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We study elasticity-driven morphological transitions of soft spherical core shell structures in which the core can be treated as an isotropic elastic continuum and the surface or shell as a tensionless liquid layer, whose elastic response…

Soft Condensed Matter · Physics 2013-11-13 Craig Fogle , Amy C. Rowat , Alex J. Levine , Joseph Rudnick

Organogenesis involves large deformations and complex shape changes that require elaborate mechanical regulation. Models of tissue biomechanics have been introduced to account for the coupling between mechanical response and biochemical…

Soft Condensed Matter · Physics 2025-04-16 Patrick W. Alford , Luiza Angheluta , Jorge Vinals

The wrinkling of thin elastic objects provides a means of generating regular patterning at small scales in applications ranging from photovoltaics to microfluidic devices. Static wrinkle patterns are known to be governed by an energetic…

Soft Condensed Matter · Physics 2020-01-28 Finn Box , Doireann O'Kiely , Ousmane Kodio , Maxime Inizan , Alfonso A. Castrejon-Pita , Dominic Vella

Epithelial tissues act as barriers and, therefore, must repair themselves, respond to environmental changes and grow without compromising their integrity. Consequently, they exhibit complex viscoelastic rheological behavior where…

Soft Condensed Matter · Physics 2022-10-04 Sijie Tong , Navreeta K. Singh , Rastko Sknepnek , Andrej Kosmrlj

Several experiments have demonstrated the existence of an electro-mechanical effect in many biological tissues and hydrogels, and its actual influence on growth, migration, and pattern formation. Here, to model these interactions and…

Soft Condensed Matter · Physics 2020-07-07 Yangkun Du , Yipin Su , Chaofeng Lu , Weiqiu Chen , Michel Destrade

We study the self-assembly of colloidal microgel particles at a quasi-two-dimensional air-water interface of a drying droplet. Using bright-field microscopy, we demonstrate that increasing particle elasticity drives interfacial organization…

Soft Condensed Matter · Physics 2026-03-10 Vaibhav Raj Singh Parmar , Sayantan Chanda , Rituparno Mandal , Ranjini Bandyopadhyay

Epithelial monolayers are a central building block of complex organisms. Topological defects have emerged as important elements for single cell behavior in flat epithelia. Here we theoretically study such defects in a three-dimensional…

Biological Physics · Physics 2025-02-19 Oliver M. Drozdowski , Ulrich S. Schwarz

A rectangular plate of dielectric elastomer exhibiting gradients of material properties through its thickness will deform inhomogeneously when a potential difference is applied to compliant electrodes on its major surfaces, because each…

Soft Condensed Matter · Physics 2020-12-08 Yipin Su , Ray W. Ogden , Michel Destrade

Experimentally measuring the elastic properties of thin biological surfaces is non-trivial, particularly when they are curved. One technique that may be used is the indentation of a thin sheet of material by a rigid indenter, whilst…

During development, epithelial tissues undergo extensive morphogenesis based on coordinated changes of cell shape and position over time. Continuum mechanics describes tissue mechanical state and shape changes in terms of strain and stress.…

Cell Behavior · Quantitative Biology 2012-05-14 Isabelle Bonnet , Philippe Marcq , Floris Bosveld , Luc Fetler , Yohanns Bellaiche , Francois Graner

Nanoscale molecular transport plays a crucial role in regulating mass diffusion and responsiveness in condensed matter systems. In soft porous crystals, in particular, adsorption of guest molecules induces host framework deformation and…

Soft Condensed Matter · Physics 2026-01-28 Kota Mitsumoto , Kyohei Takae

The mechanical response of naturally abundant amorphous solids such as gels, jammed grains, and biological tissues are not described by the conventional paradigm of broken symmetry that defines crystalline elasticity. In contrast, the…

Disordered Systems and Neural Networks · Physics 2020-09-29 Jishnu N. Nampoothiri , Yinqiao Wang , Kabir Ramola , Jie Zhang , Subhro Bhattacharjee , Bulbul Chakraborty

A key process in the life of any multicellular organism is its development from a single egg into a full grown adult. The first step in this process often consists of forming a tissue layer out of randomly placed cells on the surface of the…

A notable feature of the elephant trunk is the pronounced wrinkling that enables its great flexibility. Here, we devise a general mathematical model that accounts for the characteristic skin wrinkles formed during morphogenesis in the…

Biological Physics · Physics 2025-02-07 Yang Liu , Alain Goriely , L. Angela Mihai

Living tissues experience various external forces on cells, influencing their behaviour, physiology, shape, gene expression, and destiny through interactions with their environment. Despite much research done in this area, challenges remain…

Quantitative Methods · Quantitative Biology 2024-03-05 Akepogu Venkateshwarlu , Akshayveer , Sundeep Singh , Roderick Melnik

As we enter the age of designer matter - where objects can morph and change shape on command - what tools do we need to create shape-shifting structures? At the heart of an elastic deformation is the combination of dilation and distortion,…

Soft Condensed Matter · Physics 2018-09-14 Douglas P. Holmes

We study the lubrication of fluid-immersed soft interfaces and show that elastic deformation couples tangential and normal forces and thus generates lift. We consider materials that deform easily, due to either geometry (e.g. a shell) or…

Soft Condensed Matter · Physics 2009-11-10 J. M. Skotheim , L. Mahadevan

A detailed understanding of the interface between living cells and substrate materials is of rising importance in many fields of medicine, biology and biotechnology. Cells at interfaces often form epithelia. The physical barrier that they…

The formation of periodic wrinkles in soft layered materials due to mechanical instabilities is prevalent in nature and has been proposed for use in multiple applications. However, such phenomena have been explored predominantly in…

We address the folding induced by differential growth in soft layered solids via an elementary model that consists of a soft growing neo-Hookean elastic layer adhered to a deep elastic substrate. As the layer/substrate modulus ratio is…

Soft Condensed Matter · Physics 2015-09-30 Tuomas Tallinen , John S. Biggins
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