that can quickly cause lasting societal damage. In response, we introduce a pioneering Assistive AI framework…

Dermatological conditions affect 1.9 billion people globally, yet accurate diagnosis remains challenging due to limited specialist availability and complex clinical presentations. Family history significantly influences skin disease…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Satya Narayana Panda , Vaishnavi Kukkala , Spandana Iyer

This research focuses on evaluating and enhancing data readiness for the development of an Artificial Intelligence (AI)-based Clinical Decision Support System (CDSS) in the context of skin cancer treatment. The study, conducted at the Skin…

Artificial Intelligence · Computer Science 2025-03-13 Joscha Grüger , Tobias Geyer , Tobias Brix , Michael Storck , Sonja Leson , Laura Bley , Carsten Weishaupt , Ralph Bergmann , Stephan A. Braun

AI systems increasingly support human decision-making. In many cases, despite the algorithm's superior performance, the final decision remains in human hands. For example, an AI may assist doctors in determining which diagnostic tests to…

Artificial Intelligence · Computer Science 2026-02-20 Gali Noti , Kate Donahue , Jon Kleinberg , Sigal Oren

From school admissions to hiring and investment decisions, the first step behind many high-stakes decision-making processes is "deciding how to decide." Formulating effective criteria to guide decision-making requires an iterative process…

Human-Computer Interaction · Computer Science 2025-04-18 Chance Castañeda , Jessica Mindel , Will Page , Hayden Stec , Manqing Yu , Kenneth Holstein

Artificial intelligence (AI) holds great promise for supporting clinical trials, from patient recruitment and endpoint assessment to treatment response prediction. However, deploying AI without safeguards poses significant risks,…

Machine Learning · Computer Science 2025-10-09 Yao Chen , David Ohlssen , Aimee Readie , Gregory Ligozio , Ruvie Martin , Thibaud Coroller

Early detection of skin cancers like melanoma is crucial to ensure high chances of survival for patients. Clinical application of Deep Learning (DL)-based Decision Support Systems (DSS) for skin cancer screening has the potential to improve…

Computer Vision and Pattern Recognition · Computer Science 2021-03-10 Adriano Lucieri , Andreas Dengel , Sheraz Ahmed

Cutaneous malignancies demand early detection for favorable outcomes, yet current diagnostics suffer from inter-observer variability and access disparities. While AI shows promise, existing dermatological systems are limited by homogeneous…

Computer Vision and Pattern Recognition · Computer Science 2025-10-09 Sher Khan , Raz Muhammad , Adil Hussain , Muhammad Sajjad , Muhammad Rashid

AI-driven precision oncology has the transformative potential to reshape cancer treatment by leveraging the power of AI models to analyze the interaction between complex patient characteristics and their corresponding treatment outcomes.…

With the rapid development of AI-based decision aids, different forms of AI assistance have been increasingly integrated into the human decision making processes. To best support humans in decision making, it is essential to quantitatively…

Human-Computer Interaction · Computer Science 2024-01-12 Zhuoyan Li , Zhuoran Lu , Ming Yin

This study empirically examines the "Evaluative AI" framework, which aims to enhance the decision-making process for AI users by transitioning from a recommendation-based approach to a hypothesis-driven one. Rather than offering direct…

Human-Computer Interaction · Computer Science 2024-11-14 Jaroslaw Kornowicz

In the modern healthcare system, rapidly expanding costs/complexity, the growing myriad of treatment options, and exploding information streams that often do not effectively reach the front lines hinder the ability to choose optimal…

Artificial Intelligence · Computer Science 2018-10-09 Casey C. Bennett , Kris Hauser

Over the past decades, cognitive neuroscientists and behavioral economists have recognized the value of describing the process of decision making in detail and modeling the emergence of decisions over time. For example, the time it takes to…

Neurons and Cognition · Quantitative Biology 2025-07-24 Mrugsen Nagsen Gopnarayan , Jaan Aru , Sebastian Gluth

AI-enabled decision-support systems aim to help medical providers rapidly make decisions with limited information during medical emergencies. A critical challenge in developing these systems is supporting providers in interpreting the…

Ensuring trustworthiness is fundamental to the development of artificial intelligence (AI) that is considered societally responsible, particularly in cancer diagnostics, where a misdiagnosis can have dire consequences. Current digital…

Image and Video Processing · Electrical Eng. & Systems 2025-01-03 Xiaoge Zhang , Tao Wang , Chao Yan , Fedaa Najdawi , Kai Zhou , Yuan Ma , Yiu-ming Cheung , Bradley A. Malin

In AI-assisted decision-making, humans often passively review AI's suggestion and decide whether to accept or reject it as a whole. In such a paradigm, humans are found to rarely trigger analytical thinking and face difficulties in…

Human-Computer Interaction · Computer Science 2025-03-13 Shuai Ma , Qiaoyi Chen , Xinru Wang , Chengbo Zheng , Zhenhui Peng , Ming Yin , Xiaojuan Ma
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