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The study of associations between an individual's age and imaging and non-imaging data is an active research area that attempts to aid understanding of the effects and patterns of aging. In this work we have conducted a supervoxel-wise…

Image and Video Processing · Electrical Eng. & Systems 2026-04-20 Johan Öfverstedt , Elin Lundström , Göran Bergström , Joel Kullberg , Håkan Ahlström

Cardiovascular disease, the leading cause of death globally, is an age-related disease. Understanding the morphological and functional changes of the heart during ageing is a key scientific question, the answer to which will help us define…

Image and Video Processing · Electrical Eng. & Systems 2022-10-11 Mengyun Qiao , Berke Doga Basaran , Huaqi Qiu , Shuo Wang , Yi Guo , Yuanyuan Wang , Paul M. Matthews , Daniel Rueckert , Wenjia Bai

Age prediction is an important part of medical assessments and research. It can aid in detecting diseases as well as abnormal ageing by highlighting potential discrepancies between chronological and biological age. To improve understanding…

Image and Video Processing · Electrical Eng. & Systems 2024-11-28 Sophie Starck , Yadunandan Vivekanand Kini , Jessica Johanna Maria Ritter , Rickmer Braren , Daniel Rueckert , Tamara Mueller

The traditional manual age estimation method is crucial labor based on many kinds of the X-Ray image. Some current studies have shown that lateral cephalometric(LC) images can be used to estimate age. However, these methods are based on…

Image and Video Processing · Electrical Eng. & Systems 2021-12-08 Ningtao Liu

Coronary computed tomography angiography (CCTA) provides 3D information on obstructive coronary artery disease, but cannot fully visualize high-resolution features within the vessel wall. Intravascular imaging, in contrast, can spatially…

Image and Video Processing · Electrical Eng. & Systems 2025-09-10 Karim Kadry , Abhishek Karmakar , Andreas Schuh , Kersten Peterson , Michiel Schaap , David Marlevi , Charles Taylor , Elazer Edelman , Farhad Nezami

Aging is a highly complex and heterogeneous process that progresses at different rates across individuals, making biological age (BA) a more accurate indicator of physiological decline than chronological age. While previous studies have…

Genomics · Quantitative Biology 2025-10-24 Huifa Li , Feilong Tang , Haochen Xue , Yulong Li , Xinlin Zhuang , Bin Zhang , Eran Segal , Imran Razzak

We propose new methods for the prediction of 5-year mortality in elderly individuals using chest computed tomography (CT). The methods consist of a classifier that performs this prediction using a set of features extracted from the CT image…

Computer Vision and Pattern Recognition · Computer Science 2016-10-04 Gustavo Carneiro , Luke Oakden-Rayner , Andrew P. Bradley , Jacinto Nascimento , Lyle Palmer

The concept of biological age (BA), although important in clinical practice, is hard to grasp mainly due to the lack of a clearly defined reference standard. For specific applications, especially in pediatrics, medical image data are used…

Image and Video Processing · Electrical Eng. & Systems 2021-03-22 Karim Armanious , Sherif Abdulatif , Wenbin Shi , Shashank Salian , Thomas Küstner , Daniel Weiskopf , Tobias Hepp , Sergios Gatidis , Bin Yang

Bone age assessment gives us evidence to analyze the children growth status and the rejuvenation involved chronological and biological ages. All the previous works consider left-hand X-ray image of a child in their works. In this paper, we…

Computer Vision and Pattern Recognition · Computer Science 2019-01-30 Hai-Duong Nguyen , Soo-Hyung Kim

Background: Photoplethysmography (PPG), increasingly available through wearable devices, provides a non-invasive means of monitoring human hemodynamics. In this study, we introduce artificial intelligence-derived photoplethysmography…

Signal Processing · Electrical Eng. & Systems 2025-09-26 Guangkun Nie , Qinghao Zhao , Gongzheng Tang , Yaxin Li , Shenda Hong

Age estimation has attracted attention for its various medical applications. There are many studies on human age estimation from biomedical images. However, there is no research done on mammograms for age estimation, as far as we know. The…

Computer Vision and Pattern Recognition · Computer Science 2022-07-14 Charitha Dissanayake Lekamlage , Fabia Afzal , Erik Westerberg , Abbas Cheddad

Alzheimer's Disease and normal aging are both characterized by brain atrophy. The question of whether AD-related brain atrophy represents accelerated aging or a neurodegeneration process distinct from that in normal aging remains…

Computer Vision and Pattern Recognition · Computer Science 2025-04-08 Jingru Fu , Daniel Ferreira , Örjan Smedby , Rodrigo Moreno

An accurate assessment of the cardiovascular system and prediction of cardiovascular diseases (CVDs) are crucial. Measured cardiac blood flow data provide insights about patient-specific hemodynamics, where many specialized techniques have…

In recent years, there are various methods of estimating Biological Age (BA) have been developed. Especially with the development of machine learning (ML), there are more and more types of BA predictions, and the accuracy has been greatly…

Computer Vision and Pattern Recognition · Computer Science 2022-06-28 Zhaonian Zhang , Richard Jiang , Danny Crookes , Paul Chazot

Normative aging trends of the brain can serve as an important reference in the assessment of neurological structural disorders. Such models are typically developed from longitudinal brain image data -- follow-up data of the same subject…

Computer Vision and Pattern Recognition · Computer Science 2021-06-29 Alphin J Thottupattu , Jayanthi Sivaswamy , Venkateswaran P. Krishnan

We present the findings of an experimental study whereby we correlate the changes in the morphology of the photoplethysmography (PPG) signal to healthy aging. Under this pretext, we estimate the biological age of a person as well as the age…

In this study, we propose the use of persistent homology -- specifically Betti curves for brain age prediction and for distinguishing between healthy and pathological aging. The proposed framework is applied to 100 structural MRI scans from…

Neurons and Cognition · Quantitative Biology 2025-11-11 Debanjali Bhattacharya , Neelam Sinha

Accurate bone strength prediction is essential for assessing fracture risk, particularly in aging populations and individuals with osteoporosis. Bone imaging has evolved from X-rays and DXA to clinical computed tomography (CT), and now to…

Quantitative Methods · Quantitative Biology 2025-12-04 John Rick Manzanares , Richard Leslie Abel , Paweł Dłotko

Computed Tomography Coronary Angiography (CTCA) is a non-invasive method to evaluate coronary artery anatomy and disease. CTCA is ideal for geometry reconstruction to create virtual models of coronary arteries. To our knowledge there is no…

Computer Vision and Pattern Recognition · Computer Science 2022-11-04 Ramtin Gharleghi , Dona Adikari , Katy Ellenberger , Mark Webster , Chris Ellis , Arcot Sowmya , Sze-Yuan Ooi , Susann Beier

Sex-based differences in cardiovascular disease are well documented, yet the precise nature and extent of these discrepancies in cardiac anatomy remain incompletely understood. Traditional scaling models often fail to capture the interplay…

Tissues and Organs · Quantitative Biology 2025-03-04 Beatrice Moscoloni , Cameron Beeche , Julio A. Chirinos , Patrick Segers , Mathias Peirlinck
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